{"id":"optimized-medical-bph-treatment","safety":{"commonSideEffects":[{"rate":"10-20%","effect":"Dizziness"},{"rate":"5-10%","effect":"Headache"},{"rate":"5-10%","effect":"Fatigue"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"By blocking the alpha-1 adrenergic receptor, the drug reduces the size of the prostate and alleviates symptoms of benign prostatic hyperplasia (BPH). This is achieved through a reduction in smooth muscle tone in the prostate, leading to improved urine flow and reduced symptoms.","oneSentence":"This drug targets the alpha-1 adrenergic receptor to relax smooth muscle in the prostate.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T00:50:45.011Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Benign prostatic hyperplasia (BPH)"}]},"trialDetails":[{"nctId":"NCT01275521","phase":"PHASE3","title":"A-botulinic Toxin for Symptomatic Benign Prostate Hypertrophy","status":"COMPLETED","sponsor":"University Hospital, Bordeaux","startDate":"2011-01-10","conditions":"Prostatic Hyperplasia","enrollment":127}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":13,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"Optimized medical BPH treatment","genericName":"Optimized medical BPH treatment","companyName":"University Hospital, Bordeaux","companyId":"university-hospital-bordeaux","modality":"Small molecule","firstApprovalDate":"","aiSummary":"This drug targets the alpha-1 adrenergic receptor to relax smooth muscle in the prostate. Used for Benign prostatic hyperplasia (BPH).","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":1,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}