{"id":"nonhormonal-vaginal-lubricant","safety":{"commonSideEffects":[{"rate":null,"effect":"Vaginal irritation"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"This is achieved through the use of a nonhormonal lubricant that does not contain estrogen or other hormones. The lubricant helps to reduce vaginal dryness and discomfort, making sexual intercourse more comfortable.","oneSentence":"Nonhormonal vaginal lubricant works by providing moisture to the vagina to reduce friction and discomfort during sexual intercourse.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T01:23:19.163Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Treatment of vaginal dryness and discomfort"}]},"trialDetails":[{"nctId":"NCT00276094","phase":"PHASE3","title":"A Clinical Study to Evaluate Ospemifene in the Treatment of Vulvar and Vaginal Atrophy in Postmenopausal Women","status":"COMPLETED","sponsor":"Shionogi","startDate":"2006-01","conditions":"Atrophy, Vaginal Diseases","enrollment":826}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":5,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["K-Y® Brand Jelly"],"phase":"phase_3","status":"active","brandName":"Nonhormonal vaginal lubricant","genericName":"Nonhormonal vaginal lubricant","companyName":"Shionogi","companyId":"shionogi","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Nonhormonal vaginal lubricant works by providing moisture to the vagina to reduce friction and discomfort during sexual intercourse. Used for Treatment of vaginal dryness and discomfort.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}