{"id":"morclofone","rwe":[{"pmid":"41210757","year":"2025","title":"Targeting Ubiquitin-Specific Protease 7 (USP7): A Pharmacophore-Guided Drug Repurposing and Physics-Based Molecular Simulation Study.","finding":"","journal":"ACS omega","studyType":"Clinical Study"},{"pmid":"3058135","year":"1988","title":"Clinical trials with the new antitussive levodropropizine in adult bronchitic patients.","finding":"","journal":"Arzneimittel-Forschung","studyType":"Clinical Study"}],"tags":[{"label":"morclofone","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"R05DB25","category":"atc"},{"label":"Active","category":"status"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"nitux","offLabel":[],"synonyms":["morclofone","dimeclophenone","dimecolphenone","nitux"],"timeline":[],"approvals":[],"brandName":"Nitux","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"morclofone","explanation":"Unfortunately, the exact mechanism of action of Nitux is not well understood, and more research is needed to determine how it works. In general, small molecule drugs like Nitux are designed to bind to specific proteins or receptors in the body, which can help to regulate various cellular processes. This binding can either activate or inhibit the target, leading to changes in the body's normal functioning.","oneSentence":"Nitux works by interacting with a specific target in the body to produce its therapeutic effect.","technicalDetail":"Nitux is a small molecule that binds to a specific target, likely a protein or receptor, to produce its therapeutic effect. The exact nature of this interaction is unknown, but it is thought to involve a reversible binding process that alters the target's activity. Further research is needed to determine the precise details of this interaction."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/1841","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=MORCLOFONE","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T12:50:19.226328","biosimilars":[],"competitors":[{"drugName":"benzonatate","drugSlug":"benzonatate","fdaApproval":"1958-02-10","genericCount":13,"patentStatus":"Off-patent — generic available","relationship":"same-class"},{"drugName":"pentoxyverine","drugSlug":"pentoxyverine","fdaApproval":"","relationship":"same-class"},{"drugName":"clofedanol","drugSlug":"clofedanol","fdaApproval":"","relationship":"same-class"}],"genericName":"morclofone","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[{"drugId":"benzonatate","brandName":"benzonatate","genericName":"benzonatate","approvalYear":"1958","relationship":"same-class"},{"drugId":"pentoxyverine","brandName":"pentoxyverine","genericName":"pentoxyverine","approvalYear":"","relationship":"same-class"},{"drugId":"clofedanol","brandName":"clofedanol","genericName":"clofedanol","approvalYear":"","relationship":"same-class"}],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"UNII":"VY62TIB872","CHEBI":"CHEBI:135657","INN_ID":"3277","UMLSCUI":"C0066796","ChEMBL_ID":"CHEMBL2105158","KEGG_DRUG":"D07395","DRUGBANK_ID":"DB13558","PUBCHEM_CID":"35949","MESH_SUPPLEMENTAL_RECORD_UI":"C037579"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":2,"therapeuticAreas":["Other"],"atcClassification":{"source":"DrugCentral","atcCode":"R05DB25","allCodes":["R05DB25"]},"biosimilarFilings":[],"recentPublications":[{"date":"2025 Nov 4","pmid":"41210757","title":"Targeting Ubiquitin-Specific Protease 7 (USP7): A Pharmacophore-Guided Drug Repurposing and Physics-Based Molecular Simulation Study.","journal":"ACS omega"},{"date":"1988 Aug","pmid":"3058135","title":"Clinical trials with the new antitussive levodropropizine in adult bronchitic patients.","journal":"Arzneimittel-Forschung"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Nitux is a small molecule modality. It is also known by the synonyms MORCLOFONA, MORCLOFONE, and PLAUSITIN.","enrichmentLevel":3,"visitCount":3,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}