{"id":"obturator-nerve-regional-block","safety":{"commonSideEffects":[{"rate":null,"effect":"Vascular puncture"},{"rate":null,"effect":"Nerve injury"},{"rate":null,"effect":"Local anesthetic toxicity"},{"rate":null,"effect":"Hematoma"}]},"_chembl":{"chemblId":"CHEMBL4297796","moleculeType":"Unknown"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"This is a regional anesthesia technique in which local anesthetic is injected near the obturator nerve, which innervates the adductor muscles of the thigh and provides sensory coverage to the medial knee. The block interrupts nerve conduction, producing anesthesia and analgesia in the distribution of the obturator nerve. It is commonly used as an adjunct to other regional blocks or general anesthesia during orthopedic and urological procedures.","oneSentence":"An obturator nerve regional block is a local anesthetic procedure that temporarily numbs the obturator nerve to provide pain relief and muscle relaxation in the inner thigh and hip region.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-27T23:57:58.452Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Anesthesia and analgesia for knee surgery"},{"name":"Anesthesia and analgesia for hip surgery"},{"name":"Anesthesia and analgesia for transurethral resection of bladder tumors"}]},"trialDetails":[{"nctId":"NCT07477730","phase":"NA","title":"Local Infiltration Analgesia Versus Quadruple Nerve Blocks in Total Knee Arthroplasty.","status":"NOT_YET_RECRUITING","sponsor":"CMC Ambroise Paré","startDate":"2026-06-01","conditions":"Total Knee Arthroplasty","enrollment":80},{"nctId":"NCT06920186","phase":"NA","title":"Infiltration or Nerve Blocks in Addition to Adductor Canal Block","status":"NOT_YET_RECRUITING","sponsor":"GCS Ramsay Santé pour l'Enseignement et la Recherche","startDate":"2026-01-14","conditions":"Gonarthrosis, Total Knee Arthroplasty","enrollment":100},{"nctId":"NCT07263932","phase":"","title":"PENG vs PHPB for Hip Arthroplasty Analgesia","status":"RECRUITING","sponsor":"Ankara City Hospital Bilkent","startDate":"2025-12-01","conditions":"PENG Block, Hip Arthroplasty, Total, QoR-15","enrollment":132},{"nctId":"NCT07239817","phase":"NA","title":"PENG Block + LIA For Endoprosthesis Surgery With Anterior Approach","status":"RECRUITING","sponsor":"ASST Gaetano Pini-CTO","startDate":"2025-12-01","conditions":"Hip Fractures, Arthroplasty, Replacement, Hip, Pain, Postoperative","enrollment":100},{"nctId":"NCT06257160","phase":"NA","title":"Superiority Randomized Controlled Trial of Ultrasound-guided PENG Block Compared to Surgical Infiltration in the Analgesia of Posterior Total Hip Arthroplasty Surgery","status":"COMPLETED","sponsor":"CHU de Reims","startDate":"2024-05-22","conditions":"Hip Arthropathy, Hip Arthrosis","enrollment":224},{"nctId":"NCT07153575","phase":"NA","title":"Postoperative Analgesia in Hip Arthroplasty","status":"ACTIVE_NOT_RECRUITING","sponsor":"Balikesir University","startDate":"2023-12-01","conditions":"Hip Fractures, Post Operative Pain, Postoperative Nausea and Vomiting","enrollment":60},{"nctId":"NCT07061223","phase":"NA","title":"SFIB vs PENG Block in the Anesthesia for Total Hip Replacement","status":"ENROLLING_BY_INVITATION","sponsor":"State Budgetary Healthcare Institution, National Medical Surgical Center N.A. N.I. Pirogov, Ministry of Health of Russia","startDate":"2025-07-01","conditions":"Regional Anesthesia, Hip Arthroplasty","enrollment":120},{"nctId":"NCT06989047","phase":"NA","title":"Ultrasound-Guided PENG Block vs Femoral Nerve Block for Analgesia Before Spinal Anesthesia in Hip Fracture Surgery","status":"NOT_YET_RECRUITING","sponsor":"Ain Shams University","startDate":"2025-05-30","conditions":"Proximal Femur Fracture, Hip Fracture, Pain Management","enrollment":60},{"nctId":"NCT06155903","phase":"NA","title":"Peripheral Nerve Blocks vs Selective Spinal Anesthesia in Patients With Femur Fracture","status":"COMPLETED","sponsor":"Federico II University","startDate":"2023-12-31","conditions":"Femur Fracture, Peripheral Nerve Block, Spinal Anesthesia","enrollment":78},{"nctId":"NCT06888349","phase":"NA","title":"The Effect of Combined IPACK Block with ACB Versus ACB Alone on Pain Management and Early Mobility After Total Knee Arthroplasty","status":"COMPLETED","sponsor":"Ain Shams University","startDate":"2023-01-23","conditions":"Postoperative Pain, Motor Activity","enrollment":50},{"nctId":"NCT05710107","phase":"NA","title":"QL vs PENG for Analgesia After Hip Arthroplasty","status":"COMPLETED","sponsor":"Medical University of South Carolina","startDate":"2023-02-07","conditions":"Block, Hip Replacement, Postoperative Pain","enrollment":106},{"nctId":"NCT05062356","phase":"PHASE1","title":"Pain Control Following Total Hip Arthroplasty","status":"COMPLETED","sponsor":"St. Mary's Research Center, Canada","startDate":"2021-11-04","conditions":"Chronic Postoperative Pain","enrollment":240},{"nctId":"NCT06229054","phase":"EARLY_PHASE1","title":"Dexmedetomidine in Obturator Nerve Block as an Analgesic in Transurethral Surgeries","status":"COMPLETED","sponsor":"Cairo University","startDate":"2024-02-01","conditions":"Dexmedetomidine","enrollment":56},{"nctId":"NCT05540847","phase":"NA","title":"Comparison of Interfascial Injection Versus Subpectineal Injection on Ultrasound-guided Obturator Nerve Block","status":"COMPLETED","sponsor":"Diskapi Teaching and Research Hospital","startDate":"2022-09-16","conditions":"Bladder Neoplasm","enrollment":60},{"nctId":"NCT05390450","phase":"NA","title":"Ultrasound-Guided Popliteal Plexus Block Versus Fascia Iliaca Block After Total Knee Arthroplasty","status":"COMPLETED","sponsor":"Tanta University","startDate":"2022-06-01","conditions":"Total Knee Arthroplasty, Popliteal Plexus Block, Fascia Iliaca Block","enrollment":60},{"nctId":"NCT05282849","phase":"NA","title":"Ultrasound Quadratus Lumborum Block Vs Fascia Iliaca Block in Pediatrics Undergoing Hip Surgery .","status":"UNKNOWN","sponsor":"Cairo University","startDate":"2022-04-04","conditions":"Developmental Dysplasia of the Hip","enrollment":30},{"nctId":"NCT04638569","phase":"NA","title":"Comparison of Obturator Nerve Block With Ultrasound Guidance and Anatomical Signs","status":"UNKNOWN","sponsor":"Muğla Sıtkı Koçman University","startDate":"2021-02-16","conditions":"Succesful Obturator Nerve Block, Bladder Tumor, Bleeding","enrollment":116},{"nctId":"NCT04499716","phase":"NA","title":"Quadriblock Versus \"IPACK + Femoral Triangle Block + Obturator Nerve Block\" in Total Knee Arthroplasty","status":"COMPLETED","sponsor":"Clinique Medipole Garonne","startDate":"2020-12-08","conditions":"Primary Total Knee Arthroplasty","enrollment":90},{"nctId":"NCT02406300","phase":"NA","title":"Anesthesia And Post-operative Mortality After Proximal Femur Fractures","status":"TERMINATED","sponsor":"Centro Hospitalar do Porto","startDate":"2015-04-01","conditions":"Hip Fractures","enrollment":57},{"nctId":"NCT04085640","phase":"NA","title":"Obturator Nerve Block in Total Hip Arthrosplasty","status":"COMPLETED","sponsor":"Clinique Medipole Garonne","startDate":"2020-01-14","conditions":"Primary Total Hip Arthroplasty","enrollment":60},{"nctId":"NCT03326999","phase":"PHASE4","title":"Does Adding an Additional Numbing Medication Injection in the Thigh Help With Pain Control After Knee Replacement Surgery?","status":"COMPLETED","sponsor":"Icahn School of Medicine at Mount Sinai","startDate":"2017-12-11","conditions":"Knee Osteoarthritis, Knee Rheumatism","enrollment":60},{"nctId":"NCT01547637","phase":"NA","title":"Preventing the Obturator Nerve Reflex","status":"COMPLETED","sponsor":"Milton S. Hershey Medical Center","startDate":"2012-05","conditions":"Bladder Injury","enrollment":40},{"nctId":"NCT01693900","phase":"NA","title":"Efficacy of Fascia Iliaca Block Versus Intraoperative Nerve Infiltration During Anterior Hip Replacement Surgery","status":"COMPLETED","sponsor":"Randy Fayne, DO","startDate":"2012-08","conditions":"Pain, Postoperative","enrollment":50},{"nctId":"NCT02696733","phase":"PHASE4","title":"Ultrasound-Guided ONB for Transurethral Procedures - Interadductor Approach","status":"UNKNOWN","sponsor":"Medical University of Warsaw","startDate":"2016-02","conditions":"Urinary Bladder Neoplasms, Transurethral Resection, Nerve Block","enrollment":100},{"nctId":"NCT02452944","phase":"NA","title":"Comparison of Nerve Stimulating Approach and Interfascial Injection Approach During Sono-guided Obturator Nerve Block","status":"COMPLETED","sponsor":"Gachon University Gil Medical Center","startDate":"2014-12","conditions":"Bladder Cancer","enrollment":62},{"nctId":"NCT02374008","phase":"PHASE4","title":"The Analgesic Effect of Combined Nerve Block and Systemic High Dose Glucocorticoid After Total Knee Arthroplasty.","status":"COMPLETED","sponsor":"Regionshospitalet Silkeborg","startDate":"2015-03","conditions":"Peripheral Nerve Block, Pain","enrollment":74},{"nctId":"NCT02408419","phase":"PHASE4","title":"Obturator Nerve Block in Patients With Hip Fracture","status":"WITHDRAWN","sponsor":"University of Aarhus","startDate":"2015-03","conditions":"Hip Fractures","enrollment":""},{"nctId":"NCT01868282","phase":"PHASE2, PHASE3","title":"Study of Pain Management Techniques Following Anterior Cruciate Ligament Repair Surgery","status":"COMPLETED","sponsor":"London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's","startDate":"2013-06","conditions":"Anterior Cruciate Ligament Reconstruction","enrollment":105},{"nctId":"NCT02067078","phase":"PHASE4","title":"Protracted Effect of Combined Nerve Blocks After Total Knee Arthroplasty","status":"COMPLETED","sponsor":"Regionshospitalet Silkeborg","startDate":"2014-02","conditions":"Total Knee Arthroplasty, Pain, Nerve Blocks","enrollment":75},{"nctId":"NCT02346357","phase":"NA","title":"Ultrasound-Guided Obturator Nerve Block for Ambulatory Hip Arthroscopy","status":"UNKNOWN","sponsor":"Benaroya Research Institute","startDate":"2014-05","conditions":"Pain","enrollment":70},{"nctId":"NCT01875289","phase":"NA","title":"Efficacy of a Modified Obturator Nerve Block Technique","status":"COMPLETED","sponsor":"Medical University of Graz","startDate":"2013-07","conditions":"Hip Surgery, Knee Surgery","enrollment":36},{"nctId":"NCT01511211","phase":"PHASE4","title":"Duration of Leg Nerve Blocks With Dexamethasone Added to Local Anesthetic","status":"WITHDRAWN","sponsor":"University of New Mexico","startDate":"2012-09","conditions":"Pain, Total Knee Arthroplasty","enrollment":""},{"nctId":"NCT01106001","phase":"PHASE4","title":"Study to Test the Efficacy of Periarticular Levo Bupivicaine Injection Following Primary Hip Arthroplasty","status":"COMPLETED","sponsor":"Orthopaedic Research and Innovation Foundation, Ireland","startDate":"2008-09","conditions":"Osteoarthritis","enrollment":91}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":6,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["bupivacaine"],"phase":"marketed","status":"active","brandName":"Obturator nerve regional block","genericName":"Obturator nerve regional block","companyName":"Icahn School of Medicine at Mount Sinai","companyId":"icahn-school-of-medicine-at-mount-sinai","modality":"Small molecule","firstApprovalDate":"","aiSummary":"An obturator nerve regional block is a local anesthetic procedure that temporarily numbs the obturator nerve to provide pain relief and muscle relaxation in the inner thigh and hip region. Used for Anesthesia and analgesia for knee surgery, Anesthesia and analgesia for hip surgery, Anesthesia and analgesia for transurethral resection of bladder tumors.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":1,"withResults":1},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}