{"id":"nifurprazine","rwe":[{"pmid":"10571254","year":"1999","title":"Nitrofuran drugs as common subversive substrates of Trypanosoma cruzi lipoamide dehydrogenase and trypanothione reductase.","finding":"","journal":"Biochemical pharmacology","studyType":"Clinical Study"},{"pmid":"936836","year":"1976","title":"[Microbiological demonstration of nifurprazine in body fluids and tissues of cattle].","finding":"","journal":"Zentralblatt fur Veterinarmedizin. Reihe B. Journal of veterinary medicine. Series B","studyType":"Clinical Study"},{"pmid":"4424402","year":"1974","title":"[Contact allergy caused by nitrofurazone (furacine) and nifurprazine (carofur)].","finding":"","journal":"Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete","studyType":"Clinical Study"},{"pmid":"5799169","year":"1969","title":"[Contact allergies due to nifurprazine (Carofur)].","finding":"","journal":"Deutsche medizinische Wochenschrift (1946)","studyType":"Clinical Study"}],"tags":[{"label":"nifurprazine","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"furenazin","offLabel":[],"synonyms":["nifurprazine","furenapyridazin","furenazin"],"timeline":[],"approvals":[],"brandName":"Furenazin","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"nifurprazine","explanation":"Think of Furenazin like a strong disinfectant for your body. It helps to stop the growth of bad bacteria, viruses, and other microorganisms that can cause infections. This helps to prevent the spread of infection and promote healing.","oneSentence":"Furenazin works by inhibiting the growth of microorganisms through its antimicrobial properties.","technicalDetail":"Nifurprazine is a sulfonamide antimicrobial agent that exerts its effects by inhibiting the synthesis of folic acid in microorganisms, thereby disrupting their metabolic processes and ultimately leading to their death."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/3796","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=NIFURPRAZINE","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T14:39:43.491478","biosimilars":[],"competitors":[],"genericName":"nifurprazine","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"UNII":"72ZUT1JIEB","CHEBI":"CHEBI:134945","INN_ID":"2062","UMLSCUI":"C2983968","ChEMBL_ID":"CHEMBL2105219","PUBCHEM_CID":"6436113","IUPHAR_LIGAND_ID":"10837"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":4,"therapeuticAreas":["Metabolic"],"biosimilarFilings":[],"recentPublications":[{"date":"1999 Dec 1","pmid":"10571254","title":"Nitrofuran drugs as common subversive substrates of Trypanosoma cruzi lipoamide dehydrogenase and trypanothione reductase.","journal":"Biochemical pharmacology"},{"date":"1976 May","pmid":"936836","title":"[Microbiological demonstration of nifurprazine in body fluids and tissues of cattle].","journal":"Zentralblatt fur Veterinarmedizin. Reihe B. Journal of veterinary medicine. Series B"},{"date":"1974 Aug","pmid":"4424402","title":"[Contact allergy caused by nitrofurazone (furacine) and nifurprazine (carofur)].","journal":"Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete"},{"date":"1969 Aug 22","pmid":"5799169","title":"[Contact allergies due to nifurprazine (Carofur)].","journal":"Deutsche medizinische Wochenschrift (1946)"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Furenazin, also known as Nifurprazine, is a small molecule drug in the nifurprazine class. Unfortunately, there is limited information available on this compound. It is not clear what specific target or indication it is intended to treat. The commercial status of Furenazin is also unknown, and it may not be FDA-approved. Further research is needed to determine its safety and efficacy.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}