{"id":"neisvac-c-vaccine-12mth","safety":{"commonSideEffects":[{"rate":"10-30","effect":"Local injection site reactions (erythema, swelling, pain)"},{"rate":"5-15","effect":"Fever"},{"rate":"5-10","effect":"Irritability"},{"rate":"5-10","effect":"Drowsiness"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"The vaccine contains purified polysaccharide from the meningococcal serogroup C capsule conjugated to a protein carrier, which enhances immunogenicity and T-cell dependent immune response. This allows the vaccine to induce both IgG antibodies and immunological memory, providing protection against invasive meningococcal disease caused by serogroup C strains. The conjugate formulation is particularly effective in infants and young children who would otherwise have poor response to unconjugated polysaccharide vaccines.","oneSentence":"NeisVac C is a conjugate vaccine that stimulates the immune system to produce antibodies against Neisseria meningitidis serogroup C polysaccharide capsule.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-27T23:35:00.242Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Prevention of invasive meningococcal disease caused by Neisseria meningitidis serogroup C in infants and young children"}]},"trialDetails":[{"nctId":"NCT00936962","phase":"PHASE4","title":"Evaluation of Meningococcal C Vaccine Programmes in Canadian Children","status":"COMPLETED","sponsor":"University of British Columbia","startDate":"2009-07","conditions":"Meningococcal Sero-type C Infection","enrollment":452}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["NeisVac C vaccine (Baxter)","Meningococcal C congugate vaccine"],"phase":"marketed","status":"active","brandName":"NeisVac C vaccine (12mth)","genericName":"NeisVac C vaccine (12mth)","companyName":"University of British Columbia","companyId":"university-of-british-columbia","modality":"Biologic","firstApprovalDate":"","aiSummary":"NeisVac C is a conjugate vaccine that stimulates the immune system to produce antibodies against Neisseria meningitidis serogroup C polysaccharide capsule. Used for Prevention of invasive meningococcal disease caused by Neisseria meningitidis serogroup C in infants and children.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}