{"id":"nanos1-argent-collo-dal","safety":{"commonSideEffects":[{"rate":null,"effect":"Argyria (blue-gray skin discoloration)"},{"rate":null,"effect":"Gastrointestinal disturbance"},{"rate":null,"effect":"Allergic reactions"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Colloidal silver (argent colloïdal) consists of silver nanoparticles suspended in a liquid medium. These particles are believed to disrupt microbial cell walls, inhibit enzyme function, and interfere with DNA replication in bacteria and fungi. The exact mechanism in human therapeutic use remains incompletely characterized, particularly for systemic applications.","oneSentence":"Colloidal silver exerts antimicrobial effects through direct interaction with bacterial and fungal cell membranes and nucleic acids.","_ai_confidence":"low"},"_scrapedAt":"2026-03-28T01:22:38.186Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Bacterial or fungal infections (specific indication unclear from available information)"}]},"trialDetails":[{"nctId":"NCT05822180","phase":"PHASE3","title":"Evaluation of the Efficacy and Safety of Nano-S1","status":"COMPLETED","sponsor":"General Administration of Military Health, Tunisia","startDate":"2021-01-01","conditions":"COVID-19 Pneumonia","enrollment":116}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"NANOS1 , argent colloïdal ,","genericName":"NANOS1 , argent colloïdal ,","companyName":"General Administration of Military Health, Tunisia","companyId":"general-administration-of-military-health-tunisia","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Colloidal silver exerts antimicrobial effects through direct interaction with bacterial and fungal cell membranes and nucleic acids. Used for Bacterial or fungal infections (specific indication unclear from available information).","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}