{"id":"patients-receive-microporous-polysaccharide-hemospheres","safety":{"commonSideEffects":[{"rate":null,"effect":"Minimal systemic absorption"},{"rate":null,"effect":"Local tissue reaction"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"These hemospheres are composed of plant-derived polysaccharides with a microporous structure that absorbs blood and concentrates clotting factors and platelets at the wound site, accelerating the natural coagulation cascade. The particles are bioabsorbable and gradually break down as hemostasis is achieved, making them suitable for topical hemostatic applications in surgical settings.","oneSentence":"Microporous polysaccharide hemospheres are biocompatible particles that promote hemostasis by providing a physical scaffold for blood clotting and platelet aggregation.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-27T23:59:55.814Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Surgical hemostasis and bleeding control"}]},"trialDetails":[{"nctId":"NCT06824831","phase":"PHASE4","title":"Use of Microporous Polysaccharide Hemispheres in Breast Cancer Patients Undergoing Mastectomy","status":"COMPLETED","sponsor":"Fundación para la Investigación del Hospital Clínico de Valencia","startDate":"2020-06-01","conditions":"Mastectomy, Lymphadenectomy, Breast Neoplasm Malignant Female","enrollment":120}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":10,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"Patients receive microporous polysaccharide hemospheres.","genericName":"Patients receive microporous polysaccharide hemospheres.","companyName":"Fundación para la Investigación del Hospital Clínico de Valencia","companyId":"fundaci-n-para-la-investigaci-n-del-hospital-cl-nico-de-valencia","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Microporous polysaccharide hemospheres are biocompatible particles that promote hemostasis by providing a physical scaffold for platelet aggregation and blood clotting. Used for Intraoperative hemostasis and control of bleeding during surgical procedures.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":1,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}