{"id":"oral-sedatives-with-or-without-analgesia","safety":{"commonSideEffects":[{"rate":null,"effect":"Respiratory depression"},{"rate":null,"effect":"Drowsiness"},{"rate":null,"effect":"Dizziness"},{"rate":null,"effect":"Nausea"},{"rate":null,"effect":"Dependence/tolerance"}]},"_chembl":{"chemblId":"CHEMBL2108778","moleculeType":"Vaccine component"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"This category encompasses oral medications that act on the central nervous system through various mechanisms (e.g., GABAergic potentiation, opioid receptor agonism, or other CNS depressants) to induce sedation and potentially analgesia. The specific molecular targets depend on the individual agent(s) included in the formulation, which is not specified here.","oneSentence":"Oral sedatives with or without analgesia depress the central nervous system to reduce consciousness and/or pain perception.","_ai_confidence":"low"},"_scrapedAt":"2026-03-27T23:58:54.175Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Sedation (with or without analgesia) for procedural or clinical use"}]},"trialDetails":[{"nctId":"NCT05525325","phase":"NA","title":"Mode of Sedation During Endovascular Treatment of Vertebrobasilar Stroke","status":"RECRUITING","sponsor":"University Hospital Heidelberg","startDate":"2022-10-01","conditions":"Stroke Thrombectomy","enrollment":128},{"nctId":"NCT05658692","phase":"PHASE4","title":"Platform Adaptive Embedded Trial for Acute Respiratory Distress Syndrome","status":"UNKNOWN","sponsor":"Second Affiliated Hospital, School of Medicine, Zhejiang University","startDate":"2022-10-01","conditions":"Acute Respiratory Distress Syndrome","enrollment":1000},{"nctId":"NCT04346095","phase":"PHASE4","title":"Oral Sedation in Vitreoretinal Surgery","status":"UNKNOWN","sponsor":"Rocky Vista University, LLC","startDate":"2020-06","conditions":"Macular Holes, Intraocular Lens Opacification, Vitrectomy","enrollment":80}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"Oral Sedatives with or Without Analgesia","genericName":"Oral Sedatives with or Without Analgesia","companyName":"Rocky Vista University, LLC","companyId":"rocky-vista-university-llc","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Oral sedatives with or without analgesia depress the central nervous system to reduce consciousness, anxiety, and/or pain sensation. Used for Sedation and anxiolysis (with or without analgesia), Procedural sedation.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}