{"id":"nivea-topical-cream","safety":{"commonSideEffects":[{"rate":null,"effect":"Local skin irritation or contact dermatitis"},{"rate":null,"effect":"Allergic reaction to fragrance or preservatives"}]},"_chembl":{"chemblId":"CHEMBL2108947","moleculeType":"Unknown"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Nivea is a traditional moisturizing cream containing mineral oil, petrolatum, and other emollients that soften and hydrate the stratum corneum. The occlusive ingredients trap moisture in the skin and protect against environmental irritants, making it suitable for general skin care and mild dermatological conditions.","oneSentence":"Nivea cream provides emollient and moisturizing effects by forming an occlusive barrier on the skin surface to reduce transepidermal water loss.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-27T23:57:18.666Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"General skin moisturization and care"},{"name":"Mild xerosis and dry skin conditions"}]},"trialDetails":[{"nctId":"NCT03939884","phase":"PHASE4","title":"MuscleCare™ Pain Relief Therapy vs. Voltaren® in the Relief of Trapezius Trigger Point Musculoskeletal Pain.","status":"COMPLETED","sponsor":"University of Toronto","startDate":"2017-03-28","conditions":"Pain","enrollment":120}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"Nivea, Topical Cream","genericName":"Nivea, Topical Cream","companyName":"University of Toronto","companyId":"university-of-toronto","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Nivea cream provides emollient and moisturizing effects by forming an occlusive barrier on the skin surface to reduce transepidermal water loss. Used for General skin moisturization and care, Mild xerosis and dry skin conditions.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":1,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}