{"id":"oral-dienogest","safety":{"commonSideEffects":[{"rate":"10-20","effect":"Headache"},{"rate":"10-15","effect":"Breast pain/tenderness"},{"rate":"20-40","effect":"Irregular bleeding/amenorrhea"},{"rate":"5-10","effect":"Nausea"},{"rate":"5-10","effect":"Mood changes/depression"},{"rate":"5-10","effect":"Weight gain"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Dienogest acts as a selective progestin receptor agonist with high affinity for progesterone receptors, particularly in endometrial tissue. It inhibits the hypothalamic-pituitary-ovarian axis to suppress ovulation and causes decidualization and atrophy of ectopic endometrial lesions. 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