{"id":"oxazolam","rwe":[{"pmid":"31655826","year":"2020","title":"Pharmacological Characteristics of Anxiolytics on Acetylcholine-Induced Contractions in Rat Detrusor Smooth Muscle.","finding":"","journal":"Pharmacology","studyType":"Clinical Study"},{"pmid":"26000220","year":"2014","title":"Mexazolam: clinical efficacy and tolerability in the treatment of anxiety.","finding":"","journal":"Neurology and therapy","studyType":"Clinical Study"},{"pmid":"12455808","year":"2002","title":"Utilization of psychotropic drugs in Taiwan: an overview of outpatient sector in 2000.","finding":"","journal":"Zhonghua yi xue za zhi = Chinese medical journal; Free China ed","studyType":"Clinical Study"},{"pmid":"10978650","year":"2000","title":"Screening and determination of benzodiazepines in whole blood using solid-phase extraction and gas chromatography/mass spectrometry.","finding":"","journal":"Forensic science international","studyType":"Clinical Study"},{"pmid":"10022210","year":"1999","title":"Solid-phase microextraction and GC-ECD of benzophenones for detection of benzodiazepines in urine.","finding":"","journal":"Journal of analytical toxicology","studyType":"Clinical Study"}],"tags":[{"label":"oxazolam","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"}],"phase":"phase_2","safety":{"safetySignals":[{"llr":116.996,"date":"","count":19,"signal":"Myopathy","source":"DrugCentral FAERS","actionTaken":"Reported 19 times (LLR=117)"}],"commonSideEffects":[{"effect":"Myopathy","drugRate":"LLR 117","severity":"common"}]},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"hializan","offLabel":[],"synonyms":["oxazolam","hializan","oxazolazepam"],"timeline":[],"approvals":[],"brandName":"Hializan","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"oxazolam","explanation":"Imagine your brain is a city with many different neighborhoods, each with its own unique function. Oxazolam is like a special key that unlocks the doors to certain neighborhoods, allowing the right chemicals to flow in and help calm the city down. This can lead to feelings of relaxation and reduced anxiety.","oneSentence":"Oxazolam is thought to work by enhancing the activity of neurotransmitters in the brain that help regulate anxiety and sleep.","technicalDetail":"Oxazolam is a benzodiazepine receptor agonist, which means it binds to specific receptors in the brain that are involved in the regulation of anxiety and sleep. This binding action enhances the activity of neurotransmitters such as GABA, leading to a calming effect on the nervous system."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/2016","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=OXAZOLAM","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T15:10:06.307914","biosimilars":[],"competitors":[],"genericName":"oxazolam","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"NDDF":"008172","UNII":"1V2WI2NA1C","CHEBI":"CHEBI:31944","INN_ID":"3013","UMLSCUI":"C0069749","ChEMBL_ID":"CHEMBL2104805","KEGG_DRUG":"D01278","DRUGBANK_ID":"DB15491","PUBCHEM_CID":"4617","MESH_SUPPLEMENTAL_RECORD_UI":"C000425"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":29,"therapeuticAreas":["Neuroscience"],"biosimilarFilings":[],"recentPublications":[{"date":"2020","pmid":"31655826","title":"Pharmacological Characteristics of Anxiolytics on Acetylcholine-Induced Contractions in Rat Detrusor Smooth Muscle.","journal":"Pharmacology"},{"date":"2014 Jun","pmid":"26000220","title":"Mexazolam: clinical efficacy and tolerability in the treatment of anxiety.","journal":"Neurology and therapy"},{"date":"2002 Aug","pmid":"12455808","title":"Utilization of psychotropic drugs in Taiwan: an overview of outpatient sector in 2000.","journal":"Zhonghua yi xue za zhi = Chinese medical journal; Free China ed"},{"date":"2000 Sep 11","pmid":"10978650","title":"Screening and determination of benzodiazepines in whole blood using solid-phase extraction and gas chromatography/mass spectrometry.","journal":"Forensic science international"},{"date":"1999 Jan-Feb","pmid":"10022210","title":"Solid-phase microextraction and GC-ECD of benzophenones for detection of benzodiazepines in urine.","journal":"Journal of analytical toxicology"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Hializan is a small molecule with synonyms including HIALIZAN, OXAZOLAM, SERENAL, and TRANQUIT.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":true,"trials":false,"score":2}}