{"id":"nitroxazepine","rwe":[],"tags":[{"label":"nitroxazepine","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"}],"phase":"unknown","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"sintamil","offLabel":[],"synonyms":["nitroxazepine","nitroxazepine hydrochloride","sintamil","nitroxazepine HCl"],"timeline":[],"approvals":[],"brandName":"Sintamil","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"nitroxazepine","explanation":"Imagine your body's cells have locks on them, and Sintamil has a key that fits into one of those locks. When it binds to the lock, it can affect how the cell works, but we don't know exactly how it does that yet. This is a simplified way of thinking about how Sintamil might work, but more research is needed to understand its full effects.","oneSentence":"Sintamil works by interacting with a specific target in the body, although its exact mechanism is not well understood.","technicalDetail":"Sintamil's mechanism of action is not well characterized, but it is believed to interact with a specific protein or receptor in the body, leading to its therapeutic effects."},"_wikipedia":{"url":"https://en.wikipedia.org/wiki/Nitroxazepine","title":"Nitroxazepine","extract":"Nitroxazepine is a tricyclic antidepressant (TCA) which was introduced by Ciba-Geigy for the treatment of depression in India in 1982. It is also indicated for the treatment of nocturnal enuresis. Nitroxazepine acts as a serotonin-norepinephrine reuptake inhibitor and has similar effects to imipramine, but with certain advantages, such as lower anticholinergic side effects."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/4003","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=nitroxazepine","fields":["publications"],"source":"PubMed/NCBI"},{"id":3,"url":"https://en.wikipedia.org/wiki/Nitroxazepine","fields":["history","overview"],"source":"Wikipedia"}],"_enrichedAt":"2026-03-30T13:00:04.388283","biosimilars":[],"competitors":[],"genericName":"nitroxazepine","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"UNII":"CNU9GY55SI","CHEBI":"CHEBI:135448","UMLSCUI":"C0074570","PUBCHEM_CID":"27857","SECONDARY_CAS_RN":"47439-36-1","MESH_SUPPLEMENTAL_RECORD_UI":"C100140"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":9,"therapeuticAreas":["Other"],"biosimilarFilings":[],"recentPublications":[],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"unknown","modality":"Small Molecule","firstApprovalDate":"","aiSummary":"Nitroxazepine is a tricyclic antidepressant introduced in 1982 for the treatment of depression and nocturnal enuresis. It acts as a serotonin-norepinephrine reuptake inhibitor, similar to imipramine but with lower anticholinergic side effects.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}