{"id":"ormeloxifene","rwe":[],"tags":[{"label":"ormeloxifene","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"G03XC04","category":"atc"},{"label":"Active","category":"status"},{"label":"Contraceptive Agents","category":"pharmacology"},{"label":"Contraceptive Agents, Female","category":"pharmacology"},{"label":"Contraceptives, Postcoital, Synthetic","category":"pharmacology"},{"label":"Estrogen Antagonists","category":"pharmacology"},{"label":"Hormone Antagonists","category":"pharmacology"},{"label":"Reproductive Control Agents","category":"pharmacology"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"centron","offLabel":[],"synonyms":["centchroman","ormeloxifene","ormeloxifen","centron"],"timeline":[],"approvals":[],"brandName":"Centron","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"ormeloxifene","explanation":"Imagine your body has locks on the cells that grow and multiply. Centron is a key that fits into these locks, but instead of unlocking the cells, it blocks them from being opened by estrogen. This can help to slow down the growth of certain cells that might be causing problems.","oneSentence":"Centron works by binding to estrogen receptors in the body, which can help to reduce the growth of certain cells.","technicalDetail":"Centron acts as a selective estrogen receptor modulator (SERM), binding to estrogen receptors and influencing gene expression to exert its therapeutic effects."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/570","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=ORMELOXIFENE","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T15:08:52.442001","biosimilars":[],"competitors":[{"drugName":"raloxifene","drugSlug":"raloxifene","fdaApproval":"1997-12-09","genericCount":8,"patentStatus":"Off-patent — generic available","relationship":"same-class"},{"drugName":"bazedoxifene","drugSlug":"bazedoxifene","fdaApproval":"2013-10-03","relationship":"same-class"},{"drugName":"ospemifene","drugSlug":"ospemifene","fdaApproval":"2013-02-26","patentExpiry":"Jul 9, 2028","patentStatus":"Patent protected","relationship":"same-class"}],"genericName":"ormeloxifene","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[{"drugId":"raloxifene","brandName":"raloxifene","genericName":"raloxifene","approvalYear":"1997","relationship":"same-class"},{"drugId":"bazedoxifene","brandName":"bazedoxifene","genericName":"bazedoxifene","approvalYear":"2013","relationship":"same-class"},{"drugId":"ospemifene","brandName":"ospemifene","genericName":"ospemifene","approvalYear":"2013","relationship":"same-class"}],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"UNII":"44AXY5VE90","CHEBI":"CHEBI:135742","INN_ID":"7100","UMLSCUI":"C0007665","ChEMBL_ID":"CHEMBL154126","KEGG_DRUG":"D08301","DRUGBANK_ID":"DB13310","PUBCHEM_CID":"35805","SNOMEDCT_US":"1187476007","MESH_DESCRIPTOR_UI":"D002486","MESH_SUPPLEMENTAL_RECORD_UI":"C508548"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":0,"therapeuticAreas":["Other"],"atcClassification":{"source":"DrugCentral","atcCode":"G03XC04","allCodes":["G03XC04"]},"biosimilarFilings":[],"recentPublications":[],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Centron is a small molecule. It is also known by the synonyms Centchroman, Centchroman, Centron, Ormeloxifene, Ormeloxifene, and Ormeloxifeno.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}