{"id":"nebulized-morphine","safety":{"commonSideEffects":[{"rate":"null","effect":"Respiratory depression"},{"rate":"10-20%","effect":"Nausea"},{"rate":"5-10%","effect":"Vomiting"},{"rate":"5-10%","effect":"Dizziness"},{"rate":"5-10%","effect":"Headache"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"Morphine binds to opioid receptors in the lungs, which helps to reduce pain perception. This is achieved by activating the mu-opioid receptor, leading to a decrease in the transmission of pain signals to the brain.","oneSentence":"Nebulized morphine works by releasing morphine into the lungs to provide pain relief.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T00:50:29.255Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Acute pain"},{"name":"Cough"}]},"trialDetails":[{"nctId":"NCT03580187","phase":"PHASE3","title":"Nebulized Morphine in Chest Trauma Patients: A Prospective Study","status":"COMPLETED","sponsor":"University Hospital, Mahdia","startDate":"2018-06-14","conditions":"Blunt Injury of Thorax","enrollment":75},{"nctId":"NCT04497831","phase":"PHASE3","title":"Morphine for Dyspnea in Pulmonary Fibrosis","status":"UNKNOWN","sponsor":"Medical University of Gdansk","startDate":"2020-09-21","conditions":"Idiopathic Pulmonary Fibrosis (IPF)","enrollment":20},{"nctId":"NCT02156596","phase":"PHASE1","title":"IV NSAI Versus Nebulized Morphine Analgesia for First-line Renal Colic","status":"COMPLETED","sponsor":"University of Monastir","startDate":"2013-02","conditions":"Renal Colic","enrollment":100},{"nctId":"NCT01975753","phase":"PHASE1, PHASE2","title":"First Evaluation of Morphine Hydrochloride by Nebulisation in Healthy Volunteers","status":"COMPLETED","sponsor":"University Hospital, Rouen","startDate":"2014-05-13","conditions":"Acute Pain","enrollment":35},{"nctId":"NCT02624089","phase":"PHASE1, PHASE2","title":"Nebulized Analgesia for Laparoscopic Appendectomy Trial","status":"UNKNOWN","sponsor":"McGill University Health Centre/Research Institute of the McGill University Health Centre","startDate":"2016-01","conditions":"Appendicitis","enrollment":200},{"nctId":"NCT02200185","phase":"NA","title":"Titrated Versus High and Low Dose Nebulized Morphine to Reduce Pain in Emergency Settings","status":"COMPLETED","sponsor":"University of Monastir","startDate":"2012-04","conditions":"Post-Traumatic Headache, Acute Pain","enrollment":300},{"nctId":"NCT01123551","phase":"PHASE3","title":"Efficacy Study of Nebulized Morphine and Intravenous Morphine in Post Traumatic Pain","status":"COMPLETED","sponsor":"University of Monastir","startDate":"2010-06","conditions":"Post Traumatic Pain","enrollment":200}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":54,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"nebulized morphine","genericName":"nebulized morphine","companyName":"University of Monastir","companyId":"university-of-monastir","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Nebulized morphine works by releasing morphine into the lungs to provide pain relief. Used for Acute pain, Cough.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}