{"id":"normal-nicotine-content-cigar","safety":{"commonSideEffects":[{"rate":null,"effect":"Nicotine dependence"},{"rate":null,"effect":"Respiratory irritation"},{"rate":null,"effect":"Cardiovascular effects"}]},"_chembl":{"chemblId":"CHEMBL3989563","moleculeType":"Small molecule","molecularWeight":"498.44"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"This product appears to be a standardized research tool used by Ohio State University Comprehensive Cancer Center, likely for comparative studies examining nicotine delivery, smoking patterns, or cancer risk assessment. It functions as a baseline or control product rather than a therapeutic agent with a defined pharmacological mechanism.","oneSentence":"A normal-nicotine content cigar serves as a research control or comparative product to study the effects of nicotine exposure and smoking behavior.","_ai_confidence":"low"},"_scrapedAt":"2026-03-27T23:57:40.822Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Research tool for studying nicotine exposure and smoking-related cancer risk"}]},"trialDetails":[{"nctId":"NCT06630728","phase":"PHASE4","title":"Addiction Potential of Very Low Nicotine Filtered Little Cigars","status":"RECRUITING","sponsor":"Ohio State University Comprehensive Cancer Center","startDate":"2025-02-13","conditions":"Smoking (Tobacco) Addiction","enrollment":50},{"nctId":"NCT02000921","phase":"NA","title":"Reduced Nicotine Content Cigarettes and Tobacco Switching Behaviors","status":"COMPLETED","sponsor":"University of Minnesota","startDate":"2013-12","conditions":"Tobacco Addiction, Dual Tobacco Use","enrollment":136}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":2,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["FLC"],"phase":"marketed","status":"active","brandName":"Normal nicotine content cigar","genericName":"Normal nicotine content cigar","companyName":"Ohio State University Comprehensive Cancer Center","companyId":"ohio-state-university-comprehensive-cancer-center","modality":"Small molecule","firstApprovalDate":"","aiSummary":"A normal-nicotine cigar product designed as a research or control comparator to study nicotine exposure and smoking-related health outcomes. Used for Research/control product for smoking and cancer studies.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}