{"id":"mucinex-se","safety":{"commonSideEffects":[{"rate":null,"effect":"Nausea"},{"rate":null,"effect":"Vomiting"},{"rate":null,"effect":"Dizziness"},{"rate":null,"effect":"Headache"},{"rate":null,"effect":"Rash"}]},"_chembl":{"chemblId":"CHEMBL1201054","moleculeType":"Small molecule","molecularWeight":"192.07"},"_dailymed":{"setId":"2eeafd83-230c-af92-e063-6294a90a984e","title":"MUCINEX SINUS MAX SINUS PRESSURE SEVERE CONGESTION (OXYMETAZOLINE HCI) SPRAY [RB HEALTH (US) LLC]"},"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Guaifenesin is an expectorant that works by thinning mucus in the airways, making it easier to cough up and clear from the respiratory tract. This reduces the sensation of chest congestion and facilitates mucus drainage. Mucinex SE is an extended-release formulation designed to provide prolonged action over 12 hours.","oneSentence":"Guaifenesin reduces mucus viscosity and promotes clearance of respiratory secretions to relieve chest congestion.","_ai_confidence":"high"},"_scrapedAt":"2026-03-27T23:56:00.558Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Productive cough due to bronchitis, common cold, or other respiratory conditions"}]},"trialDetails":[{"nctId":"NCT03644095","phase":"PHASE1","title":"Bioequivalence Study Comparing Mucinex Extended-release 600 mg Tablets to Immediate-release Guaifenesin 600 mg in Healthy Volunteers","status":"COMPLETED","sponsor":"Reckitt Benckiser Inc.","startDate":"2009-01-16","conditions":"Healthy Subjects","enrollment":30}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["guaifenesin bi-layer tablet","Guaifenesin bi-layer tablet"],"phase":"marketed","status":"active","brandName":"Mucinex® SE","genericName":"Mucinex® SE","companyName":"Reckitt Benckiser Inc.","companyId":"reckitt-benckiser-inc","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Guaifenesin reduces mucus viscosity and promotes clearance of respiratory secretions by increasing hydration of mucus. Used for Productive cough due to common cold, bronchitis, or other respiratory conditions.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":1,"withResults":1},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}