{"id":"omega-3-fatty-acids-omegaven","safety":{"commonSideEffects":[{"rate":null,"effect":"Gastrointestinal upset (nausea, dyspepsia)"},{"rate":null,"effect":"Bleeding or increased bleeding tendency"},{"rate":null,"effect":"Fishy aftertaste"},{"rate":null,"effect":"Hypersensitivity reactions (with IV formulation)"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Omega-3 fatty acids (EPA and DHA) incorporate into cell membranes and displace omega-6 arachidonic acid, reducing production of pro-inflammatory eicosanoids. They also activate G-protein coupled receptors and nuclear receptors (PPAR-γ, LXR) that suppress inflammatory gene expression. 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