{"id":"oral-maalox-mylanta","safety":{"commonSideEffects":[{"rate":null,"effect":"Constipation (aluminum hydroxide)"},{"rate":null,"effect":"Diarrhea (magnesium hydroxide)"},{"rate":null,"effect":"Nausea"},{"rate":null,"effect":"Abdominal cramping"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Aluminum hydroxide and magnesium hydroxide are antacids that directly neutralize hydrochloric acid in the stomach, raising gastric pH and reducing acid-related irritation. Simethicone is an antifoaming agent that reduces gas bubbles in the gastrointestinal tract, alleviating bloating and discomfort associated with acid reflux and indigestion.","oneSentence":"Maalox/Mylanta neutralizes gastric acid and reduces acid reflux symptoms through a combination of aluminum hydroxide, magnesium hydroxide, and simethicone.","_ai_confidence":"high"},"_scrapedAt":"2026-03-27T23:58:47.795Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Heartburn and acid indigestion"},{"name":"Gastroesophageal reflux disease (GERD) symptom relief"},{"name":"Bloating and gas associated with indigestion"}]},"trialDetails":[{"nctId":"NCT06241183","phase":"PHASE4","title":"Famotidine and Antacids for Treatment of Dyspepsia","status":"RECRUITING","sponsor":"Stony Brook University","startDate":"2023-11-09","conditions":"Dyspepsia, GERD, Acid Reflux","enrollment":80},{"nctId":"NCT06819033","phase":"PHASE4","title":"Effects of Photobiomodulation (PBM) on Pain After Presentation of Aphthous Ulcers in Pediatric Dental Patients","status":"RECRUITING","sponsor":"The University of Texas Health Science Center, Houston","startDate":"2025-03-10","conditions":"Aphthous Ulcer","enrollment":30},{"nctId":"NCT05109390","phase":"PHASE1","title":"A Study of the Drug Interactions Between Danicopan and Cyclosporine, Tacrolimus, Antacids, and Omeprazole in Healthy Adults","status":"COMPLETED","sponsor":"Alexion Pharmaceuticals, Inc.","startDate":"2018-07-27","conditions":"Healthy","enrollment":72},{"nctId":"NCT04368585","phase":"PHASE1","title":"Study to Examine the Effect of Antacid and Omeprazole on the Single-Dose Pharmacokinetics of Tebipenem Pivoxil Hydrobromide (TBPM-PI-HBr) in Healthy Adult Subjects","status":"COMPLETED","sponsor":"Spero Therapeutics","startDate":"2020-07-01","conditions":"Healthy Volunteers","enrollment":20},{"nctId":"NCT00944307","phase":"PHASE1","title":"Effect of Antacids on the Pharmacokinetics of Raltegravir","status":"COMPLETED","sponsor":"University of Colorado, Denver","startDate":"2009-07","conditions":"HIV Infections","enrollment":17},{"nctId":"NCT01622673","phase":"PHASE1","title":"A Pharmacokinetic Study to Evaluate the Effect of Antacids on Raltegravir (MK-0518) in HIV-Infected Participants (MK-0518-247)","status":"COMPLETED","sponsor":"Merck Sharp & Dohme LLC","startDate":"2012-06","conditions":"HIV Infections","enrollment":27}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":1,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["Antacid"],"phase":"marketed","status":"active","brandName":"Oral Maalox/ Mylanta","genericName":"Oral Maalox/ Mylanta","companyName":"Stony Brook University","companyId":"stony-brook-university","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Maalox/Mylanta neutralizes gastric acid and reduces acid reflux symptoms through a combination of aluminum hydroxide, magnesium hydroxide, and simethicone. Used for Heartburn and acid indigestion, Gastroesophageal reflux disease (GERD) symptom relief, Upset stomach and bloating.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}