{"id":"olopatadine-olo","safety":{"commonSideEffects":[{"rate":null,"effect":"Headache"},{"rate":null,"effect":"Ocular irritation (for ophthalmic formulation)"},{"rate":null,"effect":"Somnolence"},{"rate":null,"effect":"Bitter taste (for nasal formulation)"}]},"_chembl":null,"_dailymed":{"setId":"3e86783f-0001-625f-e063-6294a90acd20","title":"OLOPATADINE HYDROCHLORIDE SOLUTION [BLUEPOINT LABORATORIES]"},"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Olopatadine works by competitively antagonizing H1 histamine receptors on target tissues, preventing histamine-induced allergic symptoms. Additionally, it stabilizes mast cells, reducing the release of inflammatory mediators. This dual mechanism makes it effective for allergic conditions, particularly allergic conjunctivitis and allergic rhinitis.","oneSentence":"Olopatadine is a selective H1-receptor antagonist and mast cell stabilizer that blocks histamine-mediated allergic responses.","_ai_confidence":"high"},"_scrapedAt":"2026-03-27T23:58:11.932Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Allergic conjunctivitis"},{"name":"Allergic rhinitis"}]},"trialDetails":[{"nctId":"NCT01007253","phase":"PHASE4","title":"Effect of Veramyst and Olopatadine 0.2% Opthalmic Solution on Allergy Symptoms","status":"COMPLETED","sponsor":"University of Chicago","startDate":"2009-11","conditions":"Seasonal Allergic Rhinitis","enrollment":21}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":24,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["Olopatadine 0.2% ophthalmic solution"],"phase":"marketed","status":"active","brandName":"olopatadine (OLO)","genericName":"olopatadine (OLO)","companyName":"University of Chicago","companyId":"university-of-chicago","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Olopatadine is a selective H1-receptor antagonist and mast cell stabilizer that blocks histamine-mediated allergic responses. Used for Allergic conjunctivitis, Allergic rhinitis.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}