{"id":"niceritrol","rwe":[{"pmid":"24383936","year":"2014","title":"A novel method aimed at counteracting the side effects caused by prostaglandin e2 deficiency during non-steroidal anti-inflammatory drug therapy.","finding":"","journal":"Anti-inflammatory & anti-allergy agents in medicinal chemistry","studyType":"Clinical Study"},{"pmid":"20842518","year":"2010","title":"Successful treatment of lipoprotein glomerulopathy in a daughter and a mother using niceritrol.","finding":"","journal":"Clinical and experimental nephrology","studyType":"Clinical Study"},{"pmid":"17001111","year":"2006","title":"Effect of levothyroxine on total lipid profiles as assessed by analytical capillary isotachophoresis in a patient with hypothyroidism.","finding":"","journal":"Endocrine journal","studyType":"Clinical Study"},{"pmid":"12714122","year":"2003","title":"Antiproteinuric effect of niceritrol, a nicotinic acid derivative, in chronic renal disease with hyperlipidemia: a randomized trial.","finding":"","journal":"The American journal of medicine","studyType":"Clinical Study"},{"pmid":"12500244","year":"2003","title":"Resolution of typical lipoprotein glomerulopathy by intensive lipid-lowering therapy.","finding":"","journal":"American journal of kidney diseases : the official journal of the National Kidney Foundation","studyType":"Clinical Study"}],"tags":[{"label":"niceritrol","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"C10AD01","category":"atc"},{"label":"Active","category":"status"},{"label":"Antimetabolites","category":"pharmacology"},{"label":"Hypolipidemic Agents","category":"pharmacology"},{"label":"Lipid Regulating Agents","category":"pharmacology"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"perycit","offLabel":[],"synonyms":["pentaerythritoltetranicotinate","niceritrol tetrahydrochloride","niceritrol","nicotinic acid neopentanetetrayl ester","pentaerythritol tetranicotinate","perycit"],"timeline":[],"approvals":[],"brandName":"Perycit","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"niceritrol","explanation":"Imagine your body's cells are like a orchestra, and Perycit is like a conductor that helps the cells work together to produce a specific outcome. However, the exact way it conducts the cells is not yet fully understood. More research is needed to determine how Perycit produces its effects.","oneSentence":"Perycit is thought to work by interacting with cellular targets to produce a therapeutic effect.","technicalDetail":"Perycit is a small molecule that binds to specific cellular targets, potentially influencing downstream signaling pathways to produce its therapeutic effects."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/1911","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=NICERITROL","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T14:38:42.722018","biosimilars":[],"competitors":[{"drugName":"nicotinic acid","drugSlug":"nicotinic-acid","fdaApproval":"1957-07-24","relationship":"same-class"}],"genericName":"niceritrol","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[{"drugId":"nicotinic-acid","brandName":"nicotinic acid","genericName":"nicotinic acid","approvalYear":"1957","relationship":"same-class"}],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"MMSL":"2275","NDDF":"001052","UNII":"F54EHJ34MV","CHEBI":"CHEBI:31903","VANDF":"4017661","INN_ID":"2849","RXNORM":"7393","UMLSCUI":"C0028009","ChEMBL_ID":"CHEMBL1697762","KEGG_DRUG":"D01754","DRUGBANK_ID":"DB13441","PDB_CHEM_ID":" NIO","PUBCHEM_CID":"4476","SNOMEDCT_US":"273943001","MESH_DESCRIPTOR_UI":"D009531"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":53,"therapeuticAreas":["Other"],"atcClassification":{"source":"DrugCentral","atcCode":"C10AD01","allCodes":["C10AD01"]},"biosimilarFilings":[],"recentPublications":[{"date":"2014","pmid":"24383936","title":"A novel method aimed at counteracting the side effects caused by prostaglandin e2 deficiency during non-steroidal anti-inflammatory drug therapy.","journal":"Anti-inflammatory & anti-allergy agents in medicinal chemistry"},{"date":"2010 Dec","pmid":"20842518","title":"Successful treatment of lipoprotein glomerulopathy in a daughter and a mother using niceritrol.","journal":"Clinical and experimental nephrology"},{"date":"2006 Dec","pmid":"17001111","title":"Effect of levothyroxine on total lipid profiles as assessed by analytical capillary isotachophoresis in a patient with hypothyroidism.","journal":"Endocrine journal"},{"date":"2003 Apr 1","pmid":"12714122","title":"Antiproteinuric effect of niceritrol, a nicotinic acid derivative, in chronic renal disease with hyperlipidemia: a randomized trial.","journal":"The American journal of medicine"},{"date":"2003 Jan","pmid":"12500244","title":"Resolution of typical lipoprotein glomerulopathy by intensive lipid-lowering therapy.","journal":"American journal of kidney diseases : the official journal of the National Kidney Foundation"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Perycit, also known as NICERITROL, is a small molecule drug in the niceritrol class. Its exact target and mechanism of action are unknown, and it has not been approved by the FDA for any indications. The commercial status of Perycit is unclear, and it is not known whether it is patented or available as a generic. Further research is needed to determine its safety and efficacy. As a result, Perycit is not currently available for clinical use.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}