{"id":"pecilocin","rwe":[{"pmid":"138665","year":"1977","title":"[Pecilocin allergy].","finding":"","journal":"Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete","studyType":"Clinical Study"},{"pmid":"1085044","year":"1976","title":"[Antimycotic antibiotics (author's transl)].","finding":"","journal":"Tijdschrift voor diergeneeskunde","studyType":"Clinical Study"},{"pmid":"1149649","year":"1975","title":"Miconazole: a review of its antifungal activity and therapeutic efficacy.","finding":"","journal":"Drugs","studyType":"Clinical Study"},{"pmid":"4900295","year":"1969","title":"A comparative trial of chlorphenesin and pecilocin in a prison community.","finding":"","journal":"The British journal of clinical practice","studyType":"Clinical Study"}],"tags":[{"label":"pecilocin","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"D01AA04","category":"atc"},{"label":"Active","category":"status"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"leofungine","offLabel":[],"synonyms":["pecilocin","leofungine"],"timeline":[],"approvals":[],"brandName":"Leofungine","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"pecilocin","explanation":"Think of it like a key that fits into a lock, but instead of unlocking a door, it blocks a specific pathway in the cell. This can help slow down or stop the growth of certain cells, which can be beneficial in treating diseases. However, the exact details of how it works are still a mystery.","oneSentence":"Leofungine works by inhibiting certain cellular processes, but the exact mechanism is unknown.","technicalDetail":"Leofungine is a small molecule that interacts with cellular targets, potentially inhibiting protein-protein interactions or modulating signaling pathways, although the precise molecular mechanisms remain unclear."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/3419","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=PECILOCIN","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T15:15:57.599958","biosimilars":[],"competitors":[{"drugName":"nystatin","drugSlug":"nystatin","fdaApproval":"1964-07-08","genericCount":48,"patentStatus":"Off-patent — generic available","relationship":"same-class"},{"drugName":"natamycin","drugSlug":"natamycin","fdaApproval":"1978-10-30","patentStatus":"Unknown","relationship":"same-class"},{"drugName":"griseofulvin","drugSlug":"griseofulvin","fdaApproval":"1962-08-22","genericCount":3,"patentStatus":"Off-patent — generic available","relationship":"same-class"}],"genericName":"pecilocin","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[{"drugId":"nystatin","brandName":"nystatin","genericName":"nystatin","approvalYear":"1964","relationship":"same-class"},{"drugId":"natamycin","brandName":"natamycin","genericName":"natamycin","approvalYear":"1978","relationship":"same-class"},{"drugId":"griseofulvin","brandName":"griseofulvin","genericName":"griseofulvin","approvalYear":"1962","relationship":"same-class"}],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"UNII":"TSA7W27MF8","CHEBI":"CHEBI:32289","INN_ID":"2145","UMLSCUI":"C0070200","ChEMBL_ID":"CHEMBL486174","DRUGBANK_ID":"DB13459","PUBCHEM_CID":"5282176","MESH_SUPPLEMENTAL_RECORD_UI":"C001405"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":0,"therapeuticAreas":["Other"],"atcClassification":{"source":"DrugCentral","atcCode":"D01AA04","allCodes":["D01AA04"]},"biosimilarFilings":[],"recentPublications":[{"date":"1977 Jan","pmid":"138665","title":"[Pecilocin allergy].","journal":"Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete"},{"date":"1976 Aug 15","pmid":"1085044","title":"[Antimycotic antibiotics (author's transl)].","journal":"Tijdschrift voor diergeneeskunde"},{"date":"1975","pmid":"1149649","title":"Miconazole: a review of its antifungal activity and therapeutic efficacy.","journal":"Drugs"},{"date":"1969 Nov","pmid":"4900295","title":"A comparative trial of chlorphenesin and pecilocin in a prison community.","journal":"The British journal of clinical practice"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Leofungine is a small molecule with the synonyms NSC-291839, PECILOCIN, and others. Its exact mechanism and indications are not specified in the provided information, but it is listed as a small molecule in ChEMBL.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}