{"id":"octabenzone","rwe":[{"pmid":"40263761","year":"2025","title":"Quantifying the Effect of Dietary Microplastics on the Potential for Biological Uptake of Environmental Contaminants and Polymer Additives.","finding":"","journal":"Environmental science & technology","studyType":"Clinical Study"},{"pmid":"39877881","year":"2024","title":"Comparative evaluation of trimethylated α-, β-, and γ-cyclodextrins as optimal dispersants for ready biodegradability testing of poorly water-soluble substances.","finding":"","journal":"Journal of pesticide science","studyType":"Clinical Study"},{"pmid":"31121201","year":"2019","title":"Predicting estrogen receptor activation by a group of substituted phenols: An integrated approach to testing and assessment case study.","finding":"","journal":"Regulatory toxicology and pharmacology : RTP","studyType":"Clinical Study"},{"pmid":"28560359","year":"2017","title":"Analysis of plastic residues in maple sap and syrup collected from tubing systems sanitized with isopropyl alcohol.","finding":"","journal":"Heliyon","studyType":"Clinical Study"},{"pmid":"25739276","year":"2014","title":"[Determination of ultraviolet filters in environmental aqueous samples by dispersive liquid-liquid microextraction with online derivatization-gas chromatography-mass spectrometry].","finding":"","journal":"Se pu = Chinese journal of chromatography","studyType":"Clinical Study"}],"tags":[{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":["octabenzone"],"offLabel":[],"synonyms":["octabenzone"],"timeline":[],"approvals":[],"ecosystem":[],"mechanism":{"modality":"Small Molecule","explanation":"Imagine your body's cells as a complex network of roads and intersections. Small molecules like octabenzone are like special keys that can unlock specific intersections, allowing different cellular processes to communicate with each other. However, the exact roads and intersections that octabenzone interacts with are still unknown.","oneSentence":"Octabenzone is a small molecule that works by interacting with specific biological pathways, but the exact mechanism is unknown.","technicalDetail":"As a small molecule, octabenzone is likely to work through specific binding interactions with target proteins or receptors, potentially modulating downstream signaling pathways. However, the precise molecular mechanisms underlying its activity remain to be elucidated."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/3392","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=OCTABENZONE","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T13:03:42.024147","biosimilars":[],"competitors":[],"genericName":"octabenzone","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"UNII":"73P3618V2E","INN_ID":"2364","UMLSCUI":"C2698646","ChEMBL_ID":"CHEMBL1977129","KEGG_DRUG":"D00441","PUBCHEM_CID":"15797"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":6,"therapeuticAreas":["Other"],"biosimilarFilings":[],"recentPublications":[{"date":"2025 May 6","pmid":"40263761","title":"Quantifying the Effect of Dietary Microplastics on the Potential for Biological Uptake of Environmental Contaminants and Polymer Additives.","journal":"Environmental science & technology"},{"date":"2024 Nov 20","pmid":"39877881","title":"Comparative evaluation of trimethylated α-, β-, and γ-cyclodextrins as optimal dispersants for ready biodegradability testing of poorly water-soluble substances.","journal":"Journal of pesticide science"},{"date":"2019 Aug","pmid":"31121201","title":"Predicting estrogen receptor activation by a group of substituted phenols: An integrated approach to testing and assessment case study.","journal":"Regulatory toxicology and pharmacology : RTP"},{"date":"2017 May","pmid":"28560359","title":"Analysis of plastic residues in maple sap and syrup collected from tubing systems sanitized with isopropyl alcohol.","journal":"Heliyon"},{"date":"2014 Oct","pmid":"25739276","title":"[Determination of ultraviolet filters in environmental aqueous samples by dispersive liquid-liquid microextraction with online derivatization-gas chromatography-mass spectrometry].","journal":"Se pu = Chinese journal of chromatography"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","brandName":"OCTABENZONE","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Octabenzone is a small molecule with the synonyms BENZOPHENONE-12, NSC-163400, OCTABENZONA, OCTABENZONE, and OCTABENZONE.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}