{"id":"norethisterone-ethinylestradiol","safety":{"commonSideEffects":[{"rate":"10-20%","effect":"Nausea"},{"rate":"10-20%","effect":"Headache"},{"rate":"5-10%","effect":"Breast tenderness"},{"rate":"5-10%","effect":"Mood changes"}]},"_chembl":{"chemblId":"CHEMBL3187229","moleculeType":"Small molecule","molecularWeight":"410.60"},"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"Norethisterone and ethinylestradiol work together to prevent ovulation and thicken cervical mucus, preventing sperm from reaching the egg. This combination of hormones is used in birth control pills to prevent pregnancy.","oneSentence":"Norethisterone is a progestogen that acts as an agonist of the progesterone receptor, while ethinylestradiol is an estrogen that acts as an agonist of the estrogen receptor.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T01:23:19.732Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Contraception"}]},"trialDetails":[{"nctId":"NCT07074327","phase":"PHASE1","title":"Effects of VX-407 on the Pharmacokinetics of Oral Contraceptives in Healthy Participants","status":"ACTIVE_NOT_RECRUITING","sponsor":"Vertex Pharmaceuticals Incorporated","startDate":"2025-07-11","conditions":"Autosomal Dominant Polycystic Kidney Disease (ADPKD)","enrollment":74},{"nctId":"NCT07446400","phase":"PHASE1","title":"A Trial to Examine the Interaction of Repinatrabit With Ethinyl Estradiol/Norethindrone, Metformin,Carbamazepine, Rosuvastatin, and Methotrexate When Administered Together","status":"NOT_YET_RECRUITING","sponsor":"Otsuka Pharmaceutical Development & Commercialization, Inc.","startDate":"2026-03-20","conditions":"Healthy Volunteers","enrollment":48},{"nctId":"NCT03905941","phase":"EARLY_PHASE1","title":"Relative Desirability of Metformin vs. Birth Control Pill in Treating PCOS in Women of Later Reproductive Age","status":"WITHDRAWN","sponsor":"University of Virginia","startDate":"2021-08-23","conditions":"Polycystic Ovary Syndrome","enrollment":""},{"nctId":"NCT03106454","phase":"PHASE3","title":"Ovulation Incidence in Oral Contraceptive Users","status":"COMPLETED","sponsor":"University of Southern California","startDate":"2014-08","conditions":"Contraception, Ovulation","enrollment":58},{"nctId":"NCT07215806","phase":"PHASE1","title":"Effect of Evobrutinib on Pharmacokinetics of a Combined Oral Contraceptive","status":"COMPLETED","sponsor":"Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany","startDate":"2022-08-24","conditions":"Healthy","enrollment":20},{"nctId":"NCT06186271","phase":"","title":"International Active Surveillance Study: Safety of Estrogen Estetrol (E4) Contraceptive Study (INAS-SEECS)","status":"RECRUITING","sponsor":"Center for Epidemiology and Health Research, Germany","startDate":"2025-04-24","conditions":"Contraception","enrollment":68100},{"nctId":"NCT01246791","phase":"PHASE3","title":"Pharmacokinetics of NPC-01 After Single Oral Administration in Healthy Female Volunteers","status":"COMPLETED","sponsor":"Nobelpharma","startDate":"2010-11","conditions":"Healthy","enrollment":12},{"nctId":"NCT00902746","phase":"PHASE3","title":"Efficacy and Safety, Long-Term Study of NPC-01 to Treat Dysmenorrhea Associated With Endometriosis","status":"COMPLETED","sponsor":"Nobelpharma","startDate":"2009-05","conditions":"Dysmenorrhea","enrollment":149},{"nctId":"NCT02636972","phase":"","title":"The Progression From Dysmenorrhoea to Chronic Pelvic Pain","status":"COMPLETED","sponsor":"University of Adelaide","startDate":"2014-11","conditions":"Dysmenorrhoea, Pelvic Pain, Chronic Pain","enrollment":56},{"nctId":"NCT00746096","phase":"PHASE3","title":"Efficacy and Safety Study of Low Dose Oral Contraceptive Pill to Treat Primary Dysmenorrhea","status":"COMPLETED","sponsor":"Nobelpharma","startDate":"2008-09","conditions":"Dysmenorrhea","enrollment":115},{"nctId":"NCT01253824","phase":"PHASE3","title":"Pharmacodynamics of NPC-01/IKH-01; Effect of NPC-01/IKH-01 on Sexual Hormone Concentrations in Healthy Female Volunteers","status":"COMPLETED","sponsor":"Nobelpharma","startDate":"2011-01","conditions":"Healthy","enrollment":14},{"nctId":"NCT01129102","phase":"PHASE3","title":"Efficacy and Safety Study of NPC-01 to Treat Dysmenorrhea","status":"COMPLETED","sponsor":"Nobelpharma","startDate":"2010-05","conditions":"Dysmenorrhea","enrollment":215},{"nctId":"NCT06460948","phase":"EARLY_PHASE1","title":"Identifying Oxytocin Deficiency in Adults With Pituitary Disease","status":"RECRUITING","sponsor":"Elizabeth Austen Lawson","startDate":"2024-11-13","conditions":"Arginine Vasopressin Deficiency, Oxytocin Deficiency","enrollment":32},{"nctId":"NCT06310616","phase":"PHASE1","title":"A Study to Investigate the Potential Drug-Drug Interaction Between VH4524184 and Oral Contraceptive (Loestrin) in Healthy Adult Female Participants","status":"COMPLETED","sponsor":"ViiV Healthcare","startDate":"2024-03-06","conditions":"HIV Infections","enrollment":26},{"nctId":"NCT01656434","phase":"PHASE3","title":"Study of the Contraceptive Efficacy and Safety of a NOMAC-E2 Combined Oral Contraceptive (COC)(P06448)","status":"TERMINATED","sponsor":"Organon and Co","startDate":"2012-11-02","conditions":"Contraception","enrollment":3173},{"nctId":"NCT05891262","phase":"PHASE1","title":"A Study to Evaluate the Drug-drug Interaction of BMS-986196 With Oral Contraceptives in Healthy Female Participants","status":"COMPLETED","sponsor":"Bristol-Myers Squibb","startDate":"2023-06-06","conditions":"Healthy Female Volunteers","enrollment":15},{"nctId":"NCT05129878","phase":"NA","title":"Effect of EE/NETA With Scaling on Periodontium and hsCRP in PCOS Women With Gingivitis","status":"COMPLETED","sponsor":"Postgraduate Institute of Dental Sciences Rohtak","startDate":"2022-01-01","conditions":"Gingivitis, PCOS","enrollment":79},{"nctId":"NCT05579574","phase":"PHASE1","title":"A Study to Investigate the Interaction of BMS-986322 and a Combined Oral Hormonal Contraceptive (Ethinyl Estradiol [EE]/Norethindrone [NET]) in Healthy Female Participants","status":"COMPLETED","sponsor":"Bristol-Myers Squibb","startDate":"2022-10-21","conditions":"Healthy Participants","enrollment":42},{"nctId":"NCT04423068","phase":"EARLY_PHASE1","title":"Inpatient Adolescent Contraception","status":"COMPLETED","sponsor":"Children's Mercy Hospital Kansas City","startDate":"2020-12-10","conditions":"Pregnancy Related, Contraception, Contraceptive Usage","enrollment":25},{"nctId":"NCT04016753","phase":"PHASE1","title":"A Study Measuring the Effectiveness of BMS-986256 Combined With Oral Contraceptive in Healthy Female Participants","status":"COMPLETED","sponsor":"Bristol-Myers Squibb","startDate":"2019-08-05","conditions":"Healthy Participants","enrollment":32},{"nctId":"NCT04934696","phase":"PHASE1","title":"A Study to Characterize the Drug Levels of an Oral Contraceptive With and Without BMS-986166 in Healthy Female Participants of Childbearing Potential","status":"COMPLETED","sponsor":"Bristol-Myers Squibb","startDate":"2021-08-03","conditions":"Healthy Participants","enrollment":25},{"nctId":"NCT02705963","phase":"PHASE1","title":"A Drug-Drug Interaction Study to Assess the Effect of Trametinib on the Pharmacokinetics of an Oral Contraceptive in Female Patients With Solid Tumors","status":"COMPLETED","sponsor":"Novartis Pharmaceuticals","startDate":"2016-10-20","conditions":"Solid Tumors","enrollment":19},{"nctId":"NCT05135013","phase":"","title":"The Association of Hormonal Intake and Demographic Factors With Breast Cancer Risk. An Egyptian Case-controlled Study","status":"UNKNOWN","sponsor":"NewGiza University","startDate":"2021-11-16","conditions":"Observational Study","enrollment":200},{"nctId":"NCT04709094","phase":"PHASE1","title":"A Drug Interaction Study of Danicopan","status":"COMPLETED","sponsor":"Alexion Pharmaceuticals, Inc.","startDate":"2019-07-28","conditions":"Healthy","enrollment":52},{"nctId":"NCT02036879","phase":"EARLY_PHASE1","title":"Gender Disparity and Hormones in Cystic Fibrosis","status":"COMPLETED","sponsor":"University of Texas Southwestern Medical Center","startDate":"2014-02","conditions":"Cystic Fibrosis (CF)","enrollment":55},{"nctId":"NCT03353857","phase":"PHASE1","title":"Drug-drug Interaction Between Rifampicin and Progestins/Ethinylestradiol and Midazolam","status":"COMPLETED","sponsor":"Bayer","startDate":"2017-11-29","conditions":"Biological Availability","enrollment":68},{"nctId":"NCT03262740","phase":"PHASE1","title":"The Effect of BMS-986195 Combined With an Oral Contraceptive (Ethinyl Estradiol/Norethindrone) in Healthy Female Patients","status":"COMPLETED","sponsor":"Bristol-Myers Squibb","startDate":"2017-09-11","conditions":"Rheumatoid Arthritis","enrollment":58},{"nctId":"NCT03262727","phase":"PHASE1","title":"The Effect of BMS-986165 Combined With an Oral Contraceptive (Ethinyl Estradiol/Norethindrone) in Healthy Female Patients","status":"COMPLETED","sponsor":"Bristol-Myers Squibb","startDate":"2017-09-01","conditions":"Systemic Lupus Erythematosus, Arthritic Psoriasis, Psoriasis","enrollment":49},{"nctId":"NCT03856970","phase":"PHASE1","title":"Study to Evaluate the Effect of IW-3718 on the Pharmacokinetics of Oral Contraceptive, Levothyroxine, Glyburide, and Digoxin in Healthy Adult Volunteers","status":"COMPLETED","sponsor":"Ironwood Pharmaceuticals, Inc.","startDate":"2019-03-11","conditions":"Healthy Volunteers","enrollment":87},{"nctId":"NCT01953211","phase":"","title":"Oral Contraceptive Hormone-free Interval Pituitary/ Ovarian Activity","status":"COMPLETED","sponsor":"University of Southern California","startDate":"","conditions":"Hypothalamic-pituitary-ovarian Axis, Gonadotropins, Ethinyl Estradiol, Contraceptive Efficacy","enrollment":64},{"nctId":"NCT02404038","phase":"NA","title":"A Study to Evaluate the Acceptability and Preference for Contraceptive Options as Proxy for HIV Prevention Methods","status":"UNKNOWN","sponsor":"Desmond Tutu HIV Centre","startDate":"2015-07","conditions":"HIV","enrollment":131},{"nctId":"NCT03451110","phase":"PHASE1","title":"Study to Assess the Pharmacokinetic Drug-Drug Interactions of Lemborexant When Coadministered With an Oral Contraceptive, Famotidine, or Fluconazole in Healthy Subjects","status":"COMPLETED","sponsor":"Eisai Inc.","startDate":"2018-02-05","conditions":"Healthy Subjects","enrollment":50},{"nctId":"NCT02480881","phase":"PHASE1","title":"A Drug-drug Interaction Study Between BMS-663068 and Oral Contraceptives in Healthy Female Volunteers (DDI)","status":"COMPLETED","sponsor":"ViiV Healthcare","startDate":"2015-07-07","conditions":"Infection, Human Immunodeficiency Virus","enrollment":26},{"nctId":"NCT01077505","phase":"PHASE1","title":"An Evaluation of the Pharmacokinetics of an Oral Contraceptive (Brevicon) When Co-administered With Albiglutide .","status":"COMPLETED","sponsor":"GlaxoSmithKline","startDate":"2010-03-15","conditions":"Diabetes Mellitus, Type 2","enrollment":16},{"nctId":"NCT02832180","phase":"PHASE1","title":"The Effect of BMS-986142 on the Pharmacokinetics of a Combined Oral Contraceptive (OC) Containing Ethinyl Estradiol (EE) and Norethindrone Acetate (NET) in Healthy Female Subjects","status":"COMPLETED","sponsor":"Bristol-Myers Squibb","startDate":"2016-05","conditions":"Arthritis","enrollment":25},{"nctId":"NCT02652650","phase":"PHASE1","title":"A Study to Investigate the Effect of JNJ-63623872 at Steady-state on the Steady-state Pharmacokinetics of Ethinylestradiol and Norethindrone","status":"COMPLETED","sponsor":"Janssen Research & Development, LLC","startDate":"2015-12","conditions":"Healthy","enrollment":18},{"nctId":"NCT01465022","phase":"NA","title":"Breastfeeding and Oral Contraceptives: a Randomized, Controlled Trial","status":"COMPLETED","sponsor":"University of New Mexico","startDate":"2005-01","conditions":"Breast Feeding, Contraception","enrollment":197},{"nctId":"NCT02170038","phase":"PHASE1","title":"Clinical Study Investigating the Conversion of the Contraceptive Compound Norethisterone Within the Body Towards the Contraceptive Compound Ethinylestradiol","status":"COMPLETED","sponsor":"Bayer","startDate":"2014-06","conditions":"Pharmacokinetics","enrollment":16},{"nctId":"NCT02292732","phase":"PHASE1","title":"A Pharmacokinetics (PK) and Safety Study to Determine the Effect of Repeat Dosing of Trametinib on Combined Oral Contraceptive (Norethindrone Plus Ethinyl Estradiol) in Female Subjects With Solid Tumors","status":"WITHDRAWN","sponsor":"GlaxoSmithKline","startDate":"2016-02","conditions":"Cancer","enrollment":""},{"nctId":"NCT01209143","phase":"PHASE1","title":"A Study of Pharmacokinetic Drug Interaction Study of the Hedgehog Pathway Inhibitor GDC-0449 in Combination With Rosiglitazone or Combined Oral Contraceptive in Patients With Locally Advanced or Metastatic Solid Tumors That Are Refractory to Standard Therapy or for Whom No Standard Therapy Exists","status":"COMPLETED","sponsor":"Genentech, Inc.","startDate":"2010-11","conditions":"Solid Cancers","enrollment":52},{"nctId":"NCT00350480","phase":"NA","title":"Treatment of Non-Gestational Acute Uterine Bleeding: A Randomized Trial","status":"COMPLETED","sponsor":"Kaiser Permanente","startDate":"2003-04","conditions":"Uterine Hemorrhage, Menorrhagia","enrollment":240},{"nctId":"NCT01953809","phase":"PHASE1","title":"A Pharmacokinetics, Pharmacodynamics, and Safety Study of an Oral Contraceptive Containing Norethindrone and Ethinyl Estradiol When Co-administered With GSK1322322 in Healthy Adult Women","status":"WITHDRAWN","sponsor":"GlaxoSmithKline","startDate":"2014-08","conditions":"Infections, Bacterial","enrollment":""},{"nctId":"NCT02245438","phase":"PHASE1","title":"Effect of Tipranavir and Ritonavir on the Pharmacokinetic Characteristics of Norethindrone-Ethinyl Estradiol in Healthy Female Adult Volunteers","status":"TERMINATED","sponsor":"Boehringer Ingelheim","startDate":"2002-05","conditions":"Healthy","enrollment":52},{"nctId":"NCT02103569","phase":"PHASE1","title":"Drug Interaction Study of an OCP (Norethindrone (ND) Acetate and Ethinyl Estradiol (EE))With a Combination of Daclatasvir (DCV) Asunaprevir (ASV) and BMS-791325","status":"COMPLETED","sponsor":"Bristol-Myers Squibb","startDate":"2014-04","conditions":"Hepatitis C","enrollment":20},{"nctId":"NCT02210702","phase":"PHASE4","title":"Oral Contraceptive Ethinyl Estradiol Dose Effect on Postpartum Depression and Sexual Functioning Scales","status":"UNKNOWN","sponsor":"The Jones Institute","startDate":"2014-07","conditions":"Postpartum Depressive Mood, Postpartum Sexual Function","enrollment":33},{"nctId":"NCT02182791","phase":"PHASE1","title":"Investigation of the Potential Pharmacokinetic Interaction Between Nevirapine (VIRAMUNE) and Ethinyl Estradiol/Norethindrone in HIV-1 Infected Women","status":"COMPLETED","sponsor":"Boehringer Ingelheim","startDate":"1998-04","conditions":"HIV Infections","enrollment":14},{"nctId":"NCT00999479","phase":"NA","title":"Post Operative Continuous Active Combination Sex Steroids for the Prevention of Recurrent Endometrioma Formation","status":"WITHDRAWN","sponsor":"University of Oklahoma","startDate":"2009-10","conditions":"Endometrioma","enrollment":""},{"nctId":"NCT00477633","phase":"PHASE3","title":"Study of Safety and Efficacy of an Oral Contraceptive","status":"COMPLETED","sponsor":"Warner Chilcott","startDate":"2007-06","conditions":"Contraception","enrollment":1700},{"nctId":"NCT00391807","phase":"PHASE3","title":"Study of Safety and Efficacy of an Oral Contraceptive","status":"COMPLETED","sponsor":"Warner Chilcott","startDate":"2006-11","conditions":"Contraception","enrollment":1683},{"nctId":"NCT00932321","phase":"PHASE3","title":"Study of Safety and Efficacy of an Oral Contraceptive","status":"COMPLETED","sponsor":"Warner Chilcott","startDate":"2004-01","conditions":"Prevention of Pregnancy","enrollment":938},{"nctId":"NCT01044498","phase":"PHASE3","title":"A Study of Tocilizumab in Combination With an Oral Contraceptive in Patients With Rheumatoid Arthritis","status":"COMPLETED","sponsor":"Hoffmann-La Roche","startDate":"2009-12","conditions":"Rheumatoid Arthritis","enrollment":46},{"nctId":"NCT01486004","phase":"PHASE1","title":"A Study in Healthy Female Participants Investigating the Effect of TMC435 on the Pharmacokinetics of the Synthetic Hormones of the Oral Contraceptive Ovysmen","status":"COMPLETED","sponsor":"Tibotec Pharmaceuticals, Ireland","startDate":"2011-11","conditions":"Hepatitis C Virus","enrollment":18},{"nctId":"NCT01200537","phase":"NA","title":"Optimizing Ovulation Induction in the Poor Responder","status":"WITHDRAWN","sponsor":"Duke University","startDate":"2010-10","conditions":"IVF Poor Responders","enrollment":""},{"nctId":"NCT01597986","phase":"PHASE1","title":"Drug Interaction Study of Isavuconazole and Oral Contraceptive Containing Ethinyl Estradiol and Norethindrone","status":"COMPLETED","sponsor":"Astellas Pharma Global Development, Inc.","startDate":"2012-04","conditions":"Pharmacokinetics of Isavuconazole, Pharmacokinetics of Ethinyl Estradiol and Norethindrone, Healthy Volunteers","enrollment":24},{"nctId":"NCT00504816","phase":"PHASE1","title":"A Study of the Effects of GSK189075 on PK Profiles of an Oral Contraceptive Pill When Given to Healthy Female Volunteers","status":"COMPLETED","sponsor":"GlaxoSmithKline","startDate":"2007-04","conditions":"Type 2 Diabetes Mellitus, Diabetes Mellitus, Type 2","enrollment":22},{"nctId":"NCT01344369","phase":"PHASE1","title":"Norethindrone/Ethinyl Estradiol 0.4 mg/35 Mcg Chewable Tablets Under Non-Fasted Conditions","status":"COMPLETED","sponsor":"Teva Pharmaceuticals USA","startDate":"2008-08","conditions":"Healthy","enrollment":36},{"nctId":"NCT01340625","phase":"PHASE1","title":"Norethindrone/Ethinyl Estradiol 0.4 mg/35 Mcg Chewable Tablets Under Fasting Conditions","status":"COMPLETED","sponsor":"Teva Pharmaceuticals USA","startDate":"2006-12","conditions":"Bioequivalence","enrollment":36},{"nctId":"NCT01036893","phase":"PHASE1","title":"M0001 Effects on Oral Contraceptive Plasma Levels","status":"COMPLETED","sponsor":"Movetis","startDate":"2009-12","conditions":"Healthy Volunteers","enrollment":16},{"nctId":"NCT00000897","phase":"NA","title":"A Study to Evaluate the Effects of Different Methods of Birth Control on the Drug Actions of Zidovudine (an Anti-HIV Drug) in HIV-Positive Women and to Compare Zidovudine Metabolism in Men and Women","status":"COMPLETED","sponsor":"National Institute of Allergy and Infectious Diseases (NIAID)","startDate":"","conditions":"HIV Infections","enrollment":42},{"nctId":"NCT00212277","phase":"PHASE3","title":"Efficacy and Safety,Long-term Study of Low-dose Oral Contraceptive Pill to Treat Dysmenorrhea.","status":"COMPLETED","sponsor":"Nobelpharma","startDate":"2005-02","conditions":"Dysmenorrhea","enrollment":""},{"nctId":"NCT00212342","phase":"PHASE3","title":"Efficacy and Safety Study of Low Dose Oral Contraceptive Pill to Treat Dysmenorrhea","status":"COMPLETED","sponsor":"Nobelpharma","startDate":"2004-12","conditions":"Dysmenorrhea","enrollment":100},{"nctId":"NCT00739622","phase":"PHASE1","title":"TMC278-TiDP6-C136: Effect of TMC278 on Ethinylestradiol and Norethindrone in Healthy Women.","status":"COMPLETED","sponsor":"Tibotec Pharmaceuticals, Ireland","startDate":"2008-07","conditions":"HIV, AIDS, Oral Contraceptive","enrollment":18},{"nctId":"NCT01040845","phase":"PHASE1","title":"A Pharmacokinetic Study of Colchicine With an Oral Contraceptive","status":"COMPLETED","sponsor":"Mutual Pharmaceutical Company, Inc.","startDate":"2007-08","conditions":"Pharmacokinetics","enrollment":30},{"nctId":"NCT00821496","phase":"PHASE1","title":"Evaluate the Effect of VI-0521 on the Pharmacokinetics of Oral Contraceptive in Healthy Female Subjects","status":"COMPLETED","sponsor":"VIVUS LLC","startDate":"2009-01","conditions":"Healthy","enrollment":20},{"nctId":"NCT00732693","phase":"PHASE4","title":"Evaluation of Physiologic and Standard Sex Steroid Replacement Regimens in Women With Premature Ovarian Failure","status":"COMPLETED","sponsor":"University of Edinburgh","startDate":"2002-02","conditions":"Premature Ovarian Failure","enrollment":42},{"nctId":"NCT00338052","phase":"PHASE2","title":"Study of Bleeding With Extended Administration of an Oral Contraceptive","status":"COMPLETED","sponsor":"Warner Chilcott","startDate":"2006-06","conditions":"Contraception","enrollment":207},{"nctId":"NCT00004763","phase":"PHASE2","title":"Phase II Randomized Study of Leuprolide Vs Oral Contraceptive Therapy Vs Leuprolide and Oral Contraceptive Therapy for Ovarian Hyperandrogenism","status":"COMPLETED","sponsor":"National Center for Research Resources (NCRR)","startDate":"1993-01","conditions":"Hyperandrogenism","enrollment":45},{"nctId":"NCT00006133","phase":"NA","title":"Randomized Study of Oral Contraceptives or Hormone Replacement Therapy in Women With Systemic Lupus Erythematosus","status":"COMPLETED","sponsor":"National Center for Research Resources (NCRR)","startDate":"2000-06","conditions":"Systemic Lupus Erythematosus","enrollment":970}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"Norethisterone,Ethinylestradiol","genericName":"Norethisterone,Ethinylestradiol","companyName":"Nobelpharma","companyId":"nobelpharma","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Norethisterone is a progestogen that acts as an agonist of the progesterone receptor, while ethinylestradiol is an estrogen that acts as an agonist of the estrogen receptor. Used for Contraception.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}