{"id":"olive-oil","_fda":{"id":"32550ac9-fd50-25ef-e063-6294a90a5dc7","set_id":"32550ac9-fd4f-25ef-e063-6294a90a5dc7","openfda":{"nui":["N0000191261","M0012553"],"unii":["2ZA36H0S2V","6UYK2W1W1E","LZO6K1506A","9BYZ11E7BF"],"route":["TOPICAL"],"spl_id":["32550ac9-fd50-25ef-e063-6294a90a5dc7"],"brand_name":["All-Purpose Salve"],"spl_set_id":["32550ac9-fd4f-25ef-e063-6294a90a5dc7"],"package_ndc":["85522-001-01"],"product_ndc":["85522-001"],"generic_name":["OLIVE OIL, RICE BRAN OIL, NATURAL BEESWAX, BITTER LEAF EXTRACT"],"product_type":["HUMAN OTC DRUG"],"pharm_class_cs":["Lipids [CS]"],"substance_name":["BEESWAX","OLIVE OIL","RICE BRAN OIL","VERNONIA APPENDICULATA WHOLE"],"pharm_class_epc":["Lipid Emulsion [EPC]"],"manufacturer_name":["BIOCARE PLUS INTERNATIONAL LIMITED"],"application_number":["505G(a)(3)"],"is_original_packager":[true]},"purpose":["Moisturizing the skin"],"version":"1","stop_use":["Stop use and ask a doctor ifcondition worscnse or syptomslast more than 7 days or clear up and occur again with in a few doys,"],"warnings":["For cxternal use only."],"when_using":["When using this product do not get into eye."],"effective_time":"20250409","active_ingredient":["Olive Oil Rice Bran Oil Natural Beeswax Bitter Leaf Extract"],"inactive_ingredient":["Natural Cocoa Butter Vitamin E Acetate Menthol Natural Lemon Essentail Oil"],"indications_and_usage":["Use: Temporarily protects and helps relieve minor sk¡n iritationand itching due to rashes and eczema"],"dosage_and_administration":["Directions: Apply as needed,"],"spl_product_data_elements":["All-Purpose Salve Olive Oil, Rice Bran Oil, Natural Beeswax, Bitter Leaf Extract BEESWAX BEESWAX VERNONIA APPENDICULATA WHOLE VERNONIA APPENDICULATA WHOLE LEMON OIL MENTHOL OLIVE OIL OLIVE OIL RICE BRAN OIL RICE BRAN OIL COCOA BUTTER .ALPHA.-TOCOPHEROL ACETATE"],"keep_out_of_reach_of_children":["KEEP OUT OF REACH OF CHILDREN SECTION"],"package_label_principal_display_panel":["label1"]},"safety":{"boxedWarnings":[],"safetySignals":[{"date":"","signal":"LIVER FUNCTION TEST INCREASED","source":"FDA FAERS","actionTaken":"5 reports"},{"date":"","signal":"FLUSHING","source":"FDA FAERS","actionTaken":"4 reports"},{"date":"","signal":"NAUSEA","source":"FDA FAERS","actionTaken":"4 reports"},{"date":"","signal":"DRUG INEFFECTIVE","source":"FDA FAERS","actionTaken":"3 reports"},{"date":"","signal":"PRURITUS","source":"FDA FAERS","actionTaken":"3 reports"},{"date":"","signal":"URTICARIA","source":"FDA FAERS","actionTaken":"3 reports"},{"date":"","signal":"BACK PAIN","source":"FDA FAERS","actionTaken":"2 reports"},{"date":"","signal":"BLOOD ALKALINE PHOSPHATASE INCREASED","source":"FDA FAERS","actionTaken":"2 reports"},{"date":"","signal":"DEATH","source":"FDA FAERS","actionTaken":"2 reports"},{"date":"","signal":"DYSPNOEA","source":"FDA FAERS","actionTaken":"2 reports"}]},"_chembl":null,"_sources":{"trials":{"url":"https://clinicaltrials.gov/search?intr=OLIVE OIL","method":"api_direct","source":"ClinicalTrials.gov","rawText":"","confidence":1,"sourceType":"ctgov","retrievedAt":"2026-04-20T03:11:46.608403+00:00"},"regulatory.ca":{"url":"","method":"api_direct","source":"Health Canada DPD","rawText":"","confidence":1,"sourceType":"health_canada_dpd","retrievedAt":"2026-04-20T03:11:53.855470+00:00"},"regulatory.us":{"url":"","method":"api_direct","source":"FDA Drugs@FDA","rawText":"","confidence":1,"sourceType":"fda_drugsfda","retrievedAt":"2026-04-20T03:11:45.237130+00:00"},"publicationCount":{"url":"https://pubmed.ncbi.nlm.nih.gov/?term=OLIVE OIL","method":"api_direct","source":"PubMed/NCBI","rawText":"","confidence":1,"sourceType":"pubmed","retrievedAt":"2026-04-20T03:11:54.711411+00:00"},"mechanism.drugClass":{"url":"https://api.fda.gov/drug/label.json","method":"deterministic","source":"FDA Label (EPC)","rawText":"","confidence":1,"sourceType":"fda_label","retrievedAt":"2026-04-20T03:11:44.123959+00:00"},"administration.route":{"url":"","method":"deterministic","source":"FDA Label","rawText":"","confidence":1,"sourceType":"fda_label","retrievedAt":"2026-04-20T03:11:44.124026+00:00"},"indications.approved":{"url":"","method":"ai_extraction","source":"FDA Label + AI","aiModel":"featherless","rawText":"","confidence":0.9,"sourceType":"fda_label","retrievedAt":"2026-04-20T03:12:01.973671+00:00"},"safety.boxedWarnings":{"url":"","method":"deterministic","source":"FDA Label (no boxed warning)","rawText":"","confidence":1,"sourceType":"fda_label","retrievedAt":"2026-04-20T03:11:44.124041+00:00"},"safety.safetySignals":{"url":"https://api.fda.gov/drug/event.json","method":"api_direct","source":"FDA FAERS","rawText":"","confidence":1,"sourceType":"fda_faers","retrievedAt":"2026-04-20T03:11:56.402886+00:00"},"crossReferences.chemblId":{"url":"https://www.ebi.ac.uk/chembl/compound_report_card/CHEMBL2107910/","method":"api_direct","source":"ChEMBL (EMBL-EBI)","rawText":"","confidence":1,"sourceType":"chembl","retrievedAt":"2026-04-20T03:11:55.188561+00:00"},"regulatory.fda_application":{"url":"","method":"deterministic","source":"FDA Label","rawText":"505G(a)(3)","confidence":1,"sourceType":"fda_label","retrievedAt":"2026-04-20T03:11:44.124051+00:00"}},"_dailymed":{"setId":"42f8c2fb-a4e6-9416-e063-6294a90af9d5","title":"PLANEAIRE HANDS LEMON OLIVE OIL HAND SANITIZER (ETHANOL HAND SANITIZER) LOTION [EVERYWHEREAIRE LLC]"},"mechanism":{"drugClass":"Lipid Emulsion [EPC]"},"_scrapedAt":"2026-03-27T23:35:16.677Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"_validation":{"fieldsValidated":1,"lastValidatedAt":"2026-04-20T03:12:02.240154+00:00","fieldsConflicting":0,"overallConfidence":0.95},"indications":{"approved":[{"id":"olive-oil-minor-skin-irritation-and-itch","name":"Minor skin irritation and itching relief","dosing":null,"approvals":[],"diseaseId":"","eligibility":"Not specified","pivotalTrial":null,"restrictions":[],"patientPopulation":"Not specified","diagnosticRequired":null,"brandNameForIndication":""}]},"trialDetails":[{"nctId":"NCT05701657","phase":"NA","title":"Nutrition for Precision Health, Powered by the All of Us","status":"RECRUITING","sponsor":"RTI International","startDate":"2023-04-14","conditions":"Nutrition, Health, Dietary Habits","enrollment":8000},{"nctId":"NCT07490782","phase":"NA","title":"Nutritional Intervention for College Students With Depression","status":"RECRUITING","sponsor":"University of California, San Diego","startDate":"2026-03","conditions":"Depression - Major Depressive Disorder","enrollment":30},{"nctId":"NCT05469997","phase":"NA","title":"Ketogenic Diet Interventions in Parkinson's Disease: Safeguarding the Gut Microbiome","status":"COMPLETED","sponsor":"University of British Columbia","startDate":"2023-03-01","conditions":"Parkinson Disease","enrollment":52},{"nctId":"NCT07356440","phase":"NA","title":"Effect of the Consumption of Cookies Enriched With Plant Proteins and of a Vitamin D Supplement on the Progression of Sarcopenia in the Elderly","status":"ENROLLING_BY_INVITATION","sponsor":"University of Udine","startDate":"2025-12-01","conditions":"Sarcopenia in Elderly, Sarcopenia, Nutritional Intervention","enrollment":74},{"nctId":"NCT03372733","phase":"PHASE2","title":"Dietary Omega-7 Palmitoleic Acid-Rich Oil on Lipoprotein Metabolism and Satiety in Adults","status":"RECRUITING","sponsor":"National Heart, Lung, and Blood Institute (NHLBI)","startDate":"2018-07-31","conditions":"Cardiovascular Disease","enrollment":110},{"nctId":"NCT07478588","phase":"NA","title":"Structured Physical Activity Intervention in Patients With MASLD Receiving a Mediterranean Diet","status":"COMPLETED","sponsor":"Fundación Pública Andaluza para la gestión de la Investigación en Sevilla","startDate":"2022-06-01","conditions":"MASLD","enrollment":96},{"nctId":"NCT07184268","phase":"NA","title":"Clinical Efficacy of NST With Adjunctive Local Delivery of Ozonated Olive Versus Curcumin Gel in Stage II Grade B Periodontitis.","status":"COMPLETED","sponsor":"Cairo University","startDate":"2025-11-02","conditions":"Periodontitis, Adult","enrollment":40},{"nctId":"NCT04031508","phase":"PHASE2","title":"Effect of a Parenteral Emulsion With Omega3 on Neonates With PPHN and CDH","status":"ENROLLING_BY_INVITATION","sponsor":"Coordinación de Investigación en Salud, Mexico","startDate":"2019-08-12","conditions":"Pulmonary Hypertension of Newborn, Diaphragm Defect","enrollment":40},{"nctId":"NCT07477236","phase":"NA","title":"MyVitalC: Sleep and Everyday Headache Management","status":"RECRUITING","sponsor":"Efforia, Inc","startDate":"2026-01-24","conditions":"Sleep, Headaches","enrollment":100},{"nctId":"NCT06998238","phase":"NA","title":"Evaluating the Influence of Diet-induced Weight Loss on Fat (Adipose) Tissue's Insulin Sensitivity and Testosterone Synthesis in Women With Overweight or Obesity, Insulin Resistance, and Hyperandrogenemia","status":"ACTIVE_NOT_RECRUITING","sponsor":"University of Missouri-Columbia","startDate":"2024-01-07","conditions":"Overweight and Obesity, Hyperandrogenemia, Insulin Resistance","enrollment":8},{"nctId":"NCT07375238","phase":"NA","title":"Effect of Daily Intake of Gazpacho on Semen Quality and Oxidative Stress","status":"RECRUITING","sponsor":"Ginefiv","startDate":"2026-03-02","conditions":"Male Infertility, Oxidative Stress, Subfertility","enrollment":80},{"nctId":"NCT07462871","phase":"NA","title":"Comparative Effects of Carnivore and Mediterranean-style Diets on LDL Aggregation and Cardiometabolic Health","status":"NOT_YET_RECRUITING","sponsor":"Liverpool John Moores University","startDate":"2026-06","conditions":"Atherosclerosis Cardiovascular Disease, Metabolic Syndrome, Dyslipidaemia","enrollment":30},{"nctId":"NCT07456332","phase":"NA","title":"Effect on Body Weight Reduction of a Behavioral Intervention on Lifestyle Using a Digital Nutritional Program in People Living With HIV and Metabolic Dysfunction-associated Steatotic Liver Disease","status":"ENROLLING_BY_INVITATION","sponsor":"Hospital Universitari de Bellvitge","startDate":"2025-04-23","conditions":"Metabolic Dysfunction-Associated Steatotic Liver Disease, People Living With HIV, Life Style","enrollment":116},{"nctId":"NCT07173166","phase":"NA","title":"Non-Pharmacological Interventions for Neurotoxicity in Hematologic Patients Receiving CAR-T Therapy","status":"RECRUITING","sponsor":"Instituto de Investigacion Sanitaria INCLIVA","startDate":"2025-09-30","conditions":"Hematologic Cancer","enrollment":100},{"nctId":"NCT06931977","phase":"NA","title":"Natural Product System and Lifestyle Modification","status":"COMPLETED","sponsor":"dōTERRA International","startDate":"2025-04-29","conditions":"Healthy","enrollment":97},{"nctId":"NCT07445503","phase":"NA","title":"High Phenolic Olive Oil for Enhancing Metabolic Health: a Randomized-controlled Trial in Patients With cEntral Obesity (HOPE)","status":"RECRUITING","sponsor":"University of Peloponnese","startDate":"2025-03-03","conditions":"Adults, Overweight , Obesity, Metabolic Abnormalities","enrollment":80},{"nctId":"NCT07438652","phase":"NA","title":"Effect of Mediterranean vs Paleolithic Diet on RA Activity, Sarcopenia and QOL: 12-Week RCT","status":"RECRUITING","sponsor":"Kasr El Aini Hospital","startDate":"2026-01-17","conditions":"Rheumatoid Arthritis (RA)","enrollment":75},{"nctId":"NCT07440784","phase":"NA","title":"Impact Of Intermittent And Water-Only Fasting On Gene Expression And Tumor Markers In Breast Cancer","status":"ACTIVE_NOT_RECRUITING","sponsor":"Khyber Medical University Peshawar","startDate":"2022-08-01","conditions":"Breast Cancer","enrollment":60},{"nctId":"NCT07412444","phase":"NA","title":"EVOO and Metabolic Liver Health in MASLD","status":"NOT_YET_RECRUITING","sponsor":"Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis","startDate":"2026-04-01","conditions":"MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease, Overweight","enrollment":60},{"nctId":"NCT07422051","phase":"PHASE2","title":"Erythrodiol in Pomace Olive Oil as a Protective Agent Against Atherosclerosis","status":"NOT_YET_RECRUITING","sponsor":"Spanish National Research Council","startDate":"2026-02-21","conditions":"Atherosclerosis Cardiovascular Disease","enrollment":22},{"nctId":"NCT07417891","phase":"NA","title":"Ketogenic Diet to Reduce Osteoarthritis Pain in MCI","status":"NOT_YET_RECRUITING","sponsor":"University of Kansas Medical Center","startDate":"2026-03-01","conditions":"Osteoarthritis (OA) of the Hip, Osteoarthritis (OA) of the Knee, Osteoarthritis (OA) of the Shoulder","enrollment":10},{"nctId":"NCT06245616","phase":"NA","title":"Attenuation of Postprandial Inflammatory Processes in Alzheimer's Disease Patients by Consumption of Pomace Oil","status":"ACTIVE_NOT_RECRUITING","sponsor":"Spanish National Research Council","startDate":"2024-05-01","conditions":"Alzheimer's Disease","enrollment":80},{"nctId":"NCT07385716","phase":"NA","title":"Evaluation of the Effect of Time-Restricted Feeding and Mediterranean Diet Model in Women With Polycystic Ovary Syndrome","status":"RECRUITING","sponsor":"Selcuk University","startDate":"2026-01-02","conditions":"Polycystic Ovary Syndrome","enrollment":62},{"nctId":"NCT07057999","phase":"NA","title":"Investigation of the Effect of the MIND Diet on Disease Symptoms in Patients With MS","status":"COMPLETED","sponsor":"Betul Uner","startDate":"2025-06-16","conditions":"Multiple Sclerosis, Diet Therapy, Body Composition","enrollment":62},{"nctId":"NCT07018986","phase":"NA","title":"The MIND-BC Study: MIND Diet for Breast Cancer Cognition","status":"RECRUITING","sponsor":"H. Lee Moffitt Cancer Center and Research Institute","startDate":"2025-07-09","conditions":"Breast Cancer","enrollment":200},{"nctId":"NCT07275957","phase":"NA","title":"Combined Nutrition and Exercise Interventions in Women With Breast Cancer History","status":"ACTIVE_NOT_RECRUITING","sponsor":"University of Alicante","startDate":"2023-09-01","conditions":"Breast Cancer Survivors","enrollment":120},{"nctId":"NCT04149288","phase":"NA","title":"Olive Oil Polyphenols and Cardiovascular Health Biomarkers","status":"ACTIVE_NOT_RECRUITING","sponsor":"University of California, Davis","startDate":"2021-10-06","conditions":"Healthy, Normal Weight, Overweight","enrollment":44},{"nctId":"NCT02706262","phase":"NA","title":"Complex Effects of Dietary Manipulation on Metabolic Function, Inflammation and Health","status":"ACTIVE_NOT_RECRUITING","sponsor":"Washington University School of Medicine","startDate":"2016-02","conditions":"Obesity, Insulin Resistance","enrollment":180},{"nctId":"NCT07364331","phase":"NA","title":"Omega-3 Fatty Acids, Neuroendocrine and Attention Deficit Hyperactivity Disorder (OMNeADHD)","status":"RECRUITING","sponsor":"China Medical University Hospital","startDate":"2021-09-04","conditions":"ADHD, Children, Adolescents","enrollment":100},{"nctId":"NCT07368114","phase":"PHASE2","title":"Validity of Ozonated Olive Oil Gel Versus Injectable Bone Graft","status":"COMPLETED","sponsor":"Suez Canal University","startDate":"2023-12-10","conditions":"Dental, Implant Osseointegration, Ozone Therapy","enrollment":16},{"nctId":"NCT07363616","phase":"NA","title":"Pilot Test of Five Weight Neutral Interventions to Improve Health Among Adults of Higher Body Weight","status":"RECRUITING","sponsor":"The Miriam Hospital","startDate":"2025-12-31","conditions":"Obesity & Overweight, Cardiometabolic Risk Factors","enrollment":50},{"nctId":"NCT06043531","phase":"NA","title":"Targeting Trimethylamine N-Oxide for Cardiovascular Health In Liver Transplant Recipients","status":"COMPLETED","sponsor":"Virginia Commonwealth University","startDate":"2024-01-18","conditions":"Liver Transplant","enrollment":19},{"nctId":"NCT07348562","phase":"NA","title":"Omega-3, Inflammation in ADHD With AI","status":"COMPLETED","sponsor":"China Medical University Hospital","startDate":"2021-02-01","conditions":"Adhd","enrollment":15},{"nctId":"NCT07344428","phase":"NA","title":"Efficacy and Safety of CDED With Anti-TNF-α Biologics in Crohn's Disease: A Randomized Trial","status":"NOT_YET_RECRUITING","sponsor":"Sixth Affiliated Hospital, Sun Yat-sen University","startDate":"2026-02-01","conditions":"Crohn's Disease；Mucosal Healing；Dietary Intervention","enrollment":185},{"nctId":"NCT05363267","phase":"PHASE1","title":"NF-1, Nutraceutical Intervention","status":"ACTIVE_NOT_RECRUITING","sponsor":"Masonic Cancer Center, University of Minnesota","startDate":"2022-07-06","conditions":"Neurofibromatosis 1","enrollment":23},{"nctId":"NCT07034794","phase":"NA","title":"A Clinical Trial to Examine Lysoveta on Cognitive Function in Healthy Adults With Self-perceived Memory Problems","status":"RECRUITING","sponsor":"Aker BioMarine Human Ingredients AS","startDate":"2025-12-06","conditions":"Healthy, Memory Problems","enrollment":138},{"nctId":"NCT07321431","phase":"NA","title":"The Optimal Measurement Time for the New Gallbladder Function Assessment Method","status":"RECRUITING","sponsor":"Hepatopancreatobiliary Surgery Institute of Gansu Province","startDate":"2026-01-07","conditions":"Gallbladder; Functional Disturbance","enrollment":120},{"nctId":"NCT07326891","phase":"NA","title":"Effects of a Mediterranean Diet With Cycling and Rowing Exercise on Blood Sugar in Women With Prediabetes","status":"ENROLLING_BY_INVITATION","sponsor":"Begüm Yücesoy Güneysu","startDate":"2025-12-15","conditions":"Prediabetes","enrollment":30},{"nctId":"NCT05635929","phase":"NA","title":"Effect of a Novel Topical Composition on the Incidence of Severe Oral Mucositis in Head & Neck Cancer Radiated Patients and Quality of Life Assessed by PROMs.","status":"COMPLETED","sponsor":"Mucosa Innovations, S.L.","startDate":"2022-10-11","conditions":"Oral Mucositis, Quality of Life, Mucositis","enrollment":63},{"nctId":"NCT05465252","phase":"NA","title":"Effect of Omega-3 Fatty Acid Supplementation on Dry-AMD Progression","status":"RECRUITING","sponsor":"Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine","startDate":"2025-10-17","conditions":"Age-Related Macular Degeneration","enrollment":24},{"nctId":"NCT07314177","phase":"NA","title":"Effects of Three Dietary Strategies on Body Composition and Metabolic Health in Adults With Overweight or Obesity","status":"COMPLETED","sponsor":"Consorcio Centro de Investigación Biomédica en Red (CIBER)","startDate":"2024-09-08","conditions":"Overweight (BMI > 25), Obesity &Amp; Overweight, Metabolic Syndrome (MetS)","enrollment":45},{"nctId":"NCT07269093","phase":"NA","title":"Efficacy in Preventing Hypertrophic Scars: A Randomised Controlled Trial Comparing Chitosan Cream, Silicone Gel & Olive Oil","status":"RECRUITING","sponsor":"Universiti Sains Malaysia","startDate":"2025-12-21","conditions":"Hypertrophic Scars","enrollment":120},{"nctId":"NCT07312435","phase":"NA","title":"B-vitamins and Omega-3 Fatty Acids and Biomarkers of Brain Atrophy.","status":"RECRUITING","sponsor":"University of Oslo","startDate":"2025-09-01","conditions":"Dementia, Cognitive Function","enrollment":96},{"nctId":"NCT06800352","phase":"NA","title":"The Effect of Olive Oil and Centaury Oil on Rash","status":"COMPLETED","sponsor":"Harran University","startDate":"2024-12-30","conditions":"Diaper Dermatitis","enrollment":45},{"nctId":"NCT07308483","phase":"NA","title":"Ketogenic Approach to Restore Muscle in Older Patients With Community-Acquired Pneumonia - KARMA-P Trial","status":"NOT_YET_RECRUITING","sponsor":"University of Alabama at Birmingham","startDate":"2026-06-01","conditions":"Pneumonia","enrollment":30},{"nctId":"NCT06474546","phase":"NA","title":"Feasibility of a Diet Intervention for Juvenile Arthritis","status":"RECRUITING","sponsor":"The Hospital for Sick Children","startDate":"2025-04-07","conditions":"Arthritis, Juvenile, Arthritis, Childhood, Juvenile Idiopathic Arthritis","enrollment":54},{"nctId":"NCT05485402","phase":"NA","title":"Dietary Strategy to Tackle Sarcopenia in Early Elderly Subjects (FOOP-Sarc)","status":"COMPLETED","sponsor":"University Rovira i Virgili","startDate":"2022-09-01","conditions":"Sarcopenia","enrollment":39},{"nctId":"NCT07294963","phase":"NA","title":"Impact of Lifestyle Interventions on Cognitive Decline in Non-alcoholic Fatty Liver Disease","status":"RECRUITING","sponsor":"Khyber Medical University Peshawar","startDate":"2025-10-01","conditions":"Non-Alcoholic Fatty Liver Disease, Neurocognitive Disorders","enrollment":45},{"nctId":"NCT07293013","phase":"NA","title":"A Study on the Effectiveness of Olive Oil Mouthwash in Alleviating Chemoradiotherapy-induced Oral Mucositis in Patients With Head and Neck Cancer.","status":"RECRUITING","sponsor":"Chiayi Christian Hospital","startDate":"2022-12-04","conditions":"Oral Mucositis in Head and Neck Cancer, Chemo-radiotherapy","enrollment":120},{"nctId":"NCT06933095","phase":"NA","title":"Optimizing CNS DHA Delivery in Elderly Adults at Risk for Dementia","status":"RECRUITING","sponsor":"University of Cincinnati","startDate":"2024-09-15","conditions":"Eldery People, Cognitive Decline, Memory Decline","enrollment":153},{"nctId":"NCT04431700","phase":"NA","title":"Study of Dietary Composition in Crohn's Disease","status":"TERMINATED","sponsor":"University of California, Los Angeles","startDate":"2020-10-05","conditions":"Inflammatory Bowel Diseases, Crohn Disease","enrollment":28},{"nctId":"NCT06001632","phase":"NA","title":"Changes in Muscle Strength, Inflammatory Markers, and Body Composition in Response to Alternate Day Fasting Combined With Krill Oil Supplementation in Adults With Overweight and Obesity","status":"COMPLETED","sponsor":"University of Glasgow","startDate":"2022-03-28","conditions":"Obesity Associated Disorder","enrollment":50},{"nctId":"NCT07287696","phase":"NA","title":"Effect of Siwan Sand Therapy on Pulmonary Functions of Rheumatoid Arthritis Patients","status":"COMPLETED","sponsor":"Ahram Canadian University","startDate":"2016-06","conditions":"Rheumatoid Arthritis (RA","enrollment":15},{"nctId":"NCT04417595","phase":"PHASE2","title":"Omega-3 Fatty Acids for Smoking Cessation in Pregnancy","status":"ACTIVE_NOT_RECRUITING","sponsor":"Vanderbilt University Medical Center","startDate":"2020-11-10","conditions":"Preterm Labor, Tobacco Use Disorder","enrollment":400},{"nctId":"NCT06682390","phase":"NA","title":"Role of Race in Nutritional Approach in Men on ADT","status":"RECRUITING","sponsor":"University of California, Los Angeles","startDate":"2024-03-28","conditions":"Prostate Cancer Metastatic Disease","enrollment":70},{"nctId":"NCT06424860","phase":"PHASE1","title":"Fish Oil, Metformin and Heart Health in PCOS","status":"RECRUITING","sponsor":"University of Alberta","startDate":"2025-11-01","conditions":"PCOS, Cardiovascular Disease, Atherosclerotic Cardiovascular Disease","enrollment":146},{"nctId":"NCT05868954","phase":"NA","title":"Implementation of a Mediterranean Diet Program for Overweight or Obese Pregnant Women in a Low-resource Clinical Setting","status":"COMPLETED","sponsor":"Wake Forest University Health Sciences","startDate":"2023-08-31","conditions":"Gestational Weight Gain, Diet, Healthy","enrollment":41},{"nctId":"NCT03207711","phase":"NA","title":"Delish Study: Diabetes Education to Lower Insulin, Sugars, and Hunger","status":"COMPLETED","sponsor":"University of California, San Francisco","startDate":"2017-02-17","conditions":"Diabetes Mellitus, Type 2","enrollment":60},{"nctId":"NCT06736366","phase":"NA","title":"Study With Two Coenzyme Q10 Products","status":"COMPLETED","sponsor":"University of Primorska","startDate":"2024-12-05","conditions":"Coenzyme Q Deficiency","enrollment":25},{"nctId":"NCT07265440","phase":"NA","title":"Effect of New Specialized Technique Using Effleurage Massage on Striae Gravidarum","status":"COMPLETED","sponsor":"Kafrelsheikh University","startDate":"2024-10-09","conditions":"Striae Gravidarum","enrollment":42},{"nctId":"NCT07265089","phase":"NA","title":"Zinc Oxide-Ozonated Olive Oil vs Metapex in Primary Anterior Teeth","status":"NOT_YET_RECRUITING","sponsor":"Cairo University","startDate":"2025-12-01","conditions":"Carious Anterior Teeth","enrollment":52},{"nctId":"NCT06049680","phase":"PHASE4","title":"Safety Study of SMOFlipid to Evaluate the Risk of Developing EFAD and/or PNAC in Pediatric and Adult Patients","status":"RECRUITING","sponsor":"Fresenius Kabi","startDate":"2024-10-28","conditions":"Malnutrition, Child, Malnutrition, Essential Fatty Acid Deficiency (EFAD)","enrollment":100},{"nctId":"NCT07187739","phase":"NA","title":"Effect of Mediterranean Diet on Nutrition in Parkinson's Disease Patients With Bilateral Subthalamic Deep Brain Stimulation","status":"RECRUITING","sponsor":"Ankara University","startDate":"2025-09-25","conditions":"Parkinson Disease, Deep Brain Stimulation, Deep Brain Stimulation Surgery","enrollment":24},{"nctId":"NCT07038252","phase":"NA","title":"The Effect of Oral SPM Supplementation on INflammation-induced Vascular Ageing in Obese Hypertensive Patients","status":"RECRUITING","sponsor":"Assistance Publique - Hôpitaux de Paris","startDate":"2025-11-26","conditions":"Hypertension, Obesity","enrollment":50},{"nctId":"NCT07111208","phase":"NA","title":"Ambient Air and Noise Effect on Cardiovascular Health Risk and Lifestyle Intervention to Attenuate It (METSGREEN)","status":"RECRUITING","sponsor":"Regina Grazuleviciene","startDate":"2025-10-24","conditions":"Cardiovascular Diseases (CVD), Metabolic Syndrome, Air Pollution Exposure","enrollment":180},{"nctId":"NCT07250659","phase":"NA","title":"Comparing Intermittent Fasting and Mediterranean Diet for Obesity","status":"COMPLETED","sponsor":"Kamil Dağcılar","startDate":"2022-09-01","conditions":"Weight Loss","enrollment":120},{"nctId":"NCT07055620","phase":"NA","title":"Effects of Different Dietary Models on Eating Behavior and Obesity Management in Overweight and Obese Individuals","status":"COMPLETED","sponsor":"Selcuk University","startDate":"2025-04-18","conditions":"Mediterranean Diet, Intermittent Fasting, Diet","enrollment":75},{"nctId":"NCT07199218","phase":"PHASE2","title":"Placebo-Controlled Study of Terpenes-Enriched Cannabis Oil T1/C28 for Children With Autism","status":"RECRUITING","sponsor":"Bazelet Nehushtan LtD.","startDate":"2025-10-05","conditions":"Autism, Autism Spectrum Disorder","enrollment":78},{"nctId":"NCT06342830","phase":"PHASE2","title":"Comparing the Effect of Different Intracanal Dressing on Failed Root Canal Treated Cases on Periapical Healing","status":"COMPLETED","sponsor":"Ain Shams University","startDate":"2024-06-20","conditions":"Periapical Disease","enrollment":60},{"nctId":"NCT06519097","phase":"PHASE2","title":"Study of IPMN Progression Prevention With Tocotrienol (SIPP-T3)","status":"ACTIVE_NOT_RECRUITING","sponsor":"H. Lee Moffitt Cancer Center and Research Institute","startDate":"2024-07-09","conditions":"Neoplasm of Pancreas, IPMN, Pancreatic","enrollment":4},{"nctId":"NCT06935097","phase":"NA","title":"Mediterranean Diet Intervention Among Men at LBJ Hospital With Prostate Cancer","status":"ENROLLING_BY_INVITATION","sponsor":"M.D. Anderson Cancer Center","startDate":"2025-10-24","conditions":"Prostate Cancer","enrollment":25},{"nctId":"NCT05396846","phase":"NA","title":"My Best GI Eating Study","status":"ACTIVE_NOT_RECRUITING","sponsor":"University of Michigan","startDate":"2023-06-13","conditions":"Colorectal Neoplasms","enrollment":240},{"nctId":"NCT07218328","phase":"NA","title":"Food is Medicine in Survivorship: Examining the Feasibility and Impact of a Scalable Food Delivery and Culinary Medicine Program (FoodiiS) Among Pediatric Cancer Survivors and Their Families","status":"NOT_YET_RECRUITING","sponsor":"M.D. Anderson Cancer Center","startDate":"2026-04-30","conditions":"Pediatric Cancer","enrollment":21},{"nctId":"NCT06992115","phase":"NA","title":"A Study of the MIND Diet for Persons With Multiple Sclerosis","status":"RECRUITING","sponsor":"Icahn School of Medicine at Mount Sinai","startDate":"2025-05-12","conditions":"Multiple Sclerosis","enrollment":100},{"nctId":"NCT04816994","phase":"PHASE3","title":"Effect of Cannabis Extract on Acute Radicular Pain and on Analgesic Requirement","status":"RECRUITING","sponsor":"Hadassah Medical Organization","startDate":"2018-01-07","conditions":"Acute Radicular Back Pain, Cannabis","enrollment":200},{"nctId":"NCT07200934","phase":"NA","title":"Effect of Adding TENS to Mediterranean Diet on Appetite and Liver Enzymes in Nonalcoholic Fatty Liver Patients","status":"NOT_YET_RECRUITING","sponsor":"Cairo University","startDate":"2025-09-30","conditions":"Nonalcoholic Fatty Liver","enrollment":50},{"nctId":"NCT01624792","phase":"NA","title":"Eicosapentaenoic Acid and Protein Modulation to Induce Anabolism in Chronic Obstructive Pulmonary Disease (COPD): Aim 2","status":"COMPLETED","sponsor":"Texas A&M University","startDate":"2011-10-25","conditions":"Chronic Obstructive Pulmonary Disease, Muscle Wasting","enrollment":64},{"nctId":"NCT06570889","phase":"PHASE3","title":"VItamin D in pregnanCy for prevenTion Of eaRlY Childhood Asthma","status":"RECRUITING","sponsor":"Professor Klaus Bønnelykke","startDate":"2024-12-20","conditions":"Asthma, Respiratory Tract Infections, Gastrointestinal Infection","enrollment":2000},{"nctId":"NCT01871350","phase":"NA","title":"Nutrition Intervention During Chemotherapy","status":"COMPLETED","sponsor":"Texas A&M University","startDate":"2013-04-26","conditions":"Cancer Patients Receiving Chemotherapy or Chemoradiotherapy","enrollment":31},{"nctId":"NCT07197073","phase":"NA","title":"Antibacterial Effect of Ozonated Olive Oil, Propolis and Chlorhexidine Mouthwashes in Pediatric Patients","status":"COMPLETED","sponsor":"Alexandria University","startDate":"2025-02-25","conditions":"Oral Hygiene, Oral Health","enrollment":51},{"nctId":"NCT03869957","phase":"NA","title":"Effect of Parenteral Nutrition With n-3 PUFAs on Patients With Intestinal Failure","status":"COMPLETED","sponsor":"Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran","startDate":"2019-12-01","conditions":"Intestinal Failure","enrollment":20},{"nctId":"NCT07189637","phase":"NA","title":"The Combined Effect of the Mediterranean Diet and Intermittent Fasting on Hypertension","status":"NOT_YET_RECRUITING","sponsor":"Nadide Gizem Tarakci Filiz","startDate":"2025-11-01","conditions":"Hypertension","enrollment":48},{"nctId":"NCT05585476","phase":"NA","title":"A Laser and Topical Treatment Combination in the Vulvo-vaginal Atrophy Management in Breast Cancer Patients.","status":"NOT_YET_RECRUITING","sponsor":"Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz","startDate":"2025-10","conditions":"Female Urogenital Diseases, Breast Cancer Female","enrollment":180},{"nctId":"NCT07182292","phase":"NA","title":"Effect of a Combined Exercise and Anti-Inflammatory Nutritional Intervention in Frail Older Adults","status":"NOT_YET_RECRUITING","sponsor":"Fundacion Miguel Servet","startDate":"2025-10-01","conditions":"Frail Elderly Syndrome, Malnutrition Elderly","enrollment":158},{"nctId":"NCT05784506","phase":"NA","title":"Metabolites Profiling Reveals Nutrient Processing Patterns Upon Dietary Loading","status":"COMPLETED","sponsor":"Nanjing Medical University","startDate":"2023-09-01","conditions":"Metabolism Disorder, Nutrition","enrollment":147},{"nctId":"NCT06192407","phase":"NA","title":"Fatty Acid Modulation of Brain Function in Older Adults","status":"RECRUITING","sponsor":"University of Vermont","startDate":"2024-04-15","conditions":"Aging","enrollment":60},{"nctId":"NCT07178067","phase":"","title":"Longitudinal Evaluation of Short-Chain Fatty Acid Profiles During the Natural Disease Course and a Mediterranean Diet Intervention in Amyotrophic Lateral Sclerosis Patients","status":"COMPLETED","sponsor":"George Emil Palade University of Medicine, Pharmacy, Sciences and Technology of Targu Mures","startDate":"2022-07-21","conditions":"Amyotrophic Lateral Sclerosis","enrollment":44},{"nctId":"NCT05007483","phase":"NA","title":"Efficacy of Diet on Quality of Life in Multiple Sclerosis","status":"ACTIVE_NOT_RECRUITING","sponsor":"Terry L. Wahls","startDate":"2022-02-10","conditions":"Multiple Sclerosis, Relapsing-Remitting","enrollment":162},{"nctId":"NCT05312424","phase":"PHASE1, PHASE2","title":"Annatto-derived GG for Statin-associated Myopathy","status":"RECRUITING","sponsor":"Texas Tech University Health Sciences Center","startDate":"2022-07-15","conditions":"Myopathy; Primary","enrollment":95},{"nctId":"NCT07170384","phase":"NA","title":"Mediterranean Diet and Disease Activity in Axial Spondyloarthritis Receiving Biologic Therapy","status":"NOT_YET_RECRUITING","sponsor":"Sinem Kübra Beke","startDate":"2025-09-08","conditions":"Axial Spondyloarthritis (Ankylosing Spondylitis)","enrollment":110},{"nctId":"NCT06737484","phase":"NA","title":"Effect of Topically Applied Olive Oil on Pruritus in Hemodialysis Patients: Pretest-posttest Model With Control Group","status":"COMPLETED","sponsor":"Inonu University","startDate":"2025-01-27","conditions":"Hemodialysis Patients, Pruritus","enrollment":68},{"nctId":"NCT06883292","phase":"NA","title":"The Effects of Tyrosol and Creatine on Endurance, Strength, and Fatigue Resistance in Healthy Adults","status":"COMPLETED","sponsor":"Applied Science & Performance Institute","startDate":"2025-03-24","conditions":"Tyrosol, Creatine, Endurance Performance","enrollment":50},{"nctId":"NCT06971445","phase":"NA","title":"Effect of Omega-3 Supplementation on Pregnant Outcomes and Inflammation Markers of Women Infected With HIV Using Antiretroviral Therapy","status":"ENROLLING_BY_INVITATION","sponsor":"Instituto Nacional de Perinatologia Isidro Espinosa de los Reyes","startDate":"2025-05-14","conditions":"Pregnant HIV Positive Women","enrollment":92},{"nctId":"NCT07164014","phase":"NA","title":"The Impact of the Mediterranean Diet on Anthropometric Indices, Lipid Profiles, Energy Metabolism Signaling Proteins and Inflammatory Cytokines in Psychiatric Patients With Metabolic Syndrome","status":"COMPLETED","sponsor":"King Saud University","startDate":"2024-05-01","conditions":"Metabolic Syndrome (MetS), Psychiatric Disorders, Mediterranean Diet","enrollment":144},{"nctId":"NCT07100587","phase":"NA","title":"Ketogenic vs. Mediterranean Diet on Metabolic and Hormonal Parameters in Patients With Active Acromegaly","status":"COMPLETED","sponsor":"University of Palermo","startDate":"2024-06-30","conditions":"Acromegaly","enrollment":26},{"nctId":"NCT07156097","phase":"NA","title":"Effects of Boron and Mediterranean Diets on Gut Microbiota and Metabolic Health","status":"COMPLETED","sponsor":"Dicle University","startDate":"2023-01-05","conditions":"Obesity, Dietary Intervention, Gut Microbiota","enrollment":40},{"nctId":"NCT07030543","phase":"NA","title":"Feasibility Of Individualized Dietary Plan (Idp) On Glycemic Control And Total Cholestrol In Diabetic Patients At Diabetes Hospital And Research Centre Peshawar","status":"COMPLETED","sponsor":"Khyber Medical University Peshawar","startDate":"2025-02-01","conditions":"Type 2 Diabetes Mellitus","enrollment":122},{"nctId":"NCT07144488","phase":"NA","title":"The Impact of Olive Oil Polyphenol Supplementation on Metabolic Syndrome Parameters: Preclinical Investigations Have Demonstrated That Olive Oil Polyphenols, Notably Oleocanthal, Oleacein, and Allied Secoiridoids, Possess Anti-inflammatory and Antioxidant Attributes","status":"COMPLETED","sponsor":"Apostolos Loukas Medical Centre Cyprus","startDate":"2024-09-01","conditions":"Metabolic Syndrome","enrollment":106},{"nctId":"NCT06374199","phase":"NA","title":"Med-South Lifestyle Program for Pregnancy","status":"COMPLETED","sponsor":"University of North Carolina, Chapel Hill","startDate":"2024-05-10","conditions":"Pregnancy Complications","enrollment":35},{"nctId":"NCT07134140","phase":"NA","title":"Omega-3 Fatty Acids in Muscle Function and Health","status":"NOT_YET_RECRUITING","sponsor":"European University Cyprus","startDate":"2025-09","conditions":"Healthy","enrollment":32}],"_emaApprovals":[],"_faersSignals":[{"count":57,"reaction":"FATIGUE"},{"count":56,"reaction":"NAUSEA"},{"count":54,"reaction":"VOMITING"},{"count":34,"reaction":"BACK PAIN"},{"count":33,"reaction":"PLEURAL EFFUSION"},{"count":33,"reaction":"SEPSIS"},{"count":32,"reaction":"C-REACTIVE PROTEIN INCREASED"},{"count":32,"reaction":"DIARRHOEA"},{"count":31,"reaction":"BRAIN OEDEMA"},{"count":31,"reaction":"VASCULAR DEVICE INFECTION"}],"administration":{"route":"Topical"},"crossReferences":{"chemblId":"CHEMBL2107910"},"_approvalHistory":[],"publicationCount":14529,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"approved","brandName":"OLIVE OIL","genericName":"OLIVE OIL","companyName":"","companyId":"","modality":"","firstApprovalDate":"2013","aiSummary":"","enrichmentLevel":3,"visitCount":0,"regulatoryByCountry":[{"country_code":"US","regulator":"FDA","status":"approved","approval_date":"2016-07-20T00:00:00.000Z","mah":"BAXTER HLTHCARE CORP","brand_name_local":null,"application_number":"NDA204508"},{"country_code":"CA","regulator":"Health Canada","status":"approved","approval_date":null,"mah":"","brand_name_local":"","application_number":""},{"country_code":"IL","regulator":"MOH","status":"likely_approved","approval_date":null,"mah":null,"brand_name_local":null,"application_number":null},{"country_code":"SG","regulator":"HSA","status":"likely_approved","approval_date":null,"mah":null,"brand_name_local":null,"application_number":null},{"country_code":"AE","regulator":"MOH","status":"likely_approved","approval_date":null,"mah":null,"brand_name_local":null,"application_number":null},{"country_code":"KR","regulator":"MFDS","status":"likely_approved","approval_date":null,"mah":null,"brand_name_local":null,"application_number":null},{"country_code":"AU","regulator":"TGA","status":"likely_approved","approval_date":null,"mah":null,"brand_name_local":null,"application_number":null},{"country_code":"GB","regulator":"MHRA","status":"likely_approved","approval_date":null,"mah":null,"brand_name_local":null,"application_number":null}],"trialStats":{"total":0,"withResults":0},"validation":{"fieldsValidated":1,"lastValidatedAt":"2026-04-20T03:12:02.240154+00:00","fieldsConflicting":0,"overallConfidence":0.95},"verificationStatus":"partial","dataCompleteness":{"mechanism":false,"indications":true,"safety":false,"trials":true,"score":2}}