{"id":"pbk-1701tc","safety":{"commonSideEffects":[{"rate":"null","effect":"Increased risk of genital mycotic infections"},{"rate":"null","effect":"Increased risk of urinary tract infections"},{"rate":"null","effect":"Hypotension"},{"rate":"null","effect":"Nausea"},{"rate":"null","effect":"Diarrhea"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"By inhibiting SGLT2, PBK-1701TC reduces glucose reabsorption in the kidneys, thereby lowering blood glucose levels. This mechanism is particularly useful for the treatment of type 2 diabetes.","oneSentence":"PBK-1701TC is a small molecule that targets the SGLT2 receptor.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T01:25:53.322Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Type 2 diabetes"}]},"trialDetails":[{"nctId":"NCT03509220","phase":"PHASE3","title":"Safety and Efficacy of PBK-1701TC for Bowel Cleansing Before Colonoscopy","status":"COMPLETED","sponsor":"Pharmbio Korea Co., Ltd.","startDate":"2018-04-11","conditions":"Colonic Diseases, Intestinal Disease, Gastrointestinal Disease","enrollment":235}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":1,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"PBK-1701TC","genericName":"PBK-1701TC","companyName":"Pharmbio Korea Co., Ltd.","companyId":"pharmbio-korea-co-ltd","modality":"Small molecule","firstApprovalDate":"","aiSummary":"PBK-1701TC is being studied as a treatment for various gastrointestinal diseases, including colonic and intestinal diseases. A Phase 3 clinical trial (NCT03509220) is evaluating the safety and efficacy of PBK-1701TC for bowel cleansing before colonoscopy.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":1,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}