{"id":"nicoderm-c-q-transdermal-product","safety":{"commonSideEffects":[{"rate":"15-20","effect":"Skin irritation at patch site"},{"rate":"10-15","effect":"Headache"},{"rate":"5-10","effect":"Nausea"},{"rate":"5-10","effect":"Dizziness"},{"rate":"5-10","effect":"Sleep disturbances"},{"rate":"5","effect":"Vivid dreams"}]},"_chembl":{"chemblId":"CHEMBL2094006","moleculeType":"Small molecule","molecularWeight":"702.93"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"The transdermal patch provides a steady, controlled release of nicotine through the skin into the bloodstream, bypassing the lungs and avoiding combustion byproducts. This maintains nicotine levels to suppress cravings and withdrawal symptoms while the user gradually reduces dependence. The patch is typically used as part of a comprehensive smoking cessation program.","oneSentence":"Nicoderm CQ delivers nicotine transdermally to replace nicotine from cigarettes and reduce withdrawal symptoms during smoking cessation.","_ai_confidence":"high"},"_scrapedAt":"2026-03-27T23:57:05.472Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Smoking cessation aid for nicotine dependence"}]},"trialDetails":[{"nctId":"NCT06161675","phase":"NA","title":"Feasibility of Delivering VergeRx at FQHCs","status":"ACTIVE_NOT_RECRUITING","sponsor":"University of Virginia","startDate":"2024-09-23","conditions":"Tobacco Use Cessation","enrollment":100},{"nctId":"NCT05660525","phase":"NA","title":"Leveraging Community Pharmacists to Optimize Smoking Cessation Services for Rural Smokers in Appalachia","status":"RECRUITING","sponsor":"University of Virginia","startDate":"2024-03-06","conditions":"Smoking Cessation, Smoking, Cigarette, Smoking Reduction","enrollment":768},{"nctId":"NCT04038255","phase":"PHASE4","title":"Mindfulness Based Smoking Cessation Among Cancer Survivors","status":"TERMINATED","sponsor":"University of Miami","startDate":"2019-09-28","conditions":"Tobacco Smoking","enrollment":20},{"nctId":"NCT01943994","phase":"NA","title":"Psilocybin-facilitated Smoking Cessation Treatment: A Pilot Study","status":"COMPLETED","sponsor":"Johns Hopkins University","startDate":"2008-09","conditions":"Nicotine Dependence","enrollment":82},{"nctId":"NCT04994444","phase":"PHASE2, PHASE3","title":"Preloading With Nicotine Replacement Therapy in HIV-positive Smokers to Improve Self-Efficacy and Quit Attempts","status":"COMPLETED","sponsor":"Brown University","startDate":"2021-09-01","conditions":"Tobacco Use Cessation","enrollment":49},{"nctId":"NCT03999411","phase":"PHASE4","title":"Smartphone Intervention for Smoking Cessation and Improving Adherence to Treatment Among HIV Patients","status":"COMPLETED","sponsor":"University of Miami","startDate":"2019-09-09","conditions":"Smoking, Smoking Cessation, HIV","enrollment":39},{"nctId":"NCT05024747","phase":"PHASE1","title":"A Bioequivalence Study of 21 Milligram (mg) Nicotine Transdermal Patches (NicoDerm CQ, GlaxoSmithKline [GSK] Dungarvan) Compared to the Current Marketed 21 mg Nicotine Transdermal Patches (NicoDerm CQ, Alza) in Healthy Adult Smokers","status":"COMPLETED","sponsor":"HALEON","startDate":"2021-09-01","conditions":"Tobacco Use Disorder","enrollment":22},{"nctId":"NCT04286295","phase":"NA","title":"Cytisine Compared to Combination NRT in Relapsed Smokers","status":"TERMINATED","sponsor":"Ottawa Heart Institute Research Corporation","startDate":"2022-03-14","conditions":"Smoking Cessation, Coronary Artery Disease","enrollment":13},{"nctId":"NCT04606797","phase":"PHASE4","title":"Targeting Mailed Nicotine Patch Distribution Interventions to Rural Regions of Canada","status":"COMPLETED","sponsor":"Centre for Addiction and Mental Health","startDate":"2020-11-23","conditions":"Tobacco Use Cessation","enrollment":498},{"nctId":"NCT01372254","phase":"PHASE1, PHASE2","title":"Behavioral Intervention for Low Income Depressed Smokers in Drug Treatment","status":"COMPLETED","sponsor":"University of Maryland, College Park","startDate":"2011-12","conditions":"Cigarette Smoking, Drug Use","enrollment":96},{"nctId":"NCT02482233","phase":"PHASE4","title":"The END Perioperative Smoking Pilot Study","status":"COMPLETED","sponsor":"University of California, San Francisco","startDate":"2015-08","conditions":"Smoking, Nicotine Addiction, Surgery","enrollment":30},{"nctId":"NCT02982772","phase":"NA","title":"Patch Study - Intervention for HIV Positive Smokers","status":"COMPLETED","sponsor":"dr. maria miguez","startDate":"2016-05","conditions":"Smoking Cessation, HIV","enrollment":488},{"nctId":"NCT04534231","phase":"","title":"Offering Nicotine Patches to All Households in a Municipality With High Smoking Rates","status":"COMPLETED","sponsor":"Centre for Addiction and Mental Health","startDate":"2020-10-19","conditions":"Tobacco Use Cessation","enrollment":123},{"nctId":"NCT01944423","phase":"EARLY_PHASE1","title":"Enhancing Panic and Smoking Reduction Treatment With D-Cycloserine","status":"COMPLETED","sponsor":"University of Texas at Austin","startDate":"2013-10","conditions":"Nicotine Addiction, Panic Attack","enrollment":53},{"nctId":"NCT00699556","phase":"PHASE2","title":"Do Treatments for Smoking Cessation Affect Alcohol Drinking? Study 1: Nicotine Replacement Therapy","status":"COMPLETED","sponsor":"Yale University","startDate":"2006-01","conditions":"Alcohol Drinking","enrollment":22},{"nctId":"NCT00352781","phase":"NA","title":"Stop Smoking Therapy for Ontario Patients","status":"COMPLETED","sponsor":"Centre for Addiction and Mental Health","startDate":"2006-07","conditions":"Smoking","enrollment":1767},{"nctId":"NCT01989923","phase":"NA","title":"Smoking Cessation in Women With Gynecological Conditions","status":"COMPLETED","sponsor":"University of Oklahoma","startDate":"2013-06","conditions":"Cervical Dysplasia","enrollment":31},{"nctId":"NCT01314001","phase":"PHASE3","title":"Pharmacogenetics of Nicotine Addiction Treatment","status":"COMPLETED","sponsor":"University of Pennsylvania","startDate":"2010-12","conditions":"Nicotine Addiction","enrollment":1246},{"nctId":"NCT01800019","phase":"PHASE3","title":"The Canadian HIV Quit Smoking Trial: Tackling the Co-morbidities of Depression and Cardiovascular Disease in HIV+ Smokers","status":"UNKNOWN","sponsor":"Ottawa Hospital Research Institute","startDate":"2014-01","conditions":"HIV, Smoking Cessation","enrollment":256},{"nctId":"NCT01429129","phase":"PHASE4","title":"Randomized Controlled Trial of Mailed Nicotine Replacement Therapy to Canadian Smokers","status":"COMPLETED","sponsor":"Centre for Addiction and Mental Health","startDate":"2012-05","conditions":"Smoking","enrollment":1000},{"nctId":"NCT00224419","phase":"PHASE4","title":"Testing Pharmacological Therapies for Pregnant Smokers","status":"TERMINATED","sponsor":"Duke University","startDate":"2003-06","conditions":"Smoking, Pregnancy","enrollment":181},{"nctId":"NCT00990197","phase":"NA","title":"The Safety of Transdermal Nicotine Immediately Following an Acute Coronary Syndrome","status":"SUSPENDED","sponsor":"Sir Mortimer B. Davis - Jewish General Hospital","startDate":"2005-06","conditions":"Smoking Cessation","enrollment":30}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["NRT","NRT+"],"phase":"marketed","status":"active","brandName":"Nicoderm C-Q Transdermal Product","genericName":"Nicoderm C-Q Transdermal Product","companyName":"University of Miami","companyId":"university-of-miami","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Nicoderm CQ delivers nicotine transdermally to replace nicotine from cigarettes and reduce withdrawal symptoms during smoking cessation. Used for Smoking cessation aid for nicotine dependence.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":3,"withResults":2},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}