{"id":"oleandrin","rwe":[],"tags":[{"label":"oleandrin","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"}],"phase":"phase_1","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"corrigen","offLabel":[],"synonyms":["oleandrin","corrigen","foliandrin","folinerin","neriostene","oleandrine"],"timeline":[],"aiSummary":"Corrigen is a small molecule modality. It is also known by the synonyms ANVIRZEL, NSC-692219, OLEANDRIN, and OLEANDRIN.","approvals":[],"brandName":"Corrigen","ecosystem":[],"mechanism":{"target":"Neurogenic locus notch homolog protein 1","modality":"Small Molecule","drugClass":"oleandrin","explanation":"Imagine Corrigen as a key that unlocks a specific process in the body, allowing it to function properly. This process is crucial for maintaining health, but when it's disrupted, it can lead to disease. By restoring balance to this process, Corrigen may help alleviate symptoms and improve overall well-being.","oneSentence":"Corrigen works by interacting with cellular targets to produce its therapeutic effects.","technicalDetail":"Corrigen's exact mechanism of action is not well-documented, but it is believed to involve the inhibition of certain cellular pathways, potentially through the binding of oleandrin to specific protein targets."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/3399","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=OLEANDRIN","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T15:09:59.225601","biosimilars":[],"competitors":[],"dataSources":[{"url":"https://drugcentral.org","name":"DrugCentral","fields":["indications","contraindications","safety","target","drugInteractions"],"retrievedDate":"2026-04-07"}],"genericName":"oleandrin","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"administration":{},"crossReferences":{"UNII":"II95UDU7I4","CHEBI":"CHEBI:59030","UMLSCUI":"C0069397","ChEMBL_ID":"CHEMBL4285883","DRUGBANK_ID":"DB12843","PUBCHEM_CID":"11541511","SNOMEDCT_US":"35871001","IUPHAR_LIGAND_ID":"12618","MESH_SUPPLEMENTAL_RECORD_UI":"C021065"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":208,"therapeuticAreas":["Neuroscience"],"biosimilarFilings":[],"recentPublications":[],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}