{"id":"parafon-forte","safety":{"commonSideEffects":[{"rate":null,"effect":"Dizziness"},{"rate":null,"effect":"Drowsiness"},{"rate":null,"effect":"Headache"},{"rate":null,"effect":"Gastrointestinal upset"},{"rate":null,"effect":"Hepatotoxicity (rare)"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"The active ingredient is chlorzoxazone, which acts as a centrally-acting skeletal muscle relaxant. It reduces muscle spasms and associated pain by depressing polysynaptic reflexes in the spinal cord and brainstem, rather than by direct action on skeletal muscle. It is typically used as an adjunct to rest and physical therapy for acute musculoskeletal conditions.","oneSentence":"Parafon Forte is a muscle relaxant that works by depressing activity in the central nervous system to reduce muscle tension and pain.","_ai_confidence":"high"},"_scrapedAt":"2026-03-27T23:59:44.871Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Acute musculoskeletal pain and muscle spasms"}]},"trialDetails":[{"nctId":"NCT01342341","phase":"PHASE4","title":"Placebo-Controlled Cross Over Trial of Chlorzoxazone Intake","status":"COMPLETED","sponsor":"University of California, San Francisco","startDate":"2011-04","conditions":"Alcohol Abuse","enrollment":48}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":7,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["Chlorzoxazone"],"phase":"marketed","status":"active","brandName":"Parafon Forte","genericName":"Parafon Forte","companyName":"University of California, San Francisco","companyId":"university-of-california-san-francisco","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Parafon Forte is a muscle relaxant that works by depressing activity in the central nervous system to reduce muscle tension and pain. Used for Acute musculoskeletal pain and muscle spasms, Adjunctive therapy for acute, painful musculoskeletal conditions.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}