{"id":"paracetamol","rwe":[{"pmid":"41901258","year":"2026","title":"Comparative Evaluation of Electronic Syringe and Pan Coating Techniques for Loading of FDM 3D Printed Tablets.","finding":"","journal":"Pharmaceuticals (Basel, Switzerland)","studyType":"Clinical Study"},{"pmid":"41899312","year":"2026","title":"Clinical Characteristics and Outcomes of Hospitalized Malaria Patients in Rural Madagascar.","finding":"","journal":"Journal of clinical medicine","studyType":"Clinical Study"},{"pmid":"41898408","year":"2026","title":"Potential Therapeutic Strategies for Steatosis, Oxidative Stress, Inflammation, and Fibrosis in Liver Disease.","finding":"","journal":"International journal of molecular sciences","studyType":"Clinical Study"},{"pmid":"41896927","year":"2026","title":"Toxicological evaluation of paracetamol and ibuprofen: genetic and hematological alterations in male albino mice.","finding":"","journal":"BMC pharmacology & toxicology","studyType":"Clinical Study"},{"pmid":"41895309","year":"2026","title":"Familial confounding and causal inference in child and adolescent neurodevelopment and mental health.","finding":"","journal":"The Lancet. Child & adolescent health","studyType":"Clinical Study"}],"_fda":{"id":"9bd24daa-3c59-4608-b967-d4fe2640358b","set_id":"00146b91-008d-4b16-95b0-6077f98821be","openfda":{"unii":["362O9ITL9D"],"route":["ORAL"],"rxcui":["198440"],"spl_id":["9bd24daa-3c59-4608-b967-d4fe2640358b"],"brand_name":["basic care acetaminophen"],"spl_set_id":["00146b91-008d-4b16-95b0-6077f98821be"],"package_ndc":["72288-300-78","72288-300-79"],"product_ndc":["72288-300"],"generic_name":["ACETAMINOPHEN"],"product_type":["HUMAN OTC DRUG"],"substance_name":["ACETAMINOPHEN"],"manufacturer_name":["Amazon.com Services LLC"],"application_number":["M013"],"is_original_packager":[true]},"purpose":["Purpose Pain reliever/fever reducer"],"version":"3","stop_use":["Stop use and ask a doctor if • pain gets worse or lasts more than 10 days • fever gets worse or lasts more than 3 days • new symptoms occur • redness or swelling is present These could be signs of a serious condition."],"warnings":["Warnings Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take • more than 4,000 mg of acetaminophen in 24 hours • with other drugs containing acetaminophen • 3 or more alcoholic drinks every day while using this product Allergy alert: Acetaminophen may cause severe skin reactions. Symptoms may include: • skin reddening • blisters • rash If a skin reaction occurs, stop use and seek medical help right away. Do not use • with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist. • if you have ever had an allergic reaction to this product or any of its ingredients Ask a doctor before use if you have liver disease Ask a doctor or pharmacist before use if you are taking the blood thinning drug warfarin Stop use and ask a doctor if • pain gets worse or lasts more than 10 days • fever gets worse or lasts more than 3 days • new symptoms occur • redness or swelling is present These could be signs of a serious condition. If pregnant or breast-feeding, ask a health professional before use. Keep out of reach of children. Overdose warning: In case of overdose, get medical help or contact a Poison Control Center right away (1-800-222-1222). Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms."],"questions":["Questions or comments? 1-800-719-9260"],"ask_doctor":["Ask a doctor before use if you have liver disease"],"do_not_use":["Do not use • with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist. • if you have ever had an allergic reaction to this product or any of its ingredients"],"effective_time":"20241024","active_ingredient":["Active ingredient (in each caplet) Acetaminophen 500 mg"],"inactive_ingredient":["Inactive ingredients croscarmellose sodium, crospovidone, FD&C red #40 aluminum lake, FD&C yellow #6 aluminum lake, hypromellose, mica-based pearlescent pigment, polyethylene glycol, polysorbate 80, povidone, pregelatinized starch, stearic acid"],"storage_and_handling":["Other information • store at 20-25 ° C (68-77 ° F)"],"indications_and_usage":["Uses • temporarily relieves minor aches and pains due to: • headache • muscular aches • backache • minor pain of arthritis • the common cold • toothache • premenstrual and menstrual cramps • temporarily reduces fever"],"ask_doctor_or_pharmacist":["Ask a doctor or pharmacist before use if you are taking the blood thinning drug warfarin"],"dosage_and_administration":["Directions • do not take more than directed (see overdose warning) adults and children 12 years and over • take 2 caplets every 6 hours while symptoms last • do not take more than 6 caplets in 24 hours, unless directed by a doctor • do not use for more than 10 days unless directed by a doctor children under 12 years ask a doctor"],"spl_product_data_elements":["basic care acetaminophen Acetaminophen ACETAMINOPHEN ACETAMINOPHEN CROSCARMELLOSE SODIUM CROSPOVIDONE (120 .MU.M) HYPROMELLOSE, UNSPECIFIED POLYETHYLENE GLYCOL, UNSPECIFIED POLYSORBATE 80 POVIDONE, UNSPECIFIED STEARIC ACID FD&C RED NO. 40 FD&C YELLOW NO. 6 3S0"],"pregnancy_or_breast_feeding":["If pregnant or breast-feeding, ask a health professional before use."],"keep_out_of_reach_of_children":["Keep out of reach of children. Overdose warning: In case of overdose, get medical help or contact a Poison Control Center right away (1-800-222-1222). Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms."],"dosage_and_administration_table":["
adults and children 12 years and over
•
take 2 caplets every 6 hours while symptoms last
•
do not take more than 6 caplets in 24 hours, unless directed by a doctor
•
do not use for more than 10 days unless directed by a doctor