{"id":"orange-peel-fermentation","safety":{"commonSideEffects":[]},"_chembl":{"chemblId":"CHEMBL2107916","moleculeType":"Unknown"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Fermentation of orange peel by microorganisms generates metabolites including polyphenols, flavonoids, and organic acids that may exert anti-inflammatory and antioxidant effects. The exact molecular mechanisms remain incompletely characterized, but fermented orange peel extracts have demonstrated bioactivity in preclinical models. Clinical applications appear focused on functional food or nutraceutical use rather than a defined pharmaceutical mechanism.","oneSentence":"Orange peel fermentation produces bioactive compounds with potential anti-inflammatory and antioxidant properties through microbial fermentation processes.","_ai_confidence":"low"},"_scrapedAt":"2026-03-27T23:58:54.831Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Functional food ingredient (specific clinical indications not well-defined in published literature)"}]},"trialDetails":[{"nctId":"NCT04496895","phase":"NA","title":"The Evaluation of Orange Peel Fermentation on Body Fat Lowering Efficacy in Adults","status":"RECRUITING","sponsor":"TCI Co., Ltd.","startDate":"2022-11-12","conditions":"Overweight, Fatty Liver Disease","enrollment":124},{"nctId":"NCT04910646","phase":"PHASE4","title":"The Evaluation of Orange Peel Fermentation on Body Fat Lowering Efficacy in Adults","status":"UNKNOWN","sponsor":"National Taiwan University Hospital","startDate":"2021-06-15","conditions":"Fat-lowering","enrollment":124}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"orange peel fermentation","genericName":"orange peel fermentation","companyName":"National Taiwan University Hospital","companyId":"national-taiwan-university-hospital","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Orange peel fermentation produces bioactive compounds with potential anti-inflammatory and antioxidant properties through microbial fermentation processes. Used for Functional food ingredient (specific clinical indications not well-defined in published literature).","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":2,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":false,"trials":true,"score":3}}