{"id":"mylan-generic-fentanyl","safety":{"commonSideEffects":[{"rate":null,"effect":"Respiratory depression"},{"rate":null,"effect":"Sedation"},{"rate":null,"effect":"Nausea"},{"rate":null,"effect":"Constipation"},{"rate":null,"effect":"Dizziness"},{"rate":null,"effect":"Pruritus"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Fentanyl acts as an agonist at mu (μ) opioid receptors, which are G-protein coupled receptors distributed throughout the brain and spinal cord. This binding modulates pain perception and produces analgesic and sedative effects. It is approximately 50-100 times more potent than morphine on a weight basis.","oneSentence":"Fentanyl is a synthetic opioid that binds to mu opioid receptors in the central nervous system to produce analgesia and sedation.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T00:41:35.004Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Moderate to severe acute pain"},{"name":"Chronic pain in opioid-tolerant patients"},{"name":"Perioperative analgesia and sedation"}]},"trialDetails":[{"nctId":"NCT02531971","phase":"PHASE4","title":"Fentanyl Patch Pharmacokinetics in Healthy Adults","status":"COMPLETED","sponsor":"University of Maryland, Baltimore","startDate":"2016-01-14","conditions":"Peer Review, Research","enrollment":24},{"nctId":"NCT02486016","phase":"PHASE4","title":"Transdermal Patch CVD 2000: The Effect of Heat on Fentanyl Release From Fentanyl TDSs in Healthy Adults","status":"COMPLETED","sponsor":"University of Maryland, Baltimore","startDate":"2015-07-09","conditions":"Peer Review, Research","enrollment":10}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":4,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["Mylan generic fentanyl skin patch"],"phase":"marketed","status":"active","brandName":"Mylan generic fentanyl","genericName":"Mylan generic fentanyl","companyName":"University of Maryland, Baltimore","companyId":"university-of-maryland-baltimore","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Fentanyl is a synthetic opioid agonist that binds to mu-opioid receptors in the central nervous system to produce analgesia and sedation. Used for Moderate to severe acute pain, Chronic pain management, Cancer pain.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":1,"withResults":1},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}