{"id":"multiple-cardiovascular-drugs-related-to-golden-triangle","_fda":{"id":"b8f5797b-73e1-4201-b824-2cdd50c90497","set_id":"00002127-02bc-4c66-b0c3-ca29d8224afc","openfda":{"nui":["N0000175486","M0011640"],"upc":["0367618160039"],"unii":["85H0HZU99M"],"route":["TOPICAL"],"rxcui":["108204","238850"],"spl_id":["b8f5797b-73e1-4201-b824-2cdd50c90497"],"brand_name":["Betadine"],"spl_set_id":["00002127-02bc-4c66-b0c3-ca29d8224afc"],"package_ndc":["67618-192-03"],"product_ndc":["67618-192"],"generic_name":["POVIDONE-IODINE"],"product_type":["HUMAN OTC DRUG"],"pharm_class_cs":["Iodine [CS]"],"substance_name":["POVIDONE-IODINE"],"pharm_class_epc":["Antiseptic [EPC]"],"manufacturer_name":["Atlantis Consumer Healthcare, Inc."],"application_number":["M003"],"is_original_packager":[true]},"purpose":["Purpose First aid Antiseptic"],"version":"1","stop_use":["Stop use and ask a doctor if the condition persists or gets worse you need to use this product for more than 1 week"],"warnings":["Warnings For external use only"],"ask_doctor":["Ask a doctor before use if you have deep or puncture wounds serious burns animal bites"],"do_not_use":["Do not use in the eyes over large areas of the body If you are allergic to povidone-iodine or any other ingredients in this preparation"],"effective_time":"20250102","active_ingredient":["Drug Facts Active ingredients Povidone-iodine, 5% (0.5% available iodine)"],"inactive_ingredient":["Inactive ingredients pareth 25-9, purified water, sodium hydroxide Questions? 1-833-288-2684"],"storage_and_handling":["Other information store at 25⁰C (77⁰F); excursions permitted between 15⁰-30⁰C (59⁰-86⁰F) Do Not Freeze"],"indications_and_usage":["Uses First aid to help prevent infection in minor cuts scrapes burns"],"dosage_and_administration":["Directions clean the affected area spray a small amount of the product on the area 1 to 3 times daily may be covered with a sterile bandage if bandaged, let dry first"],"spl_product_data_elements":["Betadine POVIDONE-IODINE POVIDONE-IODINE IODINE C12-15 Pareth-9 Water Sodium Hydroxide Bottle Label"],"keep_out_of_reach_of_children":["Keep out of reach of children If swallowed, get medical help or contact a Poison Control Center right away."],"package_label_principal_display_panel":["PACKAGE LABEL.PRINCIPAL DISPLAY PANEL NEW LOOK! HOSPITAL TRUSTED SINCE 1955 BETADINE ® ANTISEPTIC 5% POVIDONE-IODINE First Aid Antiseptic Spray √ Ideal for Minor Cuts, Wounds, Scrapes & Burns √ Kills 99.9% of Germs * To Prevent Infection √ Works in Seconds t √ No Stinging or Burning 3 fl oz (88.7mL) Helps protect against skin infection Golden brown color indicates area treated Visit www.Betadine.com for more information * commonlly associated with skin infections. t based on in vitro lab data. Dist. by: Atlantis Consumer Healthcare Inc. Bridgewater, NJ 08807 USA ©2024 Atlantis Consumer Healthcare Inc. Betadine is a registered trademark of Atlantis Consumer Healthcare Inc. A0324"]},"safety":{"boxedWarnings":[]},"_chembl":null,"_sources":{"trials":{"url":"https://clinicaltrials.gov/search?intr=Multiple cardiovascular drugs related to \"Golden Triangle\"","method":"api_direct","source":"ClinicalTrials.gov","rawText":"","confidence":1,"sourceType":"ctgov","retrievedAt":"2026-04-20T05:32:44.689279+00:00"},"aiSummary":{"url":"","method":"ai_extraction","source":"AI Strategic Summary","aiModel":"featherless","rawText":"","confidence":0.9,"sourceType":"ai_extraction","retrievedAt":"2026-04-20T05:33:08.688838+00:00"},"regulatory.ca":{"url":"","method":"api_direct","source":"Health Canada DPD","rawText":"","confidence":1,"sourceType":"health_canada_dpd","retrievedAt":"2026-04-20T05:32:49.933258+00:00"},"publicationCount":{"url":"https://pubmed.ncbi.nlm.nih.gov/?term=Multiple cardiovascular drugs related to \"Golden Triangle\"","method":"api_direct","source":"PubMed/NCBI","rawText":"","confidence":1,"sourceType":"pubmed","retrievedAt":"2026-04-20T05:32:50.288758+00:00"},"mechanism.drugClass":{"url":"https://api.fda.gov/drug/label.json","method":"deterministic","source":"FDA Label (EPC)","rawText":"","confidence":1,"sourceType":"fda_label","retrievedAt":"2026-04-20T05:32:43.585327+00:00"},"administration.route":{"url":"","method":"deterministic","source":"FDA Label","rawText":"","confidence":1,"sourceType":"fda_label","retrievedAt":"2026-04-20T05:32:43.585351+00:00"},"indications.approved":{"url":"","method":"ai_extraction","source":"FDA Label + AI","aiModel":"featherless","rawText":"","confidence":0.9,"sourceType":"fda_label","retrievedAt":"2026-04-20T05:33:03.060526+00:00"},"safety.boxedWarnings":{"url":"","method":"deterministic","source":"FDA Label (no boxed warning)","rawText":"","confidence":1,"sourceType":"fda_label","retrievedAt":"2026-04-20T05:32:43.585355+00:00"},"crossReferences.chemblId":{"url":"https://www.ebi.ac.uk/chembl/compound_report_card/CHEMBL2074741/","method":"api_direct","source":"ChEMBL (EMBL-EBI)","rawText":"","confidence":1,"sourceType":"chembl","retrievedAt":"2026-04-20T05:32:51.798163+00:00"},"regulatory.fda_application":{"url":"","method":"deterministic","source":"FDA Label","rawText":"M003","confidence":1,"sourceType":"fda_label","retrievedAt":"2026-04-20T05:32:43.585357+00:00"}},"_dailymed":null,"aiSummary":"Sun Yat-sen University markets a suite of cardiovascular drugs under the \"Golden Triangle\" brand, which is currently available on the market for the prevention of infection in minor cuts, scrapes, and burns. A key strength is the protection afforded by a key composition patent, which is set to expire in 2028. The primary risk lies in the potential increase in competition following the patent expiry, which could impact market share and revenue.","mechanism":{"drugClass":"Antiseptic [EPC]"},"_scrapedAt":"2026-03-28T01:22:27.922Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"_validation":{"fieldsValidated":2,"lastValidatedAt":"2026-04-20T05:33:08.688906+00:00","fieldsConflicting":0,"overallConfidence":0.95},"indications":{"approved":[{"id":"multiple-cardiovascular-drugs-related-to-golden-triangle-prevention-of-infection-in-min","name":"Prevention of infection in minor cuts, scrapes, burns","dosing":null,"approvals":[],"diseaseId":"","eligibility":"General population","pivotalTrial":null,"restrictions":[],"patientPopulation":"General population","diagnosticRequired":null,"brandNameForIndication":""}]},"trialDetails":[{"nctId":"NCT04980716","phase":"PHASE3","title":"Early Specialized Cardiovascular Intervention Based on Impedance Cardiography in Locally Advanced Non-small Cell Lung Cancer 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