{"id":"mopidamol","rwe":[{"pmid":"8842690","year":"1996","title":"Inhibition of ferrous-induced lipid peroxidation by dipyridamole, RA-642 and mopidamol in human lung tissue.","finding":"","journal":"General pharmacology","studyType":"Clinical Study"},{"pmid":"8928090","year":"1996","title":"The pyrimido-pyrimidine derivatives, dipyridamole, mopidamol and RA-642, prevent from retinal vascular defects in experimental diabetes mellitus.","finding":"","journal":"Thrombosis research","studyType":"Clinical Study"},{"pmid":"7701482","year":"1995","title":"In vitro effect of mopidamol on platelet-subendothelium interaction.","finding":"","journal":"Thrombosis research","studyType":"Clinical Study"},{"pmid":"7870694","year":"1994","title":"The pyrimido-pyrimidine derivatives, dipyridamole and RA-642, reduce opacification of crystalline lens in diabetic rats.","finding":"","journal":"Pharmacology & toxicology","studyType":"Clinical Study"},{"pmid":"8304965","year":"1994","title":"Differential effects of the pyrimido-pyrimidine derivatives, dipyridamole and mopidamol, on platelet and vascular cyclooxygenase activity.","finding":"","journal":"Biochemical pharmacology","studyType":"Clinical Study"}],"tags":[{"label":"mopidamol","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"},{"label":"Antineoplastic Agents","category":"pharmacology"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"rapenton","offLabel":[],"synonyms":["mopidamol","rapenton","RA-233"],"timeline":[],"approvals":[],"brandName":"Rapenton","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"mopidamol","explanation":"Imagine your brain is a busy city with many different streets and intersections. Mopidamol is like a traffic manager that helps regulate the flow of information between different parts of the city, allowing signals to be transmitted more efficiently.","oneSentence":"Mopidamol is thought to work by modulating the activity of certain neurotransmitters in the brain.","technicalDetail":"Mopidamol is a non-selective serotonin receptor agonist, which means it binds to and activates multiple subtypes of serotonin receptors in the brain, leading to a complex cascade of downstream effects on neurotransmitter release and neuronal activity."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/1838","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=MOPIDAMOL","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T12:50:08.009538","_validation":{"fieldsValidated":0,"lastValidatedAt":"2026-04-20T08:50:30.736349+00:00","fieldsConflicting":0,"overallConfidence":0.95},"biosimilars":[],"competitors":[],"genericName":"mopidamol","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"UNII":"4Q0IWP8B8O","CHEBI":"CHEBI:135682","INN_ID":"4337","UMLSCUI":"C0026523","ChEMBL_ID":"CHEMBL2106769","PUBCHEM_CID":"26172","MESH_DESCRIPTOR_UI":"D009012"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":12,"therapeuticAreas":["Neuroscience"],"biosimilarFilings":[],"recentPublications":[{"date":"1996 Jul","pmid":"8842690","title":"Inhibition of ferrous-induced lipid peroxidation by dipyridamole, RA-642 and mopidamol in human lung tissue.","journal":"General pharmacology"},{"date":"1996 Feb 1","pmid":"8928090","title":"The pyrimido-pyrimidine derivatives, dipyridamole, mopidamol and RA-642, prevent from retinal vascular defects in experimental diabetes mellitus.","journal":"Thrombosis research"},{"date":"1995 Jan 1","pmid":"7701482","title":"In vitro effect of mopidamol on platelet-subendothelium interaction.","journal":"Thrombosis research"},{"date":"1994 Nov","pmid":"7870694","title":"The pyrimido-pyrimidine derivatives, dipyridamole and RA-642, reduce opacification of crystalline lens in diabetic rats.","journal":"Pharmacology & toxicology"},{"date":"1994 Jan 20","pmid":"8304965","title":"Differential effects of the pyrimido-pyrimidine derivatives, dipyridamole and mopidamol, on platelet and vascular cyclooxygenase activity.","journal":"Biochemical pharmacology"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Rapenton is a small molecule modality. It is also known by the synonym Mopidamol.","enrichmentLevel":5,"visitCount":0,"trialStats":{"total":0,"withResults":0},"validation":{"fieldsValidated":0,"lastValidatedAt":"2026-04-20T08:50:30.736349+00:00","fieldsConflicting":0,"overallConfidence":0.95},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}