{"id":"nigella-sativa-oil","safety":{"commonSideEffects":[{"rate":null,"effect":"Gastrointestinal upset"},{"rate":null,"effect":"Allergic reactions (rare)"}]},"_chembl":null,"_dailymed":{"setId":"3bebd5f6-e5c1-0501-e054-00144ff8d46c","title":"VITILIGO ORGANICS (CULLEN CORYLIFOLIUM WHOLE PLANT, BERBERIS VULGARIS ROOT BARK, NIGELLA SATIVA SEED, ORGANIC COCONUT OIL) OINTMENT [ORGANIC CARE AUSTRALIA PTY LTD]"},"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Nigella sativa (black seed) oil contains thymoquinone and other bioactive compounds that suppress pro-inflammatory cytokines, reduce oxidative stress via free radical scavenging, and modulate immune cell function. 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Syndrome","enrollment":48},{"nctId":"NCT03270280","phase":"PHASE2","title":"Comparison of Salivary Interleukin-1β and Matrix Metalloproteinase-8 Levels in Individuals With Chronic Periodontitis","status":"UNKNOWN","sponsor":"University of Health Sciences Lahore","startDate":"2017-09-11","conditions":"Chronic Periodontitis","enrollment":25},{"nctId":"NCT02407262","phase":"PHASE2","title":"Potential Benefits of Black Seed Oil Supplementation on Asthma Inflammation and Outcomes","status":"COMPLETED","sponsor":"University College, London","startDate":"2015-05","conditions":"Asthma","enrollment":80},{"nctId":"NCT02587910","phase":"PHASE2, PHASE3","title":"Melanole, a Dietary Supplement, for the Treatment of Gastroesophageal Reflux Disease","status":"UNKNOWN","sponsor":"Lebanese American University","startDate":"2015-10","conditions":"GERD","enrollment":170},{"nctId":"NCT00327054","phase":"PHASE1, PHASE2","title":"Effectiveness of Nigella Sativa (Kalonji) Seed in 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effects through its active constituent thymoquinone and other phytochemicals. Used for Inflammatory and autoimmune conditions (traditional use), Metabolic syndrome and diabetes (investigational), Respiratory and allergic conditions (traditional use).","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":3,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}