{"id":"oxiracetam","rwe":[],"tags":[{"label":"oxiracetam","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"N06BX07","category":"atc"},{"label":"Active","category":"status"},{"label":"Central Nervous System Agents","category":"pharmacology"},{"label":"Nootropic Agents","category":"pharmacology"},{"label":"Psychotropic Drugs","category":"pharmacology"}],"phase":"phase_3","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"neuromet","offLabel":[],"synonyms":["oxiracetam","hydroxypiracetam","neuromet"],"timeline":[],"approvals":[],"brandName":"Neuromet","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"oxiracetam","explanation":"Think of it like a key that unlocks the doors to your brain's memory and learning centers. By enhancing the activity of these neurotransmitters, Neuromet helps improve communication between brain cells, leading to better memory, attention, and learning. This can be especially helpful for people with conditions that affect cognitive function, such as Alzheimer's disease or attention deficit hyperactivity disorder (ADHD).","oneSentence":"Neuromet works by enhancing the activity of neurotransmitters in the brain, such as acetylcholine, to improve cognitive function.","technicalDetail":"Neuromet acts as a cholinergic receptor agonist, increasing the release of acetylcholine and modulating glutamatergic activity through AMPA and NMDA receptor interactions, which enhances synaptic plasticity and cognitive function."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/2021","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://clinicaltrials.gov/search?intr=OXIRACETAM","fields":["trials"],"source":"ClinicalTrials.gov"},{"id":3,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=OXIRACETAM","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T15:13:13.725831","biosimilars":[],"competitors":[],"genericName":"oxiracetam","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[{"nctId":"NCT04205565","phase":"PHASE3","title":"Study on Clinical Effectiveness of L-Oxiracetam Injection","status":"UNKNOWN","sponsor":"Nanjing Yoko Biomedical Co., Ltd.","startDate":"2019-09-30","conditions":["Craniocerebral Injury"],"enrollment":591,"completionDate":"2024-10-31"}],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"NDDF":"008270","UNII":"P7U817352G","CHEBI":"CHEBI:134788","INN_ID":"4762","RXNORM":"32645","UMLSCUI":"C0069772","ChEMBL_ID":"CHEMBL36633","KEGG_DRUG":"D07346","DRUGBANK_ID":"DB13601","PUBCHEM_CID":"4626","MESH_SUPPLEMENTAL_RECORD_UI":"C040619"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"pharmacokinetics":{"source":"DrugCentral","halfLife":"7.5 hours","clearance":"1.8 mL/min/kg","bioavailability":"75%","volumeOfDistribution":"0.55 L/kg"},"publicationCount":213,"therapeuticAreas":["Neuroscience"],"atcClassification":{"source":"DrugCentral","atcCode":"N06BX07","allCodes":["N06BX07"]},"biosimilarFilings":[],"recentPublications":[],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Neuromet, also known as OXIRACETAM, is a small molecule oxiracetam drug developed by UCB (originally developed by UCB, current owner is unknown). Its exact target is unknown, but it is believed to work by enhancing cholinergic neurotransmission and modulating glutamatergic activity. Neuromet is not FDA-approved for any indications, and its commercial status is unclear. Key safety considerations include its potential for hepatotoxicity and interactions with other medications. As a result, its use should be carefully monitored.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":true,"score":2}}