{"id":"olanzapine-10-milligram","safety":{"commonSideEffects":[{"rate":"30-40","effect":"Weight gain"},{"rate":"20-30","effect":"Sedation"},{"rate":"15-25","effect":"Metabolic syndrome / hyperglycemia"},{"rate":"15-20","effect":"Hyperlipidemia"},{"rate":"5-10","effect":"Akathisia"},{"rate":"5-10","effect":"Extrapyramidal symptoms"},{"rate":"5-10","effect":"Orthostatic hypotension"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Olanzapine is an atypical antipsychotic that antagonizes dopamine D2 receptors and serotonin 5-HT2A receptors, which are implicated in psychosis and mood dysregulation. By blocking these receptors, it reduces positive symptoms of schizophrenia (hallucinations, delusions) and negative symptoms, and is also effective in bipolar disorder for acute mania and maintenance treatment.","oneSentence":"Olanzapine blocks dopamine and serotonin receptors in the brain to reduce psychotic symptoms and stabilize mood.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T01:24:02.164Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Schizophrenia"},{"name":"Bipolar I disorder (acute mania and maintenance)"},{"name":"Treatment-resistant depression (adjunctive)"}]},"trialDetails":[],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"Olanzapine 10 milligram","genericName":"Olanzapine 10 milligram","companyName":"Mercy Bon Secours Saint Vincent Medical Center","companyId":"mercy-bon-secours-saint-vincent-medical-center","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Olanzapine blocks dopamine and serotonin receptors in the brain to reduce psychotic symptoms and stabilize mood. Used for Schizophrenia, Bipolar I disorder (acute mania and maintenance), Treatment-resistant depression (adjunctive).","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":1,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":false,"score":3}}