{"id":"oxybuprocaine-fluorescein-sdu","safety":{"commonSideEffects":[{"rate":null,"effect":"Corneal toxicity"}]},"_chembl":{"chemblId":"CHEMBL177756","moleculeType":"Small molecule","molecularWeight":"332.31"},"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"Oxybuprocaine is a local anesthetic that works by blocking sodium channels in nerve fibers, preventing the transmission of pain signals. Fluorescein is a fluorescent dye that stains the corneal endothelium, allowing for visualization of the corneal endothelial cells. The combination of oxybuprocaine and fluorescein is used to assess corneal endothelial function and morphology.","oneSentence":"Oxybuprocaine/fluorescein SDU is a local anesthetic and a fluorescent dye used to visualize the corneal endothelium.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T01:25:05.971Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Assessment of corneal endothelial function and morphology"}]},"trialDetails":[{"nctId":"NCT07230548","phase":"PHASE3","title":"Effect of Four Different Diagnostic Eye Drops on Tear Film Thickness","status":"COMPLETED","sponsor":"Medical University of Vienna","startDate":"2020-06-10","conditions":"Ocular Surface Disease, Tear Film Characteristics","enrollment":20}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"Oxybuprocaine/fluorescein SDU","genericName":"Oxybuprocaine/fluorescein SDU","companyName":"Medical University of Vienna","companyId":"medical-university-of-vienna","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Oxybuprocaine/fluorescein SDU is a local anesthetic and a fluorescent dye used to visualize the corneal endothelium. Used for Assessment of corneal endothelial function and morphology.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}