{"id":"norgesterone","rwe":[],"tags":[{"label":"norgesterone","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"norvinodrel","offLabel":[],"synonyms":["norgesterone","norvinodrel","vinylestrenolone"],"timeline":[],"approvals":[],"brandName":"Norvinodrel","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"norgesterone","explanation":"Imagine your body has a delicate balance of hormones that control your menstrual cycle and pregnancy. Progesterone is one of these hormones that helps prepare the uterus for a fertilized egg. Norgesterone is a synthetic version of progesterone that helps maintain this balance by binding to the same receptors in the body, but its effects and safety are not well-understood.","oneSentence":"Norgesterone works by mimicking the effects of the hormone progesterone in the body.","technicalDetail":"Norgesterone exerts its effects by binding to progesterone receptors in the body, activating gene transcription and influencing various physiological processes, including uterine preparation, menstrual cycle regulation, and possibly other hormonal functions."},"_wikipedia":{"url":"https://en.wikipedia.org/wiki/Norgesterone","title":"Norgesterone","extract":"Norgesterone, also known as norvinodrel or vinylestrenolone and sold under the brand name Vestalin, is a progestin medication which was formerly used in birth control pills for women but is now no longer marketed. It was used in combination with the estrogen ethinylestradiol. It is taken by mouth.","wiki_history":"==History==\nNorgesterone was first described in 1962.","wiki_society_and_culture":"==Society and culture==\n\n===Generic names===\nNorgesterone is the generic name of the drug and its .\n\n===Brand names===\nNorgesterone was marketed in combination with ethinylestradiol, an estrogen, as a birth control pill under the brand name Vestalin."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/3204","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=NORGESTERONE","fields":["publications"],"source":"PubMed/NCBI"},{"id":3,"url":"https://en.wikipedia.org/wiki/Norgesterone","fields":["history","overview"],"source":"Wikipedia"}],"_enrichedAt":"2026-03-30T13:02:43.337228","biosimilars":[],"competitors":[],"genericName":"norgesterone","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"UNII":"YFS274763Y","CHEBI":"CHEBI:135271","INN_ID":"1715","UMLSCUI":"C0603673","ChEMBL_ID":"CHEMBL2106812","PUBCHEM_CID":"65606","MESH_SUPPLEMENTAL_RECORD_UI":"C008678"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":2,"therapeuticAreas":["Other"],"biosimilarFilings":[],"recentPublications":[],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Norvinodrel is a small molecule with synonyms including NORGESTERONA, NORGESTERONE, and NSC-72160.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}