{"id":"ondansetron-oral-soluble-pellicles","safety":{"commonSideEffects":[{"rate":"10-20%","effect":"Headache"},{"rate":"5-10%","effect":"Dizziness"},{"rate":"5-10%","effect":"Constipation"},{"rate":"5-10%","effect":"Diarrhea"},{"rate":"5-10%","effect":"Fatigue"}]},"_chembl":{"chemblId":"CHEMBL1201111","moleculeType":"Small molecule","molecularWeight":"329.83"},"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"This is achieved by selectively antagonizing the 5-HT3 receptor, a subtype of serotonin receptor found in the gastrointestinal tract and the central nervous system. By blocking these receptors, ondansetron reduces the vomiting reflex and alleviates nausea.","oneSentence":"Ondansetron works by blocking serotonin receptors in the body, which helps to reduce nausea and vomiting.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T00:50:36.894Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Prevention of nausea and vomiting caused by cancer chemotherapy"},{"name":"Prevention of nausea and vomiting caused by radiation therapy"}]},"trialDetails":[{"nctId":"NCT06282211","phase":"PHASE3","title":"the Efficacy and Safety of Ondansetron Oral Soluble Pellicles","status":"UNKNOWN","sponsor":"The First Affiliated Hospital of Xinxiang Medical College","startDate":"2024-02-20","conditions":"Nausea and Vomiting","enrollment":184}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["Aiqisu"],"phase":"phase_3","status":"active","brandName":"Ondansetron Oral Soluble Pellicles","genericName":"Ondansetron Oral Soluble Pellicles","companyName":"The First Affiliated Hospital of Xinxiang Medical College","companyId":"the-first-affiliated-hospital-of-xinxiang-medical-college","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Ondansetron works by blocking serotonin receptors in the body, which helps to reduce nausea and vomiting. Used for Prevention of nausea and vomiting caused by cancer chemotherapy, Prevention of nausea and vomiting caused by radiation therapy.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}