{"id":"pain-relief-ointment","safety":{"commonSideEffects":[{"rate":null,"effect":"Skin irritation or rash"},{"rate":null,"effect":"Burning or stinging sensation at application site"},{"rate":null,"effect":"Allergic contact dermatitis"}]},"_chembl":null,"_dailymed":{"setId":"374d89b6-9305-9adf-e063-6394a90adb32","title":"HEMORRHOIDAL PAIN RELIEF (HEMORRHOIDAL PAIN RELIEF OINTMENT) OINTMENT [NEILMED PHARMACEUTICALS INC.]"},"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Topical pain relief ointments typically contain analgesic and/or anti-inflammatory agents (such as menthol, camphor, salicylates, or NSAIDs) that penetrate the skin to desensitize nerve endings and reduce inflammatory mediators in the affected tissue. The exact active ingredients and their concentrations determine the specific mechanism, but the general approach is local delivery to avoid systemic exposure while providing targeted pain relief.","oneSentence":"Pain Relief Ointment provides topical analgesia by delivering active ingredients through the skin to reduce localized pain and inflammation.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T04:20:37.603Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Localized musculoskeletal pain and minor aches"},{"name":"Arthritis pain relief"}]},"trialDetails":[{"nctId":"NCT07391501","phase":"PHASE4","title":"Nitroglycerin Ointment for Pain Relief After Endoscopic Hemorrhoid Band Ligation","status":"NOT_YET_RECRUITING","sponsor":"Ying Zhu","startDate":"2026-02-01","conditions":"Internal Hemorrhoids, Postoperative Pain After Endoscopic Rubber Band Ligation","enrollment":68},{"nctId":"NCT03859011","phase":"NA","title":"Acupuncture Relief for Chronic Neck Pain","status":"COMPLETED","sponsor":"5 Element Institute","startDate":"2022-08-30","conditions":"Neck Pain, Posterior","enrollment":75},{"nctId":"NCT07200362","phase":"","title":"Study of Compound Nanxing Zhitong Ointment in the Treatment of Chronic Pain in Musculoskeletal System","status":"COMPLETED","sponsor":"Jiangsu Kanion Pharmaceutical Co., Ltd","startDate":"2021-10-30","conditions":"Chronic Primary Musculoskeletal Pain","enrollment":3029},{"nctId":"NCT06102291","phase":"NA","title":"Acupoint Application With Yanqing Zhitong Ointment for Chronic Non-specific Low Back Pain","status":"ACTIVE_NOT_RECRUITING","sponsor":"ZhanYJ","startDate":"2022-07-01","conditions":"Non-specific Low Back Pain","enrollment":150},{"nctId":"NCT06859554","phase":"PHASE4","title":"Efficacy and Safety of GTN vs. Nifedipine in Acute Anal Fissure: A Clinical Trial","status":"COMPLETED","sponsor":"Hafiz Muhammad Hamza","startDate":"2025-03-17","conditions":"Acute Anal Fissure, Anal Pain, Anorectal Disorders","enrollment":110},{"nctId":"NCT06606041","phase":"NA","title":"Comparison of the Efficacy of Dry Needling, Ischemic Compression, and Cross Taping on Masseter Myofascial Pain","status":"ACTIVE_NOT_RECRUITING","sponsor":"University of Coimbra","startDate":"2024-01-10","conditions":"Temporomandibular Joint Disorders, Myofascial Pain","enrollment":60},{"nctId":"NCT05273346","phase":"NA","title":"TCM Conservative Treatment for the Degenerative Lumbar Spinal Stenosis","status":"ACTIVE_NOT_RECRUITING","sponsor":"Beijing University of Chinese Medicine","startDate":"2022-09-01","conditions":"Degenerative Lumbar Spinal Stenosis","enrollment":94},{"nctId":"NCT05341180","phase":"PHASE2, PHASE3","title":"Efficacy of Polyethylene Glycol vs Lactulose With Isabgol in Acute Fissure-in-Ano: PEGASIS Trial","status":"COMPLETED","sponsor":"All India Institute of Medical Sciences, Bhubaneswar","startDate":"2022-05-27","conditions":"Anal Fissure, Constipation","enrollment":144},{"nctId":"NCT05040243","phase":"NA","title":"Acupuncture Combined With Yanqing Zhitong Ointment Acupoint Application in Chronic Non-specific Low Back Pain","status":"UNKNOWN","sponsor":"Shanghai University of Traditional Chinese Medicine","startDate":"2021-07-01","conditions":"Non-specific Low Back Pain","enrollment":86},{"nctId":"NCT05411913","phase":"PHASE3","title":"Topical CBD for Musculoskeletal Pain","status":"UNKNOWN","sponsor":"Apothyx, Co.","startDate":"2022-07-01","conditions":"Pain","enrollment":100},{"nctId":"NCT04719559","phase":"NA","title":"Fractional Laser and Steroid Ointment to Improve the Old Scar After Thyroidectomy","status":"COMPLETED","sponsor":"Chang Gung Memorial Hospital","startDate":"2018-03-20","conditions":"Thyroid; 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Used for Localized musculoskeletal pain and minor aches, Arthritis pain relief.","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}