{"id":"ovide-malathion-lotion-0-05","safety":{"commonSideEffects":[{"rate":"null","effect":"Skin irritation"},{"rate":"null","effect":"Dandruff"},{"rate":"null","effect":"Itching"}]},"_chembl":{"chemblId":"CHEMBL1200468","moleculeType":"Small molecule","molecularWeight":"330.36"},"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"Malathion is an organophosphate insecticide that acts as a cholinesterase inhibitor, disrupting the nervous system of lice and ultimately leading to their death. It also has ovicidal properties, killing lice eggs on the scalp.","oneSentence":"Ovide (malathion) lotion works by killing lice and their eggs on the scalp.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T01:24:54.865Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Treatment of head lice infestations"}]},"trialDetails":[{"nctId":"NCT00927407","phase":"PHASE1","title":"Pharmacokinetics of Malathion Gel 0.5% and Malathion 0.5% Lotion (Ovide) in Patients With Head Lice","status":"COMPLETED","sponsor":"Sun Pharmaceutical Industries, Inc.","startDate":"2009-07","conditions":"Pediculosis","enrollment":24},{"nctId":"NCT00244439","phase":"PHASE3","title":"Safety and Efficacy of a Novel Malathion Formulation in the Treatment of Head Lice","status":"COMPLETED","sponsor":"Sun Pharmaceutical Industries, Inc.","startDate":"2005-12","conditions":"Lice Infestations","enrollment":360}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"Ovide (malathion) lotion 0.05%","genericName":"Ovide (malathion) lotion 0.05%","companyName":"Sun Pharmaceutical Industries, Inc.","companyId":"sun-pharmaceutical-industries-inc","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Ovide (malathion) lotion works by killing lice and their eggs on the scalp. Used for Treatment of head lice infestations.","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}