{"id":"oxycodone-single-compound","safety":{"commonSideEffects":[{"rate":"40-50","effect":"Constipation"},{"rate":"20-30","effect":"Nausea"},{"rate":"15-25","effect":"Dizziness"},{"rate":"15-25","effect":"Drowsiness"},{"rate":"10-15","effect":"Vomiting"},{"rate":"10-15","effect":"Pruritus"},{"rate":"1-5","effect":"Respiratory depression"}]},"_chembl":{"chemblId":"CHEMBL5785050","moleculeType":null,"molecularWeight":"317.39"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Oxycodone is a semi-synthetic opioid agonist that acts primarily on mu (μ) opioid receptors in the brain and spinal cord. By binding to these receptors, it inhibits the release of neurotransmitters involved in pain perception and modulates pain signaling pathways. This results in pain relief and can also produce euphoria, which contributes to its potential for abuse and dependence.","oneSentence":"Oxycodone binds to opioid receptors in the central nervous system to block pain signal transmission and produce analgesia.","_ai_confidence":"high"},"_scrapedAt":"2026-03-27T23:59:23.350Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Moderate to severe acute pain"},{"name":"Moderate to severe chronic pain"}]},"trialDetails":[{"nctId":"NCT01313780","phase":"PHASE4","title":"A Study to Evaluate Efficacy and Safety of Oxycodone/Naloxone Compared to OxyContin in Korean Cancer Patients","status":"COMPLETED","sponsor":"Mundipharma Korea Ltd","startDate":"2011-05","conditions":"Cancer","enrollment":128}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["Oxycontin"],"phase":"marketed","status":"active","brandName":"Oxycodone(single compound)","genericName":"Oxycodone(single compound)","companyName":"Mundipharma Korea Ltd","companyId":"mundipharma-korea-ltd","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Oxycodone binds to opioid receptors in the central nervous system to block pain signal transmission and produce analgesia. Used for Moderate to severe acute pain, Moderate to severe chronic pain.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}