{"id":"nicametate","rwe":[{"pmid":"34315990","year":"2021","title":"Impacts of treatments on recurrence and 28-year survival of ischemic stroke patients.","finding":"","journal":"Scientific reports","studyType":"Clinical Study"},{"pmid":"9700242","year":"1998","title":"Pharmacologic agents inhibit rat mesangial cell proliferation and collagen synthesis.","finding":"","journal":"Journal of the Formosan Medical Association = Taiwan yi zhi","studyType":"Clinical Study"},{"pmid":"9259112","year":"1997","title":"Effectiveness of low-dose ASA in prevention of secondary ischemic stroke, the ASA Study Group in Taiwan.","finding":"","journal":"Thrombosis research","studyType":"Clinical Study"},{"pmid":"6307192","year":"1983","title":"Plasma guanosine 3',5'-monophosphate responses to the cold pressor test in patients with vibration disease.","finding":"","journal":"Archives of environmental health","studyType":"Clinical Study"},{"pmid":"4211730","year":"1973","title":"[Use of citrate nicamétate at high doses in cardiovascular surgery].","finding":"","journal":"Lille medical : journal de la Faculte de medecine et de pharmacie de l'Universite de Lille","studyType":"Clinical Study"}],"tags":[{"label":"nicametate","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"},{"label":"Cardiovascular Agents","category":"pharmacology"},{"label":"Vasodilator Agents","category":"pharmacology"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"beta-diethylaminoethyl nicotinate","offLabel":[],"synonyms":["nicametate","beta-Diethylaminoethyl nicotinate"],"timeline":[],"approvals":[],"brandName":"Beta-Diethylaminoethyl Nicotinate","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"nicametate","explanation":"Imagine your body's cells have special locks called nicotinic receptors. Beta-Diethylaminoethyl Nicotinate is a key that fits into these locks, helping to regulate various bodily functions. This interaction can have different effects depending on the specific lock and the body's needs.","oneSentence":"Beta-Diethylaminoethyl Nicotinate works by interacting with nicotinic receptors in the body.","technicalDetail":"Beta-Diethylaminoethyl Nicotinate acts as a nicotinic receptor agonist, binding to nicotinic acetylcholine receptors and modulating their activity, which can lead to various downstream effects on the body."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/3793","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=NICAMETATE","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T14:38:36.950907","biosimilars":[],"competitors":[],"genericName":"nicametate","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"NDDF":"007535","UNII":"ML4O3WYO2M","CHEBI":"CHEBI:134915","INN_ID":"1969","UMLSCUI":"C0068677","ChEMBL_ID":"CHEMBL1907110","KEGG_DRUG":"D08269","PUBCHEM_CID":"71650","MESH_SUPPLEMENTAL_RECORD_UI":"C005392"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":6,"therapeuticAreas":["Other"],"biosimilarFilings":[],"recentPublications":[{"date":"2021 Jul 27","pmid":"34315990","title":"Impacts of treatments on recurrence and 28-year survival of ischemic stroke patients.","journal":"Scientific reports"},{"date":"1998 Jul","pmid":"9700242","title":"Pharmacologic agents inhibit rat mesangial cell proliferation and collagen synthesis.","journal":"Journal of the Formosan Medical Association = Taiwan yi zhi"},{"date":"1997 Jul 15","pmid":"9259112","title":"Effectiveness of low-dose ASA in prevention of secondary ischemic stroke, the ASA Study Group in Taiwan.","journal":"Thrombosis research"},{"date":"1983 May-Jun","pmid":"6307192","title":"Plasma guanosine 3',5'-monophosphate responses to the cold pressor test in patients with vibration disease.","journal":"Archives of environmental health"},{"date":"1973 Nov","pmid":"4211730","title":"[Use of citrate nicamétate at high doses in cardiovascular surgery].","journal":"Lille medical : journal de la Faculte de medecine et de pharmacie de l'Universite de Lille"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Beta-Diethylaminoethyl Nicotinate (NICAMETATE) is a small molecule nicametate drug with unknown target and FDA approval status. It is used to treat unknown indications. The commercial status of NICAMETATE is unclear, with unknown generic manufacturers and patent status. Key safety considerations are also unknown. Further research is needed to understand the pharmacology and clinical use of NICAMETATE.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}