{"id":"nacl-0-9-in-glucose-5-40mmol-l-potassium","safety":{"commonSideEffects":[{"rate":null,"effect":"Hyperkalemia (if renal function impaired)"},{"rate":null,"effect":"Hyponatremia (with excessive administration)"},{"rate":null,"effect":"Phlebitis at infusion site"},{"rate":null,"effect":"Hyperglycemia (in diabetic patients)"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"The formulation combines isotonic saline (0.9% NaCl) with 5% glucose to provide both electrolyte replacement and a modest caloric source, while the 40 mmol/L potassium supplementation addresses hypokalemia or prevents potassium depletion during fluid therapy. This is a standard parenteral nutrition/rehydration solution used to maintain or restore normal serum electrolyte concentrations and intravascular volume.","oneSentence":"This intravenous fluid replacement solution provides sodium chloride, glucose, and potassium to restore electrolyte balance and provide hydration and calories.","_ai_confidence":"high"},"_scrapedAt":"2026-03-27T23:34:48.661Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Hypovolemia and dehydration requiring intravenous fluid replacement"},{"name":"Hypokalemia or potassium depletion prevention during fluid therapy"},{"name":"Maintenance of electrolyte and fluid balance in hospitalized patients"}]},"trialDetails":[{"nctId":"NCT03080831","phase":"PHASE4","title":"TOnicity of Perioperative Maintenance SoluTions","status":"COMPLETED","sponsor":"Niels Van Regenmortel","startDate":"2017-03-09","conditions":"Thoracic Diseases, Water-Electrolyte Imbalance, Fluid Overload","enrollment":70}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"NaCl 0.9% in Glucose 5% + 40mmol/L Potassium","genericName":"NaCl 0.9% in Glucose 5% + 40mmol/L Potassium","companyName":"Niels Van Regenmortel","companyId":"niels-van-regenmortel","modality":"Small molecule","firstApprovalDate":"","aiSummary":"This intravenous fluid replacement solution provides sodium chloride, glucose, and potassium to restore electrolyte balance and provide hydration and calories. Used for Fluid and electrolyte replacement in dehydration, Maintenance therapy in patients unable to take oral intake, Hypokalemia correction.","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}