{"id":"morphine-and-glucagon","safety":{"commonSideEffects":[{"rate":null,"effect":"Nausea and vomiting"},{"rate":null,"effect":"Constipation"},{"rate":null,"effect":"Dizziness"},{"rate":null,"effect":"Respiratory depression"},{"rate":null,"effect":"Hyperglycemia (from glucagon)"}]},"_chembl":{"chemblId":"CHEMBL5665374","moleculeType":null,"molecularWeight":"285.34"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Morphine acts as a mu-opioid receptor agonist to provide analgesia and pain relief. Glucagon is a peptide hormone that increases blood glucose by stimulating hepatic glycogenolysis and gluconeogenesis. This combination may be used in clinical settings where pain management is needed alongside prevention or treatment of hypoglycemia, though such fixed combinations are uncommon in standard practice.","oneSentence":"Morphine provides opioid analgesia while glucagon raises blood glucose, a combination potentially used to manage pain while preventing opioid-induced hypoglycemia or to address concurrent pain and hypoglycemic episodes.","_ai_confidence":"low"},"_scrapedAt":"2026-03-27T23:55:51.008Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Pain management with concurrent hypoglycemia risk or treatment (investigational/institutional use)"}]},"trialDetails":[{"nctId":"NCT05389813","phase":"PHASE2, PHASE3","title":"Comparison Between Oxycodone and Pregabalin as Preemptive Analgesia","status":"UNKNOWN","sponsor":"An-Najah National University","startDate":"2021-08-15","conditions":"Anesthesia","enrollment":150},{"nctId":"NCT00155376","phase":"PHASE4","title":"Intravenous-Morphine and Glucagon-Usage Enhanced MR Cholangiography","status":"UNKNOWN","sponsor":"National Taiwan University Hospital","startDate":"2005-09","conditions":"Liver Disease","enrollment":100}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"morphine and glucagon","genericName":"morphine and glucagon","companyName":"National Taiwan University Hospital","companyId":"national-taiwan-university-hospital","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Morphine provides opioid analgesia while glucagon raises blood glucose, a combination potentially used to manage pain while preventing opioid-induced hypoglycemia or to address concurrent pain and hypoglycemic episodes. Used for Pain management with concurrent hypoglycemia risk or treatment (investigational/institutional use).","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}