{"id":"nebulized-heparin-and-salbutamol","safety":{"commonSideEffects":[{"rate":null,"effect":"Tremor"},{"rate":null,"effect":"Tachycardia"},{"rate":null,"effect":"Headache"},{"rate":null,"effect":"Throat irritation"},{"rate":null,"effect":"Bleeding risk (minor)"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Heparin is an anticoagulant that also possesses anti-inflammatory properties when inhaled, helping to reduce airway inflammation and mucus production. Salbutamol is a beta-2 agonist bronchodilator that relaxes airway smooth muscle and improves airflow. The combination is used to manage respiratory conditions characterized by both airway obstruction and inflammatory/thrombotic components.","oneSentence":"Nebulized heparin and salbutamol work together to reduce airway inflammation and prevent thrombosis while bronchodilating the airways.","_ai_confidence":"low"},"_scrapedAt":"2026-03-27T23:56:49.911Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Acute exacerbation of chronic obstructive pulmonary disease (COPD)"},{"name":"Cystic fibrosis with airway inflammation"},{"name":"Acute asthma exacerbation with inflammatory component"}]},"trialDetails":[{"nctId":"NCT03333395","phase":"PHASE4","title":"Nebulized Heparin and Salbutamol in Mechanically Ventilated Patients With AECOPD","status":"COMPLETED","sponsor":"Ain Shams University","startDate":"2017-02-01","conditions":"Mechanically Ventilated Patients","enrollment":60}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"Nebulized heparin and salbutamol","genericName":"Nebulized heparin and salbutamol","companyName":"Ain Shams University","companyId":"ain-shams-university","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Nebulized heparin and salbutamol work together to reduce airway inflammation and prevent thrombosis while bronchodilating the airways. Used for Cystic fibrosis with airway inflammation, Chronic obstructive pulmonary disease with inflammatory component.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":1,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}