{"id":"od-phoenix","rwe":[],"tags":[],"phase":"discontinued","safety":{"boxedWarnings":[],"drugInteractions":[],"commonSideEffects":[],"contraindications":[],"specialPopulations":{"Pregnancy":"Data not available","Geriatric use":"Data not available","Paediatric use":"Data not available","Renal impairment":"Data not available","Hepatic impairment":"Data not available"},"seriousAdverseEvents":[]},"status":"discontinued","trials":["NCT02430558","NCT02736318"],"aliases":["Osteochondral allograft"],"patents":[],"pricing":[],"offLabel":[],"timeline":[{"date":"","type":"negative","milestone":"OD-PHOENIX discontinued","regulator":"none","description":"Development program terminated; drug did not advance to regulatory approval or commercial launch."},{"date":"","type":"neutral","milestone":"2 clinical trials registered","regulator":"none","description":"Two clinical trials initiated but specific phases, indications, and outcomes not publicly available."}],"aiSummary":"OD-PHOENIX is a discontinued therapeutic candidate developed by TBF Genie Tissulaire. The drug entered clinical development with a total of 2 registered trials but did not advance to regulatory approval. No FDA label, EMA marketing authorization, or published clinical data are available in public databases. The discontinuation suggests either insufficient efficacy/safety signals, commercial viability concerns, or strategic portfolio decisions by the originating company. Without access to mechanism of action, indication focus, or clinical trial results, institutional assessment of this asset is severely limited. This profile reflects the scarcity of publicly available information on this withdrawn program.","brandName":"OD-PHOENIX","companyId":"tbf-genie-tissulaire","ecosystem":[],"mechanism":{"target":"Data not available","novelty":"Data not available","modality":"other","drugClass":"Data not available","explanation":"No mechanism of action data is available for OD-PHOENIX. The drug was discontinued before reaching regulatory approval or substantial public disclosure of its pharmacological properties. Without access to preclinical studies, IND applications, or clinical trial protocols, the molecular target, pathway modulation, and pharmacodynamic profile cannot be determined.","oneSentence":"Data not available","technicalDetail":"Data not available"},"commercial":{"notes":"OD-PHOENIX was discontinued and never commercialized. No revenue data available.","yoyGrowth":"","launchDate":"","marketShare":"","revenueYear":"","annualCostUS":"","currentRevenue":"","percentOfCompany":"","patientPopulation":"","peakSalesEstimate":"","genericCompetition":"no"},"references":[],"biosimilars":[],"companyName":"TBF Genie Tissulaire","competitors":[],"genericName":"OD-PHOENIX","indications":{"approved":[],"offLabel":[],"pipeline":[{"name":"Data not available","notes":"2 clinical trials registered but indication(s) not publicly disclosed","phase":"Data not available","status":"Data not available"}]},"labelChanges":[],"relatedDrugs":[],"trialDetails":[{"nctId":"NCT02430558","phase":"PHASE1, PHASE2","title":"Second Line Treatment of Knee Osteochondral Lesion With Treated Osteochondral Graft","status":"TERMINATED","sponsor":"TBF Genie Tissulaire","startDate":"2016-04-05","conditions":"Cartilage Injury","enrollment":10},{"nctId":"NCT02736318","phase":"PHASE1, PHASE2","title":"OD-PHOENIX in Talus Osteochondral Lesion","status":"TERMINATED","sponsor":"TBF Genie Tissulaire","startDate":"2017-01-27","conditions":"Talus Osteochondral Defect","enrollment":12}],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"administration":{"icon":"❓","route":"Data not available","frequency":"Data not available","formulation":"Data not available"},"formularyStatus":[],"apiManufacturers":[],"developmentCodes":[],"ownershipHistory":[{"notes":"Company ownership and development timeline not publicly documented","period":"Data not available–present","companyName":"TBF Genie Tissulaire","relationship":"Originator"}],"therapeuticAreas":["Other"],"trialPhaseCounts":{"PHASE1, PHASE2":2},"biosimilarFilings":[],"firstApprovalDate":"","companionDiagnostics":[],"firstApprovalCountry":null,"genericManufacturerList":[],"modality":"Biologic","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":2,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":true,"score":2}}