{"id":"padimate-a","rwe":[{"pmid":"646366","year":"1978","title":"Phototoxicity to a sunscreen ingredient. Padimate A.","finding":"","journal":"Archives of dermatology","studyType":"Clinical Study"}],"tags":[{"label":"Padimate A","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"Topical","category":"route"},{"label":"Lotion","category":"form"},{"label":"Active","category":"status"}],"phase":"marketed","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"_sources":{"trials":{"url":"https://clinicaltrials.gov/search?intr=PADIMATE A","method":"api_direct","source":"ClinicalTrials.gov","rawText":"","confidence":1,"sourceType":"ctgov","retrievedAt":"2026-04-20T01:04:15.525865+00:00"},"regulatory.ca":{"url":"","method":"api_direct","source":"Health Canada DPD","rawText":"","confidence":1,"sourceType":"health_canada_dpd","retrievedAt":"2026-04-20T01:04:22.234017+00:00"},"publicationCount":{"url":"https://pubmed.ncbi.nlm.nih.gov/?term=PADIMATE A","method":"api_direct","source":"PubMed/NCBI","rawText":"","confidence":1,"sourceType":"pubmed","retrievedAt":"2026-04-20T01:04:22.954250+00:00"}},"allNames":"spectraban","offLabel":[],"synonyms":["Padimate A","spectraban"],"timeline":[],"brandName":"Spectraban","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"Padimate A","explanation":"","oneSentence":"","technicalDetail":"Padimate A is a small molecule that likely interacts with cellular targets, such as proteins or receptors, to produce its effects. The exact nature of these interactions and the downstream consequences are currently unknown."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/4638","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://clinicaltrials.gov/search?intr=PADIMATE%20A","fields":["trials"],"source":"ClinicalTrials.gov"},{"id":3,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=PADIMATE A","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T08:19:24.829668","_validation":{"fieldsValidated":0,"lastValidatedAt":"2026-04-20T01:04:40.153273+00:00","fieldsConflicting":1,"overallConfidence":0.8},"biosimilars":[],"competitors":[],"genericName":"padimate a","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[{"nctId":"NCT05124899","phase":"NA","title":"Clinical Study to Evaluate the 80-Minute Water Resistant Sun Protection Factor (SPF) of Sunscreen Products","status":"COMPLETED","sponsor":"HALEON","startDate":"2021-11-16","conditions":["Sunscreening Agents"],"enrollment":15,"completionDate":"2021-12-18"},{"nctId":"NCT05109104","phase":"NA","title":"Clinical Study to Evaluate the Sun Protection Factor (SPF) of Three Sunscreen Products","status":"COMPLETED","sponsor":"HALEON","startDate":"2021-11-08","conditions":["Sunscreening Agents"],"enrollment":13,"completionDate":"2021-12-15"},{"nctId":"NCT05085327","phase":"NA","title":"Clinical Study to Evaluate the Sun Protection Factor (SPF) of Sunscreen Products","status":"COMPLETED","sponsor":"HALEON","startDate":"2021-10-19","conditions":["Sunscreening Agents"],"enrollment":11,"completionDate":"2021-11-04"},{"nctId":"NCT02668536","phase":"PHASE1","title":"A Sunscreen Based on Bioadhesive Nanoparticles","status":"COMPLETED","sponsor":"Yale University","startDate":"2017-07-17","conditions":["Melanoma","UV Ray Skin Damage"],"enrollment":13,"completionDate":"2017-08-18"}],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"administration":{"route":"Topical","formulation":"Lotion","formulations":[{"form":"LOTION","route":"TOPICAL","productName":"TECHNIblock ULTRA SUNSCREEN"}]},"crossReferences":{"NDDF":"006423","UNII":"77FU10423X","CHEBI":"CHEBI:136011","INN_ID":"3060","RXNORM":"1363712","UMLSCUI":"C0069936","ChEMBL_ID":"CHEMBL2107071","KEGG_DRUG":"D05334","DRUGBANK_ID":"DB11229","PUBCHEM_CID":"26890","MESH_SUPPLEMENTAL_RECORD_UI":"C014334"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":1,"therapeuticAreas":["Other"],"biosimilarFilings":[],"recentPublications":[{"date":"1978 Apr","pmid":"646366","title":"Phototoxicity to a sunscreen ingredient. Padimate A.","journal":"Archives of dermatology"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"","enrichmentLevel":3,"visitCount":1,"regulatoryByCountry":[{"country_code":"CA","regulator":"Health Canada","status":"approved","approval_date":null,"mah":"","brand_name_local":"","application_number":""},{"country_code":"US","regulator":"FDA","status":"approved","approval_date":null,"mah":null,"brand_name_local":null,"application_number":null}],"trialStats":{"total":0,"withResults":0},"validation":{"fieldsValidated":0,"lastValidatedAt":"2026-04-20T01:04:40.153273+00:00","fieldsConflicting":1,"overallConfidence":0.8},"verificationStatus":"enriching","dataCompleteness":{"mechanism":false,"indications":false,"safety":false,"trials":true,"score":1}}