{"id":"nifuradene","rwe":[],"tags":[{"label":"nifuradene","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"nifuraden","offLabel":[],"synonyms":["nifuraden","nifuradine","oxafuradene","nifuradene"],"timeline":[],"approvals":[],"brandName":"Nifuraden","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"nifuradene","explanation":"Imagine your body is a garden, and microorganisms are weeds. Nifuradene is like a weed killer that helps prevent the weeds from growing and spreading. It does this by interfering with the way the microorganisms make energy, ultimately killing them or preventing them from causing harm.","oneSentence":"Nifuradene is thought to work by inhibiting the growth of microorganisms through its antimicrobial properties.","technicalDetail":"Nifuradene is a thiazolyl dithiocarbazate compound that likely exerts its antimicrobial effects by disrupting the synthesis of essential biomolecules, such as DNA and proteins, in microorganisms."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/3795","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=NIFURADENE","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T15:09:06.528736","biosimilars":[],"competitors":[],"genericName":"nifuradene","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"UNII":"2VX65207DR","CHEBI":"CHEBI:82352","INN_ID":"2051","UMLSCUI":"C2827289","ChEMBL_ID":"CHEMBL265442","KEGG_DRUG":"D02514","PUBCHEM_CID":"9568055"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":3,"therapeuticAreas":["Other"],"biosimilarFilings":[],"recentPublications":[],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Nifuraden is a small molecule with the synonyms NF-246, NIFURADENE, NIFURADENO, NSC-6470, and OXAFURADENE.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}